Home
    Disclaimer
    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    โš  Synthetic cannabinoids are far more potent and unpredictable than natural cannabis. They lack a ceiling effect and have been linked to seizures, psychosis, and death.

    CBL Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 2 corroborating sources
    • descriptive-only dose data
    • 16 combo interactions documented
    • toxicity data (PsychonautWiki)
    • classified Research-chemical

    Aliases: Cbp, Cannabipinol, Pentylcannabicyclol

    Summary dose.wiki

    CBL is a photodegradation product of cannabichromene (CBC), occurring naturally in aged or UV-exposed Cannabis. Human pharmacology remains almost completely unstudied; however, recent 2025 research revealed CBL has high affinity for the 5-HT1A serotonin receptor, acting as a potent positive allosteric modulator at low concentrations. A 1976 study in rabbits showed convulsions and death at 8 mg/kg, though this limited two-animal study offers minimal guidance for human safety.

    Dose Information dose.wiki

    ROA Light Common Strong Heavy
    Oral Nodata - - -
    Sublingual Nodata - - -
    Inhaled Nodata - - -
    Light Common Strong Heavy

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track CBL there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    Name
    CBL
    Unit
    mg
    Description
    CBL
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose: threshold Unknown ยท light Nodata
    Sublingual dose: threshold Unknown ยท light Nodata
    Inhaled dose: threshold Unknown ยท light Nodata
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over weeks of regular use via CB1 receptor downregulation
    Reset 2โ€“4 weeks for most users; heavy users may need longer

    Tolerance Decay

    Half tolerance 14d Baseline ~21d

    No data describing tolerance to CBL; assume none or minimal until characterized. Do not extrapolate tolerance patterns from THC or CBD.

    Effects

    Combinations

    Cross-Check CBL with another substance

    Helpful Links