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    3-FPM molecular structure

    3-FPM Stats & Data

    3f-p 3-fph Pal-593 3f-phenmetrazine 3fpm 3fp
    NPS DataHub
    MW231.7
    FormulaC11H15ClFNO
    CAS1803562-83-5
    IUPAChydrogen 2-(3-fluorophenyl)-3-methylmorpholine chloride
    SMILES[Cl-].CC1NCCOC1c1cccc(F)c1.[H+]
    InChIKeyMHJBXKFJWSBWRE-UHFFFAOYSA-N
    Phenethylamines; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Amphetamine
    Psychoactive Class Stimulant
    Half-Life Unknown; user reports suggest shorter than phenmetrazine (16–31 h for phenmetrazine), but residual stimulation can persist into the next day after high/repeated dosing.

    Interaction Warnings

    stimulants

    3-FPM can be potentially dangerous in combination with other stimulants as it can increase one's heart rate and blood pressure to dangerous levels.

    mdma

    The neurotoxic effects of MDMA may be increased when combined with amphetamines.

    cocaine

    This combination may increase strain on the heart.

    Receptor Profile

    Receptor Actions

    Inhibitors
    Dopamine reuptake inhibitor
    Norepinephrine reuptake inhibitor
    Other
    Dopamine-norepinephrine releasing agent (DNRA)

    Effect Profile

    Curated + 24 Reports
    Stimulant 8.8

    Strong stimulation, euphoria, focus, and anxiety/jitters

    Stimulation / Energy×3
    1010
    Euphoria / Mood Lift×2
    1010
    Focus / Productivity×2
    1010
    Anxiety / Jitters×1
    1010
    Catalog Erowid

    Tolerance & Pharmacokinetics

    drugs.wiki
    Half-Life
    Unknown; user reports suggest shorter than phenmetrazine (16–31 h for phenmetrazine), but residual stimulation can persist into the next day after high/repeated dosing.
    Addiction Potential
    Moderate to high relative to its subtle primary effects; many users describe strong 'more-ish' cravings and binge risk, especially with nasal or vaped ROAs.

    Tolerance Decay

    Full tolerance 1d Half tolerance 3d Baseline ~7d

    Tolerance to desirable effects builds rapidly within a day of repeated dosing and partially resets over 3–7 days; anecdotal reports suggest cross-tolerance with other stimulants. Data quality is low and based on community self-reports rather than controlled studies.

    Cross-Tolerances

    Amphetamines
    50% ●○○
    Methylphenidate
    30% ●○○
    Cathinones
    40% ●○○

    Experience Report Analysis

    Erowid
    24 Reports
    2014–2020 Date Range
    23 With Age Data
    18 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 24 experience reports (24 Erowid)

    24 Reports
    18 Effects Detected
    6 Positive
    9 Adverse
    3 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 6

    Stimulation 75.0% 70%
    Euphoria 66.7% 70%
    Focus Enhancement 54.2% 70%
    Empathy 33.3% 70%
    Music Enhancement 33.3% 70%
    Tactile Enhancement 20.8% 70%

    Adverse Effects 9

    Anxiety 45.8% 70%
    Increased Heart Rate 29.2% 70%
    Jaw Clenching 25.0% 70%
    Sweating 20.8% 70%
    Pupil Dilation 20.8% 70%
    Memory Suppression 12.5% 70%
    Headache 12.5% 70%
    Appetite Suppression 12.5% 70%
    Muscle Tension 12.5% 70%

    Real-World Dose Distribution

    62K Doses

    From 57 individual dose entries

    Oral (n=23)

    Median: 48.0mg 25th: 29.5mg 75th: 67.5mg 90th: 121.2mg
    mg/kg median: 0.678 mg/kg 75th: 0.867

    Insufflated (n=32)

    Median: 32.5mg 25th: 20.0mg 75th: 42.5mg 90th: 68.0mg
    mg/kg median: 0.328 mg/kg 75th: 0.564

    Form / Preparation

    Most common forms and preparations reported

    Body-Weight Dosing

    Dose relative to body weight from reports with weight data

    Oral

    Median: 0.638 mg/kg IQR: 0.403–1.181 mg/kg n=8

    Insufflated

    Median: 0.424 mg/kg IQR: 0.284–0.862 mg/kg n=7

    Redose Patterns

    Redosing behavior across 21 reports

    71.4% Redosed
    2.6 Avg Doses
    90m Median Interval

    Legal Status

    Country Status Notes
    France As of december 2024, 3-FPM is not explicitly scheduled. It is thus legal to possess, although in a grey area.
    Germany 3-FPM is controlled under the NpSG ( New Psychoactive Substances Act ) as of November 26, 2016. As of 2022 due to changes in the NpSG it's legal again if sold only for research purposes.
    Israel 3-FPM is illegal to buy, sell or possess in Israel as of 2017.
    Sweden The public health agency suggested the classification of the drug as an illegal narcotic on June 1, 2015.
    Switzerland 3-Fluorophenmetrazine is illegal
    United Kingdom 3-FPM is illegal to produce, supply, or import under the Psychoactive Substance Act, which came into effect on May 26th, 2016.
    United States 3-FPM may be considered to be an analogue of phenmetrazine, a Schedule II drug , under the Federal Analogue Act if it is intended for human consumption. It is an illegal Schedule I controlled substance in the state of Virginia, as well as its isomers such as 4-FPM.
    United States - Virginia it is also a schedule I substance

    Harm Reduction

    drugs.wiki

    3-FPM is a phenmetrazine analogue; like phenmetrazine it appears to act primarily on dopamine and norepinephrine systems with minimal direct serotonin releasing activity reported, which lowers—but does not eliminate—serotonin syndrome concerns when used alone. However, cardiovascular and neurobehavioral risks typical of stimulants still apply, especially with redosing. Erowid and community reports emphasize strong 'more-ish' qualities and that vaped or insufflated routes are particularly compulsive; pre-planning maximum total dose and avoiding short-interval redoses can reduce harms. Nasal administration is notably caustic and can acutely damage mucosa; if used, finely crush, keep lines small, alternate nostrils, rinse with sterile saline before/after, and allow multi‑day healing intervals to prevent erosions or septal injury. Batch-to-batch variability and adulteration have been reported; where available, use a certified drug checking service and be skeptical of off‑white/pink or gritty material, unexpected residues on heating, or weak effects at typical doses. Combining with alcohol or other stimulants meaningfully increases heart rate, blood pressure, and vasoconstriction; this can raise risks of chest pain, palpitations, and overheating—avoid such mixes and monitor exertion and ambient temperature. Hydration and nutrition matter: sip water regularly (about 250 ml per hour at rest, up to 500 ml per hour if active) and include electrolytes after several hours; eat a balanced meal before use to mitigate appetite suppression and comedown fatigue. Sleep debt strongly worsens anxiety and low mood on the comedown; plan sufficient sleep opportunity, and avoid consecutive‑day use to limit tolerance and compulsion. Pharmacokinetic data for 3‑FPM are sparse; phenmetrazine (the parent drug) has a long half‑life (16–31 h), but 3‑FPM subjectively feels shorter; residual stimulation into the next day can still occur after high or repeated dosing. Given variable market quality, be alert for unexpected effects (e.g., unusual sedation or very long duration) that may indicate mislabeling or cuts; discontinue and consider checking the sample if this occurs. People with hypertension, arrhythmias, cardiovascular disease, or significant anxiety disorders should avoid use or seek medical guidance; stimulants increase cardiac workload and can exacerbate anxiety and bruxism.

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