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    3-FEA molecular structure

    3-FEA Stats & Data

    NPS DataHub
    MW217.71
    FormulaC11H17ClFN
    IUPACN-Ethyl-1-(3-fluorophenyl)propan-2-amine
    SMILES[Cl-].CCNC(C)Cc1cccc(F)c1.[H+]
    InChIKeyVWEIOFROPKRPJC-UHFFFAOYSA-N
    Phenethylamines; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Amphetamine
    Psychoactive Class Stimulant
    Half-Life Estimated 5–8 hours (no human PK data)

    Receptor Profile

    Receptor Actions

    Inhibitors
    Serotonin-dopamine-norepinephrine reuptake inhibitor (SNDRI)
    Other
    Serotonin-dopamine-norepinephrine releasing agent (SNDRA)

    History & Culture

    3-Fluoroethamphetamine belongs to a series of designer fluorinated amphetamine derivatives that emerged in the 2010s, which includes related compounds such as 2-FA, 2-FMA, 3-FA, 4-FMA, and 4-FA. These substances were developed as novel psychoactive compounds for the research chemical market. The compound first appeared on the grey market in mid-2016, when it became available for purchase through online research chemical vendors. Unlike many other stimulants, 3-FEA has not been documented being sold on the streets and its distribution has remained primarily within online research chemical communities. Due to its recent emergence, 3-FEA has an extremely limited history of human use, and virtually no scientific research has been conducted on its effects in humans.

    Effect Profile

    Curated + 5 Reports
    Empathogen 5.1

    Strong sensory enhancement with moderate stimulation and euphoria, low empathy

    Empathy / Social Openness×3
    3
    Euphoria / Mood Elevation×2
    6
    Stimulation×1
    7
    Sensory Enhancement×1
    8
    Stimulant 4.4

    Strong anxiety/jitters with moderate euphoria, mild stimulation, low focus

    Stimulation / Energy×3
    5
    Euphoria / Mood Lift×2
    7
    Focus / Productivity×2
    3
    Anxiety / Jitters×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki
    Half-Life
    Estimated 5–8 hours (no human PK data)
    Addiction Potential
    Moderate; redosing urges may appear after the peak. Limited preclinical data indicate withdrawal-like behaviors after repeated administration; most user reports describe a softer crash than amphetamine or 4-FA, but binges increase adverse effects.

    Cross-Tolerances

    amphetamines
    60% ●○○
    other fluoroamphetamines (e.g., 3-FA, 4-FA)
    60% ●○○
    serotonergic releasers (e.g., MDMA)
    40% ●○○

    Experience Report Analysis

    Erowid
    5 Reports
    2016–2019 Date Range
    5 With Age Data
    2 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 5 experience reports (5 Erowid)

    5 Reports
    2 Effects Detected
    2 Positive
    0 Adverse
    0 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 2

    Stimulation 100.0% 70%
    Euphoria 60.0% 70%

    Adverse Effects 0

    Real-World Dose Distribution

    62K Doses

    From 14 individual dose entries

    Insufflated (n=12)

    Median: 20.0mg 25th: 15.12mg 75th: 26.25mg 90th: 39.0mg
    mg/kg median: 0.233 mg/kg 75th: 0.385

    Legal Status

    Country Status Notes
    Austria Illegal (NPSG) Production and sale prohibited under the Neue-Psychoaktive-Substanzen-Gesetz (New Psychoactive Substances Act). This legislation covers novel psychoactive substances not explicitly listed in traditional drug schedules.
    Canada Schedule I (analog) Controlled as an amphetamine analog under the Controlled Drugs and Substances Act. Schedule I substances carry the most severe penalties for trafficking and possession.
    France Not scheduled As of December 2024, not explicitly listed as a controlled substance. Possession exists in a legal grey area, though this status may change.
    Germany Controlled (NpSG) Regulated under the Neue-psychoaktive-Stoffe-Gesetz since November 26, 2016. Production, import with intent to distribute, administration to others, and commercial trading are criminal offenses. Possession is prohibited but does not carry criminal penalties.
    New Zealand Schedule 3 Controlled as an amphetamine analog under national drug legislation. Schedule 3 substances are considered to have moderate potential for harm.
    Switzerland Controlled (Verzeichnis E) Regulated as a derivative of α-methylphenethylamine under Verzeichnis E point 130 of the narcotics scheduling ordinance. An exemption exists for scientific or industrial applications.
    United Kingdom Class A Controlled under the amphetamine analog clause of the Misuse of Drugs Act 1971. Class A classification carries the most severe penalties, including up to 7 years for possession and life imprisonment for supply.
    United States Unscheduled (Analogue Act applies) Not explicitly scheduled federally but may be prosecuted under the Federal Analogue Act (21 U.S.C. § 813) as substantially similar to amphetamine. This applies only when the substance is intended for human consumption, potentially subjecting it to Schedule II restrictions.

    Harm Reduction

    drugs.wiki

    Sold solely as a research chemical with variable and sometimes misrepresented content; drug checking is strongly advised. Advanced laboratory methods (e.g., GC/MS or LC–HRMS) are required to reliably distinguish 3-FEA from related isomers like 3-FA or 4-FA; reagent kits cannot confirm identity and mislabeling has been documented in the stimulant market. Oral administration is generally preferred over insufflation for fluoroamphetamines due to significant nasal irritation and mucosal injury risk. Combining with other stimulants or high caffeine markedly increases cardiovascular strain; stick to one stimulant at a time and avoid energy drinks. As an entactogenic stimulant, 3-FEA carries typical risks of hyperthermia and dehydration; sip fluids regularly but avoid overhydration to reduce hyponatremia risk, and take cooling breaks in hot environments. Redosing beyond the initial peak increases adverse effects (nausea, tremor, jaw tension, insomnia) while providing diminishing returns; allow full offset and adequate sleep before considering any reuse. Do not self-treat stimulant comedowns with beta-blockers; if you experience chest pain, severe headache, confusion, or very high blood pressure/heart rate, seek urgent care—benzodiazepines are the first-line treatment in emergency settings for stimulant toxicity. Evidence on human pharmacokinetics is limited; metabolism pathways are not established, so be especially cautious if taking CYP2D6-inhibiting medications (inference from MDMA data).

    References

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