CBL
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- descriptive-only dose data
- 16 combo interactions documented
- PubChem toxicity data
- classified Research-chemical
- 2 corroborating sources
- descriptive-only dose data
- 16 combo interactions documented
- PubChem toxicity data
- classified Research-chemical
Aliases: Cbp, Cannabipinol, Pentylcannabicyclol
Summary
CBL is a photodegradation product of cannabichromene (CBC), occurring naturally in aged or UV-exposed Cannabis. Human pharmacology remains almost completely unstudied; however, recent 2025 research revealed CBL has high affinity for the 5-HT1A serotonin receptor, acting as a potent positive allosteric modulator at low concentrations. A 1976 study in rabbits showed convulsions and death at 8 mg/kg, though this limited two-animal study offers minimal guidance for human safety.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | Nodata | - | - | - |
| Sublingual | Nodata | - | - | - |
| Inhaled | Nodata | - | - | - |
Tolerance
Tolerance Decay
No data describing tolerance to CBL; assume none or minimal until characterized. Do not extrapolate tolerance patterns from THC or CBD.
Effects
Combinations
Cross-Check CBL with another substanceHelpful Links
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