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    Ethylone molecular structure

    Ethylone Stats & Data

    Mdec Bk-mdea 3,4-mdec
    NPS DataHub
    MW221.26
    FormulaC12H15NO3
    CAS1112937-64-0
    IUPAC(2~{S})-1-(1,3-benzodioxol-5-yl)-2-(ethylamino)propan-1-one
    SMILESCCNC(C)C(=O)c1ccc2OCOc2c1
    InChIKeyMJEMIOXXNCZZFK-QMMMGPOBSA-N
    Phenethylamines; Cathinones; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Cathinone
    Psychoactive Class Stimulant / Entactogen

    Receptor Profile

    Receptor Actions

    Inhibitors
    Serotonin-dopamine-norepinephrine reuptake inhibitor (SNDRI)
    Other
    Serotonin-dopamine-norepinephrine releasing agent (SNDRA)

    History & Culture

    Ethylone is a synthetic cathinone that represents the β-keto analogue of MDEA, a substance colloquially known as "Eve." The compound has only a brief history of documented human use, with minimal records of consumption prior to its commercial emergence around 2011. In the United States, ethylone began appearing in cathinone products in late 2011, marking the start of its presence in recreational drug markets. As a designer drug, ethylone has been commonly sold alongside other synthetic cathinones such as butylone and 3-MMC. It frequently appears as a substitute or counterfeit product for MDMA and methylone, particularly as methylone's availability on the research chemical market declined. The substance is reported to be less potent than its structural relative methylone. Very little scientific data exists regarding ethylone's properties, and its history of human usage remains notably limited compared to more established entactogens.

    Effect Profile

    Curated + 13 Reports
    Empathogen 6.0

    Strong euphoria with moderate stimulation and sensory enhancement, low empathy

    Empathy / Social Openness×3
    3
    Euphoria / Mood Elevation×2
    10
    Stimulation×1
    7
    Sensory Enhancement×1
    6
    Stimulant 5.4

    Strong euphoria and anxiety/jitters with moderate focus, low stimulation

    Stimulation / Energy×3
    3
    Euphoria / Mood Lift×2
    10
    Focus / Productivity×2
    7
    Anxiety / Jitters×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 4d Baseline ~5d

    Experience Report Analysis

    Erowid
    13 Reports
    2005–2015 Date Range
    10 With Age Data
    9 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 13 experience reports (13 Erowid)

    13 Reports
    9 Effects Detected
    5 Positive
    3 Adverse
    1 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 5

    Stimulation 69.2% 70%
    Euphoria 69.2% 70%
    Music Enhancement 53.8% 70%
    Empathy 46.2% 70%
    Tactile Enhancement 30.8% 70%

    Adverse Effects 3

    Anxiety 30.8% 70%
    Muscle Tension 30.8% 70%
    Headache 23.1% 70%

    Real-World Dose Distribution

    62K Doses

    From 19 individual dose entries

    Oral (n=16)

    Median: 100.0mg 25th: 50.0mg 75th: 150.0mg 90th: 170.0mg
    mg/kg median: 1.55 mg/kg 75th: 2.158

    Form / Preparation

    Most common forms and preparations reported

    Legal Status

    Country Status Notes
    Brazil Illegal Prohibited under Portaria SVS/MS nº 344. Possession, production, and sale are illegal.
    China Controlled Classified as a controlled substance as of October 2015 under national drug control regulations.
    Germany Anlage I BtMG Listed in Anlage I of the Betäubungsmittelgesetz (Narcotics Act, Schedule I) since December 13, 2014. Manufacturing, possession, import, export, purchase, sale, procurement, and dispensing without a license are prohibited.
    Sweden Controlled Classified as a controlled substance since 1992 under Swedish narcotics legislation.
    Switzerland Controlled (Verzeichnis D) Specifically named as a controlled substance under Verzeichnis D of Swiss narcotics legislation.
    United Kingdom Class B Controlled as a Class B substance under the Misuse of Drugs Act 1971 through the cathinone catch-all clause, which encompasses synthetic cathinone derivatives.
    United States Unscheduled Not specifically scheduled under federal law. However, as a structural analogue of methylone and MDMA, it may be prosecuted under the Federal Analogue Act when sold for human consumption.
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