3-FPM Stats & Data
[Cl-].CC1NCCOC1c1cccc(F)c1.[H+]MHJBXKFJWSBWRE-UHFFFAOYSA-NInteraction Warnings
3-FPM can be potentially dangerous in combination with other stimulants as it can increase one's heart rate and blood pressure to dangerous levels.
The neurotoxic effects of MDMA may be increased when combined with amphetamines.
This combination may increase strain on the heart.
Receptor Profile
Receptor Actions
Effect Profile
Curated + 24 ReportsStrong stimulation, euphoria, focus, and anxiety/jitters
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Tolerance to desirable effects builds rapidly within a day of repeated dosing and partially resets over 3–7 days; anecdotal reports suggest cross-tolerance with other stimulants. Data quality is low and based on community self-reports rather than controlled studies.
Cross-Tolerances
Experience Report Analysis
ErowidDemographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 24 experience reports (24 Erowid)
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 6
Adverse Effects 9
Real-World Dose Distribution
62K DosesFrom 57 individual dose entries
Oral (n=23)
Insufflated (n=32)
Form / Preparation
Most common forms and preparations reported
Body-Weight Dosing
Dose relative to body weight from reports with weight data
Oral
Insufflated
Redose Patterns
Redosing behavior across 21 reports
Legal Status
| Country | Status | Notes |
|---|---|---|
| France | As of december 2024, 3-FPM is not explicitly scheduled. | It is thus legal to possess, although in a grey area. |
| Germany | 3-FPM is controlled under the NpSG ( New Psychoactive Substances Act ) as of November 26, 2016. | As of 2022 due to changes in the NpSG it's legal again if sold only for research purposes. |
| Israel | 3-FPM is illegal to buy, sell or possess in Israel as of 2017. | |
| Sweden | The public health agency suggested the classification of the drug as an illegal narcotic on June 1, 2015. | |
| Switzerland | 3-Fluorophenmetrazine is illegal | |
| United Kingdom | 3-FPM is illegal to produce, supply, or import under the Psychoactive Substance Act, which came into effect on May 26th, 2016. | |
| United States | 3-FPM may be considered to be an analogue of phenmetrazine, a Schedule II drug , under the Federal Analogue Act if it is intended for human consumption. | It is an illegal Schedule I controlled substance in the state of Virginia, as well as its isomers such as 4-FPM. |
| United States - Virginia | it is also a schedule I substance |
Harm Reduction
drugs.wiki3-FPM is a phenmetrazine analogue; like phenmetrazine it appears to act primarily on dopamine and norepinephrine systems with minimal direct serotonin releasing activity reported, which lowers—but does not eliminate—serotonin syndrome concerns when used alone. However, cardiovascular and neurobehavioral risks typical of stimulants still apply, especially with redosing. Erowid and community reports emphasize strong 'more-ish' qualities and that vaped or insufflated routes are particularly compulsive; pre-planning maximum total dose and avoiding short-interval redoses can reduce harms. Nasal administration is notably caustic and can acutely damage mucosa; if used, finely crush, keep lines small, alternate nostrils, rinse with sterile saline before/after, and allow multi‑day healing intervals to prevent erosions or septal injury. Batch-to-batch variability and adulteration have been reported; where available, use a certified drug checking service and be skeptical of off‑white/pink or gritty material, unexpected residues on heating, or weak effects at typical doses. Combining with alcohol or other stimulants meaningfully increases heart rate, blood pressure, and vasoconstriction; this can raise risks of chest pain, palpitations, and overheating—avoid such mixes and monitor exertion and ambient temperature. Hydration and nutrition matter: sip water regularly (about 250 ml per hour at rest, up to 500 ml per hour if active) and include electrolytes after several hours; eat a balanced meal before use to mitigate appetite suppression and comedown fatigue. Sleep debt strongly worsens anxiety and low mood on the comedown; plan sufficient sleep opportunity, and avoid consecutive‑day use to limit tolerance and compulsion. Pharmacokinetic data for 3‑FPM are sparse; phenmetrazine (the parent drug) has a long half‑life (16–31 h), but 3‑FPM subjectively feels shorter; residual stimulation into the next day can still occur after high or repeated dosing. Given variable market quality, be alert for unexpected effects (e.g., unusual sedation or very long duration) that may indicate mislabeling or cuts; discontinue and consider checking the sample if this occurs. People with hypertension, arrhythmias, cardiovascular disease, or significant anxiety disorders should avoid use or seek medical guidance; stimulants increase cardiac workload and can exacerbate anxiety and bruxism.
References
Data Sources
Cited References
- Backberg et al. 2016 - Adverse events related to 3-FPM (STRIDA project)
- Blough et al. 2011 - Phenylmorpholines patent
- Erowid: 3F-Phenmetrazine Vault
- Erowid Novel Drug Briefs: 3-FPM
- Gibbons et al. 2016 - Emerging NPS in the United Kingdom
- Mayer et al. 2017 - Acute kidney injury and limb ischaemia with 3-FPM
- Pifl et al. 2017 - Fluorinated phenmetrazine as monoamine transporter substrates
- Soh & Elliott 2014 - Phenmetrazine pharmacology review
- Welter et al. 2017 - 3-FPM metabolism and biotransformation
- TripSit Factsheet: 3-FPM
- Erowid: 3-FPM Vault
- Wikipedia: 3 Fluorophenmetrazine
Drugs.wiki References
- PubChem: 3-Fluorophenmetrazine compound page (CID 54673723)
- DrugBank: Phenmetrazine monograph (parent drug pharmacology/half-life)
- Erowid newsletter #29 blurb on 3‑FPM (history/character)
- Erowid: Novel Drug Briefs 2 (3‑FPM dosage and 'more-ishness')
- Bluelight: 3‑FPM Discussion Thread V2 (ROA-specific practices; fiendish redosing; nasal/vaped cautions)
- Drug Users Bible: 3‑FPM page (reference dose ranges and overview)
- SubstanceSearch: 3‑FPM (duration ranges collated from user reports)
- Hi‑Ground harm-reduction: snorting safer‑use tips (applicable to caustic stimulants)
- DrugWise: Amphetamine page (stimulant HR and cardiovascular cautions)