Adinazolam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 17 combo interactions documented
- classified Tentative
- 3 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 17 combo interactions documented
- classified Tentative
Aliases: Deracyn, U-41,123, Adinazolamum
Summary
Adinazolam is a short-acting triazolobenzodiazepine originally investigated as both an anxiolytic and antidepressant but never FDA approved. In clinical trials (10-90 mg/day) it showed rapid relief of anxiety and modest antidepressant efficacy comparable to tricyclics with fewer anticholinergic effects. Human studies found adinazolam causes the most mental and physical sedation compared to diazepam and lorazepam, along with significant mental unpleasantness.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-15mg | 15-30mg | 30-50mg | 50mg+ |
| Sublingual | 5-15mg | 15-30mg | 30-50mg | 50mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 10-25 min | 1-2 hrs | 1.5-3 hrs | 2-5 hrs |
| Sublingual | 10-25 min | 1-2 hrs | 1.5-3 hrs | 2-5 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong cognitive impairment and anxiolysis with moderate euphoria, mild sedation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Adinazolam there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Adinazolam Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 5-15 · common 15-30 · strong 30-50 · heavy 50+ Sublingual dose (mg): threshold <3 · light 5-15 · common 15-30 · strong 30-50 · heavy 50+ Oral duration: onset 10-25m · peak 1-2h · offset 1.5-3h · total 2-5h · after-effects 4-16h Sublingual duration: onset 10-25m · peak 1-2h · offset 1.5-3h · total 2-5h · after-effects 4-16h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 22.5 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Benzodiazepine tolerance develops to most effects with repeated use over days–weeks; cross-tolerance exists across the class and with Z-drugs. On discontinuation, tolerance decays slowly over weeks; clinical practice favors long, individualized tapers to minimize withdrawal. Data are derived largely from class-wide evidence and user reports rather than adinazolam-specific trials.
Cross-Tolerances
Effects
- Muscle Relaxation
- Physical Euphoria
- Anxiolytic
- Respiratory Depression
- Motor impairment
- Sedation
- Sedative
- Anxiety Suppression
- Cognitive Impairment
- Motor Control Loss
- Memory Suppression
- Thought Deceleration
- Amnesia
- Dizziness
- Increased libido
- Appetite enhancement
- Disinhibition
- Acuity suppression
- Double vision
- Decreased Libido
- Visual acuity suppression
- Dulled perception
- Perception of bodily heaviness
Combinations
Cross-Check Adinazolam with another substanceHelpful Links
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