Home
    Disclaimer
    Fluminorex molecular structure

    Fluminorex Stats & Data

    NPS DataHub
    MW230.19
    FormulaC10H9F3N2O
    CAS720-76-3
    IUPAC5-[4-(trifluoromethyl)phenyl]-4,5-dihydro-1,3-oxazol-2-amine
    SMILESNC1=NCC(O1)c1ccc(cc1)C(F)(F)F
    InChIKeyNMGYDYBWRZHLHR-UHFFFAOYSA-N
    Phenethylamines; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Amphetamine
    Psychoactive Class Stimulant
    Half-Life Unknown in humans; qualitatively may be prolonged by para‑CF3 lipophilicity. A cautious working estimate sometimes cited is 8–12 h, but this is unverified.

    Effect Profile

    Curated
    Stimulant 5.6

    Strong anxiety/jitters with moderate stimulation and focus, mild euphoria

    Stimulation / Energy×3
    7
    Euphoria / Mood Lift×2
    5
    Focus / Productivity×2
    7
    Anxiety / Jitters×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki
    Half-Life
    Unknown in humans; qualitatively may be prolonged by para‑CF3 lipophilicity. A cautious working estimate sometimes cited is 8–12 h, but this is unverified.
    Addiction Potential
    High: aminorex-type stimulants show strong dopaminergic reinforcement, rapid tolerance accrual, and compulsive redosing patterns; risk increases with short-interval redosing and rapid-ROA use.

    Tolerance Decay

    Full tolerance 2d Half tolerance 3d Baseline ~10d

    Patterns inferred from stimulant class use (amphetamine/aminorex analogues). Expect rapid tolerance with consecutive days, partial decay over 3–7 days, and near‑baseline after ~10–14 days. Evidence quality: anecdotal/low.

    Cross-Tolerances

    amphetamines
    30% ●○○
    aminorex analogues (e.g., 4‑methylaminorex, cyclazodone, pemoline)
    50% ●○○

    Harm Reduction

    drugs.wiki

    Fluminorex is the para‑trifluoromethyl analogue of aminorex; identity and structure are confirmed in PubChem, but there are no modern human pharmacokinetic data or clinical trials for this compound. Aminorex-class agents (including aminorex itself) have been causally associated with pulmonary arterial hypertension (PAH); mechanistically, aminorex and several anorectics act as serotonin transporter substrates, a property implicated in drug‑induced PAH, so long, repeated, or high‑dose exposure may carry non‑trivial PAH risk even if immediate subjective effects seem benign. Because of this risk, avoid daily or continuous use, set strict cycle limits, and discontinue permanently if unexplained exertional dyspnea, chest pain, syncope, or lower‑extremity edema appear; these warrant medical evaluation for PAH. The aminorex class also releases catecholamines (DAT/NET), so hyperthermia, tachycardia, and hypertension are core dose‑dependent hazards; avoid co‑use with other stimulants and manage environment (cooling, rest breaks) to reduce heat burden. Interaction risk is heightened with monoamine oxidase inhibitors (contraindicated) and with serotonergic agents (SSRIs/SNRIs/releasers/triptans) due to the class’s measurable SERT activity; combinations can precipitate hypertensive or serotonin toxicity even at moderate doses. Dosing guidance here is intentionally conservative and derived from 4‑methylaminorex user summaries (10–25 mg typical) rather than fluminorex trials; begin with threshold dosing and allow full onset before considering any increase, especially with insufflation/vaporisation where impulsive redosing risk is high. Market unfamiliarity means mislabeling is plausible; multi‑reagent kits are only presumptive and can miss adulterants — laboratory analysis (GC‑MS/LC‑MS) through a drug checking service is the most reliable way to confirm identity and detect mixtures. If using despite the above, prioritize oral dosing, spacing sessions by at least 10–14 days, maintain hydration with electrolytes while avoiding over‑hydration, and plan for insomnia with a stimulant‑free sleep window; avoid sedative ‘comedown’ cocktails (e.g., high‑dose alcohol, GHB, benzodiazepines) which carry their own risks.

    ← Back to Fluminorex