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    3C-P molecular structure

    3C-P Stats & Data

    3c-proscaline 3cp
    NPS DataHub
    MW253.34
    FormulaC14H23NO3
    CAS501700-11-4
    IUPAC1-(3,5-Dimethoxy-4-propoxyphenyl)propan-2-amine
    SMILESCCCOc1c(OC)cc(CC(C)N)cc1OC
    InChIKeyKKMCHCCXGKYEKJ-UHFFFAOYSA-N
    Phenethylamines; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Amphetamine
    Psychoactive Class Psychedelic / Stimulant
    Half-Life Unknown in humans; duration suggests long-acting effects beyond 10 hours.

    Receptor Profile

    Receptor Actions

    Agonists
    5-HT2A receptor agonist (partial)
    5-HT2C receptor agonist (partial)

    Effect Profile

    Curated + 7 Reports
    Psychedelic 8.0

    Strong visuals, auditory effects, body load, and headspace

    Visual Intensity×3
    10
    Headspace Depth×3
    8
    Auditory Effects×1
    10
    Body Load / Somatic Effects×1
    10
    Stimulant 5.1

    Strong anxiety/jitters and euphoria with mild stimulation and focus

    Stimulation / Energy×3
    5
    Euphoria / Mood Lift×2
    9
    Focus / Productivity×2
    4
    Anxiety / Jitters×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki
    Half-Life
    Unknown in humans; duration suggests long-acting effects beyond 10 hours.
    Addiction Potential
    Low; little evidence of compulsive use. Main risks are prolonged stimulation, vasoconstriction, insomnia, and cardiovascular strain at higher doses.

    Tolerance Decay

    Full tolerance 1d Half tolerance 3d Baseline ~7d

    As with other 5‑HT2A psychedelics, acute tolerance develops rapidly after a single session and tends to decay across one to two weeks. Data for 3C‑P specifically are anecdotal; estimates extrapolated from mescaline/2C/DOx literature.

    Cross-Tolerances

    Other serotonergic psychedelics (PEA and tryptamine classes)
    50% ●○○
    DOx series (e.g., DOC, DOI)
    60% ●○○

    Experience Report Analysis

    Erowid
    7 Reports
    2003–2022 Date Range
    3 With Age Data
    15 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 7 experience reports (7 Erowid)

    7 Reports
    15 Effects Detected
    8 Positive
    4 Adverse
    3 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 8

    Color Enhancement 85.7% 70%
    Stimulation 85.7% 70%
    Euphoria 71.4% 70%
    Empathy 57.1% 70%
    Music Enhancement 57.1% 70%
    Tactile Enhancement 57.1% 70%
    Focus Enhancement 42.9% 70%
    Body High 42.9% 70%

    Adverse Effects 4

    Nausea 57.1% 70%
    Anxiety 42.9% 70%
    Increased Heart Rate 42.9% 70%
    Pupil Dilation 42.9% 70%

    Real-World Dose Distribution

    62K Doses

    From 11 individual dose entries

    Oral (n=9)

    Median: 33.0mg 25th: 25.0mg 75th: 40.0mg 90th: 40.6mg
    mg/kg median: 0.487 mg/kg 75th: 0.598

    Form / Preparation

    Most common forms and preparations reported

    Legal Status

    Country Status Notes
    Japan 3C-P is a controlled substance in Japan effective February 28th, 2018.
    United Kingdom It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.
    United States 3C-P is technically not scheduled in the United States, but could be considered an analog of mescaline and may, therefore, be considered a Schedule I drug under the Federal Analogue Act.

    Harm Reduction

    drugs.wiki

    3C‑P is very rare and poorly characterized; assume high uncertainty. Start low, go slow, and strongly consider a 1–2 mg oral allergy test before any full dose. Come‑up is often slow (≥90 minutes), which can tempt premature redosing; wait at least 3 hours before any consideration of additional dosing. Expect sustained stimulation and possible vasoconstriction (cold or tingly extremities); avoid additional vasoconstrictors and take gentle movement breaks to promote circulation. Oral administration is preferred over insufflation to reduce nasal harm and erratic absorption. Because of long duration and residual alertness, avoid late‑day dosing and plan for sleep disruption; do not counteract with large amounts of alcohol or multiple sedatives. People with cardiovascular disease, hypertension, or arrhythmia should avoid use; monitor pulse and temperature in physically demanding settings. Use lab drug checking where available or at minimum multi‑reagent testing; the gray market has a history of mislabeling phenethylamines. Ensure accurate weighing (calibrated mg scale) and consider volumetric dilution for precise titration. Avoid driving or safety‑critical tasks for at least 16–24 hours after dosing.

    References

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