Flubromazepam Stats & Data
O=C1CN=C(c2ccccc2F)c2cc(Br)ccc2N1ZRKDDZBVSZLOFS-UHFFFAOYSA-NInteraction Warnings
This combination can result in an increased risk of vomiting during unconsciousness and death from the resulting suffocation. If this occurs, users should attempt to fall asleep in the recovery position or have a friend move them into it.
It is dangerous to combine benzodiazepines with stimulants due to the risk of excessive intoxication. Stimulants decrease the sedative effect of benzodiazepines, which is the main factor most people consider when determining their level of intoxication. Once the stimulant wears off, the effects of benzodiazepines will be significantly increased, leading to intensified disinhibition as well as other effects.
Receptor Profile
Receptor Actions
History & Culture
Flubromazepam is a benzodiazepine derivative first synthesized in 1960. Despite being developed during a period of active benzodiazepine research that produced many compounds which would eventually reach clinical use, flubromazepam was never marketed and received no further scientific attention for over fifty years. The compound reemerged in late 2012 when it appeared on the grey market as a novel designer drug. Since then, it has been sold primarily through online research chemical vendors for recreational use and has not undergone formal clinical study. An alternate structural isomer, sometimes referred to as "iso-flubromazepam," has reportedly been sold under the same name during this period.
Subjective Effect Notes
physical: The physical effects of flubromazepam can be broken down into several components which progressively intensify proportional to dosage.
cognitive: The cognitive effects of flubromazepam can be broken down into several components which progressively intensify proportional to dosage. The general head space of flubromazepam is described by many as one of intense sedation and decreased inhibition. It contains a large number of typical depressant cognitive effects.
Effect Profile
Curated + 4 ReportsStrong anxiolysis, cognitive impairment, and euphoria with mild sedation
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Rapid functional tolerance develops with repeated use, as with other GABA-A positive allosteric modulators; recovery is slow. Model parameters are approximate and intended for harm-reduction planning (spacing doses by several days); individual variability is high. Data quality largely anecdotal.
Cross-Tolerances
Experience Report Analysis
ErowidDemographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 4 experience reports (4 Erowid)
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 1
Adverse Effects 1
Real-World Dose Distribution
62K DosesFrom 4 individual dose entries
Form / Preparation
Most common forms and preparations reported
Benzodiazepine Equivalence
Flubromazepam - 6-8mg ~=10mg Diazepam.
Legal Status
| Country | Status | Notes |
|---|---|---|
| Canada | Schedule IV CDSA | Controlled as a benzodiazepine under Schedule IV of the Controlled Drugs and Substances Act. |
| Germany | Anlage II BtMG | Listed in Anlage II of the Betäubungsmittelgesetz (Narcotics Act) since November 21, 2015. Manufacturing, possession, import, export, purchase, sale, procurement, and dispensing are prohibited without a license. |
| Russia | Schedule III | Classified as a Schedule III controlled substance since 2017. |
| Switzerland | Verzeichnis E | Specifically named as a controlled substance under Verzeichnis E of Swiss narcotics regulations. |
| Turkey | Controlled | Classified as a controlled drug under national legislation. Possession, production, supply, and importation are illegal. |
| United Kingdom | Class C | Controlled under the Misuse of Drugs Act 1971 as of May 31, 2017. Possession, production, and supply are prohibited. |
| United States | Unscheduled (Federal); Schedule I (Virginia) | No federal scheduling under the Controlled Substances Act. Virginia has independently classified flubromazepam as a Schedule I controlled substance under state law. |
Harm Reduction
drugs.wikiIdentity confusion and mislabeling have occurred: two positional isomers (“flubromazepam” vs “iso-flubromazepam”) have circulated; use drug checking where possible and avoid assuming pellets/tablets contain accurate doses. The long and variable half-life promotes accumulation—space doses by multiple days and avoid redosing during the same session to prevent unintended multi-day intoxication. Delayed onset (often ≥60 minutes) increases redose temptation; plan a fixed single dose and wait. Strong sedation, psychomotor impairment, anterograde amnesia, and next-day ‘hangover’ are commonly reported—do not drive, cycle, swim, or operate machinery for at least 24 hours after dosing (longer after high doses). Combining with other depressants—especially opioids, alcohol, GHB/GBL or tramadol—markedly increases risk of respiratory depression and fatal overdose; avoid these combinations. If physically dependent, do not abruptly stop: benzodiazepine withdrawal can be severe or life-threatening; taper gradually with clinical guidance. Avoid insufflation or injection: poor solubility and binders increase harm with no benefit; if using powder, prepare a measured solution (e.g., in propylene glycol/ethanol) for volumetric dosing to improve accuracy. Consider pregnancy and neonatal risks: benzodiazepines cross the placenta and may cause neonatal withdrawal; seek medical advice. Given frequent counterfeit/overdosed tablets in the market, prefer known-concentration solutions and send suspect samples to a lab drug-checking service when feasible.
References
Cited References
- Bluelight: Flubromazepam Discussion Thread
- Erowid Experience: An Assessment of Numerous Benzodiazepines
- Hong et al. (2022) - Flubromazepam Cardiotoxicity Study
- Moosmann et al. (2013) - Detection and Identification of Flubromazepam
- Tripsitter: Flubromazepam Harm Reduction Guide
- UK Assessment of NPS Benzodiazepines - Abouchedid et al. (2018)
- WHO Expert Committee: Flubromazepam Critical Review (2024)
- TripSit Factsheet: Flubromazepam
- Bluelight Drug Info: Flubromazepam
- Drug-Do: Benzos
Drugs.wiki References
- IsomerDesign: Flubromazepam (IDs, synonyms, PubChem)
- Erowid Novel Drug Briefs (Flubromazepam overview, early reports)
- TripSit Wiki: Drug combinations (benzodiazepines with opioids/GHB/tramadol marked dangerous)
- TripSit: Benzodiazepine tools and combination chart announcements (HR context)
- EUDA European Drug Report 2024–2025: Benzodiazepines common in overdose; opioid co-use increases risk
- EUDA FAQ: Risk factors for drug-induced deaths (polydrug depressants incl. benzodiazepines)
- DrugWise: Benzodiazepines (withdrawal dangers, driving risk, alcohol/benzo cautions)
- Bluelight: Flubromazepam megathread (reports of long duration, PG solutions; cautions)
- Bluelight: Flubromazepam – 2 types (positional isomer confusion in market)
- Erowid/DrugsData project overview (laboratory drug checking option)