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    DOx Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • no dose data
    • 18 combo interactions documented
    • PubChem toxicity data

    Summary PsychonautWiki

    Substituted dimethoxyamphetamines (also known as DOx) refers to a class of psychedelic amphetamines originally synthesized and documented by Alexander Shulgin in his investigation of psychoactive phenethylamines in the 1970s. Shulgin later published his findings along with other mescaline-derived compounds in his semi-autobiographical book/organic synthesis reference PiHKAL ("Phenethylamines I Have Known and Loved").

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 6.5
    Strong 6/10

    Strong visuals with mild headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    color enhancement drifting tracers pattern recognition enhancement visual distortions brightened colour
    Headspace Depth ×3
    4
    introspection time distortion confusion
    Auditory Effects ×1
    4
    auditory distortion
    Body Load / Somatic Effects ×1
    4
    nausea increased heart rate

    Tolerance

    Build-up develops rapidly after a single use (serotonergic psychedelic)
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects

    Positive
    • Stimulation
    • Mental/physical stimulation
    Negative
    • Nausea
    • Pupil dilation
    • Increased heart rate
    • Insomnia
    • Restlessness
    Neutral
    • Dilated pupils
    • Decreased appetite
    • Sedation
    Positive
    • Introspection
    • Euphoria
    • Wakefulness
    • Empathy
    • Insight
    • Analysis enhancement
    Negative
    • Anxiety
    • Confusion
    Neutral
    • Time distortion
    • Ego softening
    Positive
    • Color enhancement
    • Tracers
    • Increased music appreciation
    • Tactile enhancement
    • Enhanced tactile sensation
    • Pattern recognition enhancement
    • Brightened colour
    Neutral
    • Visual distortions
    • Drifting
    • Auditory distortion

    Combinations TripSit

    Cross-Check DOx with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Bluelight 4 threads 4 neutral visit
    Dox Inexperienced This One Is Funny neutral

    this trip was i bealeve my 8th or nineth time to take blotter unknown dox compound - date summer 07 it all starts again over at my friends apartment, i went over there after work like always.

    scraped 2026-03-14
    Dox Inexperienced The On Off Switch neutral

    Now i say DOx because i am absolutely certain it was not LSD, and what i experienced has the most similarities too a DOx compound, possibly DOB. This would of been the second time on these specific tabs, so my second time on DOx.

    scraped 2026-03-14
    Dox First Time Clouded Clarity neutral

    Picked up: two, white, unperf. blotter, suspected DOx compound Age: 21 Weight: 150 I believe this is my first trip report so i'll make it a good one. I've been involved in a loving relationship with psychdelics, mainly mushrooms for about 4 years now, taking mushrooms especially about 50 times in the that period.

    scraped 2026-03-14
    Dox Or 25x Nbome 1 Tab Familiar What Is It Its So Good neutral

    I keep skimming around the net and it sucks that if I had any Marquis liquid left I would simply give it a test, but I am inclined to believe this couple blotters I picked up is DOB/DOI or 25B-NBOMe/25I-NBOMe. Certainly convinced.

    scraped 2026-03-14

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