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    3-MMC molecular structure

    3-MMC Stats & Data

    3m Meow Mcat 3-meph Metaphedrone 3mmc 3-methylmethcathinone 3methylmethcathinone
    NPS DataHub
    MW213.71
    FormulaC11H16ClNO
    CAS1246816-62-5
    IUPAC2-(Methylamino)-1-(3-methylphenyl)propan-1-one
    SMILES[Cl-].CNC(C)C(=O)c1cccc(C)c1.[H+]
    Phenethylamines; Cathinones; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Cathinone
    Psychoactive Class Stimulant / Entactogen

    Interaction Warnings

    mdma

    The neurotoxic effects of MDMA may be increased when combined with other stimulants.

    cocaine

    This combination may increase strain on the heart.

    Receptor Profile

    Receptor Actions

    Inhibitors
    Serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI)
    Other
    Serotonin-norepinephrine-dopamine releasing agent (SNDRA)

    History & Culture

    2012–present

    3-MMC was first encountered in Sweden in 2012, emerging on the online research chemical market shortly after the banning of mephedrone in numerous countries. It was created as a designer drug specifically chosen to mimic and replace the functional and structural features of its recently-controlled predecessor. The compound was sold as a research chemical, typically in powdered form, and quickly became a prominent example of contemporary designer drug development in response to prohibition. There is no known or reported medical use of 3-MMC; since its emergence it has been used primarily for recreational purposes.

    2016–2023

    In 2016, the United Nations Office on Drugs and Crime conducted a critical review of 3-MMC but ultimately decided not to recommend international control. However, following a subsequent period of increased abuse beginning around 2019, this decision was revisited. The earlier assessment was overturned and 3-MMC was placed into Schedule II of the United Nations Convention on Psychotropic Substances 1971 in March 2023, prompting many member nations to implement or strengthen domestic controls.

    2023–present

    Despite its prohibition as a recreational substance, 3-MMC has attracted interest as a potential pharmaceutical compound. The biotechnology company Clearmind Medicine has been developing 3-MMC for the potential treatment of dyskinesias, with the compound in preclinical research as of August 2023. American biotech company MindMed has filed patents to use 3-MMC for conditions including social anxiety disorder, post-traumatic stress disorder, and as an adjunct in couples therapy. Additionally, the Dutch company Period Pill has been conducting clinical trials investigating 3-MMC for the treatment of menstrual symptoms, with a successful trial completed at the University of Maastricht. The company has sought patent coverage in multiple jurisdictions. The first in-human clinical safety study of 3-MMC was published in December 2024, marking a significant milestone in the compound's transition from unregulated research chemical to potential therapeutic agent.

    Effect Profile

    Curated + 26 Reports
    Empathogen 9.6

    Strong empathy, euphoria, and sensory enhancement with moderate stimulation

    Empathy / Social Openness×3
    107.5
    Euphoria / Mood Elevation×2
    1010
    Stimulation×1
    79.6
    Sensory Enhancement×1
    104.4
    Catalog BlueLight
    Stimulant 5.1

    Strong euphoria and anxiety/jitters with mild stimulation, low focus

    Stimulation / Energy×3
    5
    Euphoria / Mood Lift×2
    10
    Focus / Productivity×2
    3
    Anxiety / Jitters×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 4d Baseline ~5d

    Experience Report Analysis

    Erowid BlueLight
    17 Reports
    2012–2023 Date Range
    15 With Age Data
    14 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid + Bluelight

    Effects aggregated from 26 experience reports (17 Erowid + 9 Bluelight)

    26 Reports
    48 Effects Detected
    16 Positive
    20 Adverse
    12 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 16

    Euphoria 73.1% 84%
    Stimulation 57.7% 85%
    Empathy 50.0% 83%
    Sociability Enhancement 44.4% 81%
    Body High 44.4% 85%
    Contentment 33.3% 92%
    Thought Acceleration 33.3% 75%
    Focus Enhancement 30.8% 78%
    Tactile Enhancement 29.4% 70%
    Music Enhancement 26.9% 85%
    Tingling 22.2% 88%
    Joy 22.2% 85%
    Libido Enhancement 22.2% 85%
    Introspection 17.6% 70%
    Orgasm Enhancement 11.1% 80%
    Enhanced Colors 11.1% 75%

    Adverse Effects 20

    Insomnia 33.3% 85%
    Confusion 29.4% 70%
    Jaw Clenching 26.9% 78%
    Muscle Tension 23.5% 70%
    Anxiety 23.1% 85%
    Irritability 22.2% 82%
    Emotional Blunting 11.1% 65%
    Nausea 11.1% 70%
    Dry Mouth 11.1% 75%
    Metallic Taste 11.1% 80%
    Headache 11.1% 70%
    Diarrhea 11.1% 75%
    Body Load 11.1% 80%
    Distractibility 11.1% 80%
    Muscle Spasm 11.1% 90%
    Dizziness 11.1% 85%
    Hot Flashes 11.1% 90%
    Cold Flashes 11.1% 85%
    Restlessness 11.1% 85%
    Sadness 11.1% 80%

    Real-World Dose Distribution

    62K Doses

    From 28 individual dose entries

    Oral (n=15)

    Median: 100.0mg 25th: 72.5mg 75th: 155.0mg 90th: 176.0mg
    mg/kg median: 1.653 mg/kg 75th: 2.112

    Form / Preparation

    Most common forms and preparations reported

    Redose Patterns

    Redosing behavior across 13 reports

    53.8% Redosed
    1.9 Avg Doses
    60m Median Interval

    Legal Status

    UN Convention on Psychotropic Substances 1971 (Schedule II, placed March 2023)
    Country Status Notes
    Austria Illegal (NPSG) Prohibited under the Neue-Psychoaktive-Substanzen-Gesetz (New Psychoactive Substances Act). Possession, production, and sale are illegal.
    Brazil Illegal Listed on Portaria SVS/MS nº 344. Possession, production, and sale are prohibited under this regulation.
    China Controlled Banned since October 2015 along with numerous other synthetic compounds. This ban significantly impacted global availability as Chinese chemical companies were primary manufacturers.
    Czech Republic Illegal Banned substance under national drug control legislation.
    Germany Anlage I BtMG Controlled under Anlage I of the Betäubungsmittelgesetz (Narcotics Act, Schedule I) since December 13, 2014. Manufacturing, possession, import, export, purchase, sale, procurement, and dispensing without license are prohibited.
    India Narcotic Designated as a narcotic substance on February 8, 2024, making possession, production, and distribution illegal.
    Netherlands List I (Opiumwet) Initially classified as a List II (soft drug) substance effective October 28, 2021. Subsequently reclassified to List I (hard drug) in April 2024, carrying more severe penalties for possession and distribution.
    Poland II-P Category Drug Classified as a II-P category controlled substance since April 25, 2024, making possession, production, and distribution illegal.
    Sweden Narcotic Classified as a narcotic substance under Swedish drug control legislation.
    Switzerland Controlled (Verzeichnis E) Regulated as a defined derivative of cathinone under Verzeichnis E point 1. Use is permitted for legitimate scientific or industrial purposes only.
    Turkey Illegal Classified as a controlled drug. Possession, production, supply, and importation are prohibited.
    United Kingdom Class B Controlled as a Class B substance under the Misuse of Drugs Act 1971 through the cathinone catch-all clause, which covers structurally related compounds.
    United States Schedule I Illegal as a positional isomer of the controlled substance mephedrone. Explicitly designated as a controlled substance on December 13, 2023, and categorized by the DEA as a Schedule I positional isomer.
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