Summary
Substituted dimethoxyamphetamines (also known as DOx) refers to a class of psychedelic amphetamines originally synthesized and documented by Alexander Shulgin in his investigation of psychoactive phenethylamines in the 1970s. Shulgin later published his findings along with other mescaline-derived compounds in his semi-autobiographical book/organic synthesis reference PiHKAL ("Phenethylamines I Have Known and Loved").
Tolerance
Build-up
develops rapidly after a single use (serotonergic psychedelic)
Reset
7–14 days for baseline
Effects
Positive
- Stimulation
- Mental/physical stimulation
Negative
- Nausea
- Pupil dilation
- Increased heart rate
- Insomnia
- Restlessness
- Dilated pupils
- Decreased appetite
- Sedation
Positive
- Introspection
- Euphoria
- Wakefulness
- Empathy
- Insight
- Analysis enhancement
Negative
- Anxiety
- Confusion
- Time distortion
- Ego softening
Positive
- Color enhancement
- Tracers
- Increased music appreciation
- Tactile enhancement
- Enhanced tactile sensation
- Pattern recognition enhancement
- Brightened colour
Negative
- Visual distortions
- Drifting
- Auditory distortion