Aceburic acid
Aliases: G, Ghb, Xyrem, Alcover, Sodium oxybate
Categories
Summary
Aceburic acid is rapidly hydrolyzed by plasma esterases to gamma-hydroxybutyrate (GHB) within approximately 5-10 minutes, functioning as a GHB prodrug with slightly slower onset than GBL but faster than 1,4-butanediol. Due to molecular weight differences (146 vs 104), approximately 1.4 times more mass is needed compared to GHB for equivalent effects. Oral solutions are strongly acidic (pH approximately 3) and may cause throat irritation; buffering with food-grade carbonate reduces discomfort. The narrow therapeutic window between desired effects and overdose makes precise measurement with a 0.01 g scale essential. Redosing sooner than 2 hours greatly increases overdose risk.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral / Sublingual | 0.5-1.5g | 1-2.5g | 2-4g | 5-10g+ |
| Oral | 0.5-1g | 1-2.5g | 2.5-4g | 4g+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral / Sublingual | 15-30 min | 10-20 min | 30-90 min | 1-2 hrs | 1-3 hrs | 90-0 min |
| Rectal | 10-20 min | 5-15 min | 30-90 min | 1-2 hrs | 1-3 hrs | 90-0 min |
| Insufflated (Irritating) | 5-15 min | 5-10 min | 30-90 min | 1-2 hrs | 1-3 hrs | 90-0 min |
| Oral | 6-30 min | 12-18 min | 48-90 min | 12-30 min | 2-4 hrs | 90-0 min |
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7โ14 days for partial reset; full reset may take weeks โ tolerance loss greatly increases overdose risk
Effects
Positive
- Muscle Relaxation
- Muscle relaxation
- Physical euphoria
- Pain relief
- Anxiolytic
Negative
- Motor impairment
- Nausea
- Respiratory depression
- Sedation
- Dystaxia
Positive
- Cognitive Euphoria
- Anxiety Suppression
- Empathy Enhancement
- Affection Enhancement
- Sociability Enhancement
- Dream Potentiation
Negative
- Motor Control Loss
- Dizziness
- Memory Suppression
- Compulsive Redosing
Positive
- Increased Libido
- Increased libido
- Increased music appreciation
- Appetite enhancement
Negative
- Disinhibition
- Spatial Disorientation
- Double vision
- Dehydration
- Dulled perception
- Optical sliding