Clomethiazole
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- partial dose data
- duration data present
- classified Tentative
- classified Research-chemical
- 1 source
- partial dose data
- duration data present
- classified Tentative
- classified Research-chemical
Summary
Structurally related to Thiamine (vitamin B1), but with binding potential at the GABAa site, which causes it to produce effects most like those of a barbiturate: an effective sedative and hypnotic. Originally developed by Hoffman-LaRoche in the 1930s, it has seen use as a treatment for acute alcohol withdrawal.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 100-150mg | 150-200mg | - | 200mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 15-40 min | 5-8 hrs | 5-8 hrs |
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Clomethiazole Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 100 · light 100-150 · common 150-200 · heavy 200+ Oral duration: onset 15-40m · peak 5-8h · total 5-8h · after-effects 1-16h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 175 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Effects
- Anxiolytic
- Muscle Relaxant
- Dystaxia
- Hypnotic
- Sedation
- Reduced anxiety
- Amnesia
- Confusion
- Disinhibition
- Dulled perception
Combinations
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