Substance taken at the time: 4-CEC, negligible amount of alcohol (1/3 of a small champagne glass) Other substances: 900mg of depakote daily for the past year (Bipolar disorder) I was on an empty stomach, last meal was about 5 hours before dosing. Background: The day started out as usual.
4-CEC
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: 4-chloroethcathinone, 4-chloro-n-ethylcathinone
Summary
4-CEC is a poorly researched synthetic cathinone with limited human use data. Preclinical studies suggest neurotoxic properties including tissue damage to liver, kidney, and brain. The substance acts as a serotonin releasing agent, raising concerns about potential serotonergic toxicity.
Dose Information
Dose basis. Ranges are compiled from scattered user reports and general cathinone HR guides; there are no formal human pharmacology data specific to 4‑CEC. Always weigh with a 0.001 g scale and start low—consider an allergy test of 1–5 mg. Large interindividual variability has been reported across cathinones. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-50mg | 50-100mg | 100-200mg | 200mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 15-30 min | 30-60 min | 2-3 hrs | 2-3 hrs | 4.75-7.5 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
6.1
Strong
6/10
Strong euphoria and anxiety/jitters with moderate focus, mild stimulation
Stimulation / Energy
×3
5
stimulation
wakefulness
Euphoria / Mood Lift
×2
10
physical euphoria
cognitive euphoria
euphoria
motivation enhancement
Focus / Productivity
×2
7
focus enhancement
motivation enhancement
thought acceleration
Anxiety / Jitters
×1
10
anxiety
increased heart rate
teeth grinding
vasoconstriction
Based on reports from:
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 4-CEC there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
⬇ Download import file
Import this file as custom substances
and you get "4-CEC (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Name
4-CEC
Unit
mg
Description
4-CEC Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 10 · light 10-50 · common 50-100 · strong 100-200 · heavy 200+ Oral duration: onset 15-30m · come-up 0.5-1h · peak 2-3h · offset 2-3h · total 4.75-7.5h · after-effects 2-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 75 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Tolerance Decay
Half tolerance
2d
Baseline
~5d
No formal data. As with other stimulants, acute tachyphylaxis and diminished effect with redosing within a session are commonly reported for cathinones; spacing use by weeks reduces risk of compulsive patterns.
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Increased heart rate
- Teeth grinding
- Nausea
- Insomnia
- Pupil dilation
- Vasoconstriction
- Sedation
- Decreased appetite
Positive
- Cognitive euphoria
- Motivation enhancement
- Focus enhancement
- Wakefulness
- Euphoria
Negative
- Anxiety
- Confusion
- Compulsive redosing
- Thought acceleration
- Time distortion
Positive
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Increased libido
Negative
- Appetite suppression
- Light sensitivity
- Dehydration
- Disinhibition
- Drifting
- Dulled perception
Combinations
Cross-Check 4-CEC with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 1 report 1 neutral visit
4-CEC's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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