Home
    Disclaimer
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Etoxadrol

    Aliases: Cl-1848c, U-37862a

    Dissociative Research-chemical

    Summary TheDrug.Wiki

    Etoxadrol is a dioxolane NMDA antagonist developed as a dissociative anesthetic; unlike arylcyclohexylamines (PCP/ketamine), it features a 1,3-dioxolane piperidine scaffold. Clinical work shows IV 0.75 mg/kg yields anesthesia averaging 26 minutes (14-53 minutes) with active airway reflexes but raised heart rate/blood pressure and tachypnea. Prominent post-dose phenomena include alternating nystagmus lasting hours and vivid dream-like states; approximately 20% of patients reported unpleasant or threatening dreams persisting up to 24 hours.

    Dose Information TheDrug.Wiki

    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 6.4
    Strong 6/10

    Strong dissociative depth with moderate motor impairment, low mania and insight

    Dissociative Depth ×3
    10
    depersonalization derealization perception of bodily lightness amnesia memory suppression
    ⚠ Mania / Compulsion ×1
    2
    stimulation
    Insight / Novel Thought ×2
    2
    creativity enhancement
    ⚠ Motor / Sensory Impairment ×1
    7
    motor control loss tactile suppression numbness
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Etoxadrol
    View methodology →

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2–4 weeks for noticeable reduction

    Cross-Tolerances

    ketamine
    50%
    PCP analogues
    50%
    other uncompetitive NMDA antagonists
    50%

    Effects TheDrug.Wiki

    Positive
    • Analgesia
    • Stimulation
    • Physical euphoria
    • Stamina enhancement
    • Creativity enhancement
    Negative
    • Nystagmus
    • Tachycardia
    • Nausea
    • Numbness
    • Loss of balance
    Positive
    • Cognitive euphoria
    Negative
    • Amnesia
    • Depersonalization
    • Confusion
    • Anxiety
    • Derealization
    • Motor control loss
    • Memory suppression
    Neutral
    • Dissociation
    • Time distortion
    Positive
    • Perception of bodily lightness
    • Bodily control enhancement
    • Visual acuity enhancement
    Negative
    • Tactile suppression
    • Derealization
    Neutral
    • Dream-like imagery
    • After images
    • Drifting
    • Environmental cubism
    • Environmental orbism

    Combinations TripSit

    Etoxadrol's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki