ALD-52 Stats & Data
1a-lsd
1a-lad
1-acetyl-lsd
Orange sunshine
ald52
1alsd
NPS DataHub
MW365.48
FormulaC22H27N3O2
CAS3270-02-8
IUPAC(6~{a}~{R},9~{R})-4-acetyl-~{N},~{N}-diethyl-7-methyl-6,6~{a},8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide
SMILES
CCN(CC)C(=O)C1CN(C)C2Cc3cn(C(C)=O)c4cccc(C2=C1)c34InChIKey
FJOWXGYLIWJFCH-OXQOHEQNSA-N
Chemical Class
Lysergamide
Psychoactive Class
Psychedelic
Receptor Profile
Receptor Actions
Agonists
5-HT2A receptor partial agonist
5-HT2C receptor partial agonist
5-HT1A receptor partial agonist
D2 receptor agonist (through LSD metabolite)
Effect Profile
Curated + 36 Reports
Psychedelic
8.8
Strong visuals, headspace, auditory effects, and body load
Visual Intensity×3
10108.0
Headspace Depth×3
10104.0
Auditory Effects×1
10104.0
Body Load / Somatic Effects×1
109.64.0
Catalog
Erowid
BlueLight
Based on reports from:
Community Effects
TripSit
Negative
dehydration
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Full tolerance
1h
Half tolerance
10d
Baseline
~14d
Cross-Tolerances
LSD
90%
●○○
Psilocybin
80%
●○○
Psilocin
80%
●○○
Mescaline
60%
●○○
DMT
80%
●○○
5-MeO-DMT
80%
●○○
2C-B
60%
●○○
2C-E
60%
●○○
31
Reports
2013–2019
Date Range
29
With Age Data
28
Effects Detected
Demographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
Erowid + BluelightEffects aggregated from 36 experience reports (31 Erowid + 5 Bluelight)
36
Reports
52
Effects Detected
18
Positive
21
Adverse
13
Neutral
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 18
Color Enhancement
61.3%
70%
Music Enhancement
61.3%
70%
Euphoria
54.8%
70%
Focus Enhancement
47.2%
85%
Stimulation
44.5%
80%
Empathy
41.9%
70%
Body High
38.7%
70%
Tactile Enhancement
38.7%
70%
Joy
20.0%
85%
Silliness
20.0%
80%
Contentment
20.0%
80%
Well-Being
20.0%
85%
Analysis Enhancement
20.0%
75%
Sociability Enhancement
20.0%
80%
Gratitude
20.0%
75%
Awe
20.0%
75%
Introspection
19.4%
70%
Creativity Enhancement
9.7%
70%
Adverse Effects 21
Anxiety
77.8%
92%
Confusion
52.8%
80%
Muscle Spasm
40.0%
88%
Motor Suppression
40.0%
75%
Nausea
33.3%
95%
Thought Loops
25.0%
90%
Body Load
20.0%
85%
Social Anxiety
20.0%
85%
Paranoid Ideation
20.0%
75%
Delusion
20.0%
85%
Panic
20.0%
90%
Fear
20.0%
90%
Vomiting
20.0%
95%
Melting/flowing
20.0%
80%
Anger
20.0%
75%
Visual Fragmentation
20.0%
70%
Muscle Tension
13.9%
85%
Pupil Dilation
12.9%
70%
Headache
12.9%
70%
Sweating
9.7%
70%
Dose-Response Correlation
How effect frequency changes across dose levels
View data table
| Effect | Common (n=10) |
|---|---|
| Visual Distortions | 100.0% |
| Anxiety | 80.0% |
| Confusion | 70.0% |
| Euphoria | 60.0% |
| Focus Enhancement | 60.0% |
| Tactile Enhancement | 60.0% |
| Color Enhancement | 40.0% |
| Body High | 40.0% |
| Music Enhancement | 40.0% |
| Sedation | 30.0% |
| Auditory Effects | 30.0% |
| Time Distortion | 30.0% |
| Empathy | 30.0% |
| Introspection | 30.0% |
| Pupil Dilation | 20.0% |
Dose–Effect Mapping
Experience ReportsHow reported effects shift across dose tiers, based on 31 experience reports.
Limited tier coverage — most reports fall within the Common range. Effects at other dose levels may not be represented.
Oral dose range:
100.0–250.0 µg
(median 125.0 µg)
| Effect | Common (n=10) | |
|---|---|---|
| visual distortions | ||
| anxiety | ||
| confusion | ||
| euphoria | ||
| focus enhancement | ||
| tactile enhancement | ||
| color enhancement | ||
| body high | ||
| music enhancement | ||
| sedation | ||
| auditory effects | ||
| time distortion | ||
| empathy | ||
| introspection | ||
| pupil dilation | ||
| nausea | ||
| appetite suppression | ||
| thought loops | ||
| jaw clenching | ||
| increased heart rate |
Showing top 20 of 21 effects
Dosage Distribution
Dose distribution from experience reports
Median: 125.0 µg
IQR: 100.0–250.0 µg
n=12
Real-World Dose Distribution
62K DosesFrom 36 individual dose entries
Oral (n=18)
Median: 0.15mg
25th: 0.11mg
75th: 0.24mg
90th: 0.27mg
mg/kg median: 0.002
mg/kg 75th: 0.003
Sublingual (n=12)
Median: 0.17mg
25th: 0.12mg
75th: 0.27mg
90th: 0.3mg
mg/kg median: 0.003
mg/kg 75th: 0.004
Common Combinations
Most co-occurring substances in experience reports
Form / Preparation
Most common forms and preparations reported
Body-Weight Dosing
Dose relative to body weight from reports with weight data
Oral
Median: 0.002 mg/kg
IQR: 0.002–0.003 mg/kg
n=12
Sublingual
Median: 0.004 mg/kg
IQR: 0.001–0.008 mg/kg
n=7
Redose Patterns
Redosing behavior across 27 reports
11.1%
Redosed
1.1
Avg Doses
Legal Status
| Country | Status | Notes |
|---|---|---|
| Austria | ALD-52 is technically not illegal but it may fall in the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich) as an analogue of LSD. | |
| Denmark | ALD-52 is not listed as an illegal substance in Denmark as of April 2019, and its chemical class 'lysergamide' is not banned under the Analogue Act (some LSD analogues are, however, prohibited). | |
| Finland | ALD-52 is labeled a controlled psychoactive substance in Finland as of 2014. | |
| Germany | ALD-52 is controlled under the NpSG as of July 18, 2019. | Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized. |
| Latvia | ALD-52 is illegal in Latvia. | Although it is not officially scheduled, it is controlled as an LSD structural analog due to an amendment made on June 1, 2015. |
| Poland | ALD-52 is a NPS class drug in Poland, making it illegal to possess or distribute. | |
| Romania | ALD-52 is illegal to produce or sell in Romania. | It is not included directly in the list of controlled substances, but it is included in an analogue act. However, it is not, as of yet, classified as illegal to use. |
| Singapore | ALD-52 is a class A controlled drug, and is illegal to traffic, manufacture, import, export, possess, or consume in Singapore as of December 1, 2019, punishable with a minimum of five years' imprisonment and five strokes of the cane. | |
| Switzerland | Since March 2018, ALD-52 is illegal in Switzerland and has been put in the RS 812.121.11. | |
| United Kingdom | On June 10, 2014, the UK Advisory Council on the Misuse of Drugs (ACMD) recommended that ALD-52 be specifically named in the UK Misuse of Drugs Act as a class A drug despite not identifying it as ever having been sold or any harm associated with its use. | The UK Home office accepted this advice and announced a ban of the substance to be enacted on 6 January 2015 as part of The Misuse of Drugs Act 1971 (Amendment) (No. 2) Order 2014. |
| United States | ALD-52 is unscheduled in the United States. | It may be considered an analogue of LSD, a Schedule I drug under the Controlled Substances Act. As such, the sale for human consumption or the use for illicit non-medical or scientific use could be prosecuted as crimes under the Federal Analogue Act however could be legal for medical and research uses like a research chemical. |
References
Cited References
- Erowid: ALD-52 Vault
- Isomer Design TiHKAL Entry 26 (LSD)
- Nichols (2016) Psychedelics - Pharmacological Reviews
- Passie et al. (2008) The Pharmacology of Lysergic Acid Diethylamide
- The Big & Dandy ALD-52 Thread (Bluelight)
- TripSit: Drug Combination Chart
- Troxler & Hofmann (1957) Substitutionen am Ringsystem der Lysergsäure
- Wagmann et al. (2019) In vitro metabolic fate of nine LSD-based new psychoactive substances