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    Cocaethylene Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source

    Aliases: Homocaine, Ethylcocaine

    Summary TheDrug.Wiki

    Cocaethylene is not found in nature and forms exclusively in the liver through transesterification when cocaine and alcohol are consumed together. It carries 18-25 times greater risk of immediate death compared to cocaine alone. Cocaethylene is more cardiotoxic and hepatotoxic than either parent substance, with increased risk of seizures, liver damage, compromised immune function, and sudden cardiac death.

    Dose Information TheDrug.Wiki

    Light Common Strong Heavy

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 4.6
    Moderate+ 5/10

    Strong euphoria and anxiety/jitters with mild stimulation

    Stimulation / Energy ×3
    5
    increased energy stimulation
    Euphoria / Mood Lift ×2
    10
    physical euphoria cognitive euphoria enhanced euphoria increased confidence
    Focus / Productivity ×2
    0
    Anxiety / Jitters ×1
    8
    anxiety paranoia increased heart rate

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Effects TheDrug.Wiki

    Positive
    • Increased energy
    • Stimulation
    • Physical euphoria
    • Pain relief
    Negative
    • Cardiovascular stimulation
    • Increased heart rate
    • Nausea
    • Pupil dilation
    • Abnormal heartbeat
    Neutral
    • Sedation
    Positive
    • Enhanced euphoria
    • Increased confidence
    • Increased sociability
    • Cognitive euphoria
    Negative
    • Anxiety
    • Paranoia
    • Dizziness
    Neutral
    • Reduced inhibition
    • Time distortion
    • Increased risk-taking behavior
    Positive
    • Increased libido
    • Auditory enhancement
    Negative
    • Light sensitivity
    • Appetite suppression
    Neutral
    • Drifting
    • Internal hallucination
    • Auditory hallucinations
    • Internal hallucinations
    • Perception of increased weight
    • Auditory distortion

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Bluelight 1 thread 1 neutral visit
    Cocaethylene Not Experienced Fun But Unexpectedly Strong neutral

    My drug background: I'm normally a stim-loving girl - meth and adderall - and I sometimes do coke, although overall I'm underwhelmed by it. I mean, it's nice, but just nice, not awesome. And It doesn't fuck me up seriously, just buzzes me a bit.

    scraped 2026-03-14

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