Clobromazolam Stats & Data
Brc1ccc2c(c1)C(=NCc1nnc(C)n12)c1ccccc1ClBUTCFAZTKZDYCN-UHFFFAOYSA-NEffect Profile
CuratedStrong anxiolysis, sedation, and cognitive impairment with moderate euphoria
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Benzodiazepine sedative/hypnotic tolerance can develop rapidly with daily use; partial reversal requires weeks to months of abstinence and is highly individualized. Data are largely anecdotal; treat any numerical model as a rough guide only. Avoid consecutive‑day use to limit tolerance and dependence risk.
Cross-Tolerances
Harm Reduction
drugs.wikiPhenazolam is the same compound as clobromazolam; it first appeared on the market circa 2016 and has no approved medical use. Forum meta-reports consistently place its potency in the sub‑milligram range, with ~0.25 mg often compared to a typical anxiolytic dose range of diazepam; avoid any pressed tablets claiming multi‑milligram doses. Onset is notably slow for a triazolobenzodiazepine (often 1–2 h, sometimes 3 h), which greatly increases redosing risk and blackout potential. Volumetric dosing is essential: dissolve a known amount in a measured volume (e.g., 1 mg in 10–20 mL ethanol/propylene glycol), mix thoroughly, and measure doses with an oral syringe; do not eyeball powders or shave tablets. Wait a full 3–4 hours before considering any redose due to delayed peak and amnesia. Multiple reports describe next‑day impairment lasting well beyond the perceived high; avoid driving or hazardous tasks for at least 24 h after dosing. Novel benzodiazepines are widely found in counterfeit ‘Xanax/Valium’-type tablets and in non‑benzo samples; mislabeling and extreme dose variability have been repeatedly documented by drug‑checking and early warning systems — treat unknown tablets/solutions as suspect and test where possible. Combining with opioids, alcohol, GHB/GBL, dissociatives, or gabapentinoids is the main cause of life‑threatening events; treat these as hard contraindications. Naloxone reverses opioids but not benzodiazepines; always prioritize airway and breathing in mixed‑drug poisonings until help arrives. Flumazenil can precipitate acute withdrawal and seizures in dependent users and should only be given in a clinical setting by trained staff. Because supply may include bromazolam or other benzos mis‑sold as clobromazolam, assume mislabeling until proven otherwise and start at the absolute minimum dose.
References
Drugs.wiki References
- Isomer Design — Clobromazolam/Phenazolam entry (synonyms, structure)
- Bluelight — Clobromazolam / Phenazolam Megathread (dosing, onset/duration, blackout risk)
- Reddit — PSA: Beware of Clobromazolam (pressed 2 mg bars; blackout reports)
- TripSit — Drug combinations (benzos + tramadol marked dangerous)
- TripSit — Volumetric Converter (resource for accurate micro‑dosing solutions)
- EUDA/EMCDDA — New benzodiazepines in Europe: public health risks and fake medicines
- Saferparty Zürich — Warning: Bromazolam sold as Etizolam (mislabeling in benzo tablets)
- Toronto Drug Checking — Benzodiazepines frequently found in fentanyl supply and other samples (context for unexpected benzos)
- DrugBank — Triazolam (class exemplar; CYP3A4 substrate)
- DrugWise — Benzodiazepines overview (dependence & illicit variants)
- DrugWise — Xylazine (risks; appearance in illicit opioid markets)
- TripSit — Diazepam factsheet (memory loss, motor impairment; blackout risk at higher doses)