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    Datura Stats & Data

    Toloache Malpitte Stinkweed Loco seed Moonflower
    Psychoactive Class Depressant / Psychedelic

    Receptor Profile

    Receptor Actions

    Antagonists
    Competitive antagonist at muscarinic acetylcholine receptors M1 and M2 (anticholinergic)

    History & Culture

    The genus name originates from the Hindi "dhatūra" and Sanskrit "dhattūra," both terms for thorn-apple, with the Sanskrit specifically referencing Datura metel of Asia. The Ayurvedic text Sushruta Samhita records additional Sanskrit names for the genus, including "kanaka" and "unmatta." Mexican Spanish uses "toloache," a name traceable to the Nahuatl "tolohuaxihuitl"—literally "the plant with the nodding head." The American common name "jimsonweed" emerged from "Jamestown-Weed," documenting the plant's prevalence around the Virginia colony where it was recorded by colonist Robert Beverley.

    Archaeological and ethnographic evidence indicates Datura has served shamanic and religious functions across multiple continents since prehistoric times, with documented traditional use spanning the Americas, Europe, and the Indian subcontinent. Within Hindu practice, Datura holds sacred significance as an offering to Shiva and features in Ganesh Chaturthi celebrations honoring Ganesha. Indian traditions have long recognized the plant as both medicinal and toxic, with Datura metel incorporated into Ayurvedic practice since antiquity. Indigenous peoples throughout North and Central America developed sophisticated knowledge of the plant's properties. Anthropological research documents spiritual use among the Navajo and particularly the Havasupai peoples, while the Southern Paiute attributed divinatory properties to Datura, believing it could reveal the location of missing objects. Inhabitants of ancient California reportedly consumed the plant to induce visionary communion with deities. The Aztecs incorporated Datura into religious ceremonies and the practices of their medicine men, with some accounts describing its use in ritual sacrifice. Documented traditional use extends to Afghanistan, where the Malang employed Datura in shamanic initiation rites and practices for contacting spiritual realms. Ethnobotanist Wade Davis has also identified Datura as an ingredient in Haitian Vodou preparations associated with zombie phenomena.

    European folklore classifies Datura stramonium among the "witches' weeds"—a group including deadly nightshade, henbane, and mandrake—all characterized by their capacity to induce delirium and their longstanding association with death and sorcery. Medieval and early modern European traditions attributed particular significance to Datura as a component of "flying ointments," preparations purportedly used by witches to induce sensations of flight. Recipe manuscripts for these magical ointments from the early modern period, particularly in New England and Western Europe, regularly specified Datura stramonium as an ingredient. The plant's folkloric associations with the supernatural proved so persistent that during colonial anti-witchcraft campaigns, cultivating Datura in one's garden was considered ill-omened due to its reputation for facilitating incantations.

    1950–1965

    Datura's toxic properties have been exploited for criminal purposes throughout recorded history, particularly in Europe and India where it served as an instrument of murder and suicide. The plant's capacity to induce stupor made it especially effective for incapacitating victims. The magnitude of intentional poisonings is reflected in Indian government records: between 1950 and 1965, the State Chemical Laboratories in Agra investigated approximately 2,800 deaths attributed to Datura consumption. Historical accounts also describe the Thugs, a group of alleged robbers and assassins said to be devotees of the goddess Kali, who reportedly employed Datura to poison or sedate victims before strangling them during ritual practices.

    Effect Profile

    Curated + 304 Reports
    Psychedelic 6.9

    Strong visuals, auditory effects, and body load with mild headspace

    Visual Intensity×3
    10105.2
    Headspace Depth×3
    53.71.0
    Auditory Effects×1
    108.23.0
    Body Load / Somatic Effects×1
    104.53.4
    Catalog Erowid BlueLight

    Experience Report Analysis

    Erowid BlueLight
    284 Reports
    1990–2023 Date Range
    57 With Age Data
    29 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid + Bluelight

    Effects aggregated from 304 experience reports (284 Erowid + 20 Bluelight)

    304 Reports
    89 Effects Detected
    14 Positive
    52 Adverse
    23 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 14

    Anxiety Suppression 40.5% 88%
    Sedation 26.3% 78%
    Stimulation 25.4% 72%
    Color Enhancement 25.0% 75%
    Tactile Enhancement 22.5% 70%
    Focus Enhancement 20.1% 70%
    Music Enhancement 16.2% 70%
    Euphoria 14.1% 70%
    Empathy 12.3% 70%
    Body High 6.6% 85%
    Introspection 6.3% 70%
    Sociability Enhancement 5.0% 85%
    Muscle Relaxation 5.0% 75%
    Creativity Enhancement 2.1% 70%

    Adverse Effects 52

    Entity Imagery 70.0% 90%
    Amnesia 45.0% 88%
    Thought Disorganization 45.0% 83%
    Depersonalization 45.0% 79%
    Body Load 40.0% 76%
    Fear 40.0% 90%
    Dry Mouth 40.0% 89%
    Confusion 36.5% 88%
    Ataxia 35.0% 87%
    Delusion 35.0% 90%
    Pareidolia 30.0% 86%
    Paranoia 25.0% 87%
    Panic 25.0% 84%
    Pupil Dilation 21.7% 87%
    Memory Suppression 21.1% 90%
    Blurred Vision 20.0% 85%
    Nausea 16.1% 88%
    Heaviness 15.0% 83%
    Stomach Cramps 15.0% 80%
    Tremor 15.0% 82%

    Subjective Effect Ontology

    Experience Reports

    Structured effect tags extracted from 304 Erowid & Bluelight experience reports using a controlled vocabulary of 220+ canonical effects across 15 domains.

    Cognitive

    confusion 111 36.5%

    Emotional

    anxiety suppression 123 40.5%

    2 unique effects extracted · Derived from Erowid & Bluelight reports

    Real-World Dose Distribution

    62K Doses

    From 335 individual dose entries

    Oral (n=9)

    Median: 3000.0mg 25th: 2500.0mg 75th: 3500.0mg 90th: 4400.0mg
    mg/kg median: 41.336 mg/kg 75th: 49.781

    Common Combinations

    Most co-occurring substances in experience reports

    Form / Preparation

    Most common forms and preparations reported

    Redose Patterns

    Redosing behavior across 234 reports

    17.5% Redosed
    1.3 Avg Doses
    60m Median Interval

    Legal Status

    Country Status Notes
    United States Unscheduled / Legal Datura plants and their tropane alkaloids (scopolamine, hyoscyamine, atropine) are not scheduled under the Controlled Substances Act. The plant can be legally cultivated, possessed, and sold, in contrast to scheduled hallucinogens such as LSD or psilocybin mushrooms which remain prohibited.
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