Summary
IPPH is a structural analogue of methylphenidate that first appeared on online markets in 2015 following the UK ban on ethylphenidate. It is reported to have fewer physical side effects than methylphenidate, though subjective effects are often described as milder and less euphoric. The compound displays greater dopaminergic activity than adrenergic activity and has a longer duration than methylphenidate due to reduced metabolism by CES1 enzymes. Purity and synthetic impurities may vary between sources. It was banned in the UK in April 2015 and is Schedule III in Canada.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 7-10mg | 10-15mg | 15-30mg | 30mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 20-40 min | 15-30 min | 1-3 hrs | 1-2 hrs | 60-0 min | 180-0 min |
| Insufflated | 5-10 min | 10-20 min | 1-2 hrs | 1-2 hrs | 60-0 min | 180-0 min |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute tolerance; longer for full reset
Effects
Positive
- Stimulation
- Increased energy/alertness
Negative
- Increased heart rate
- Vasoconstriction
- Teeth grinding
- Increased Heart Rate
- Pupil dilation
- Increased perspiration
- Teeth Grinding
- Spontaneous bodily sensations
Positive
- Focus enhancement
- Motivation enhancement
- Analysis enhancement
- Cognitive euphoria
- Wakefulness
Negative
- Compulsive redosing
- Anxiety
- Cognitive fatigue
- Depression
- Irritability
- Thought deceleration
- Thought acceleration
- Time distortion
Positive
- Increased music appreciation
- Increased libido
Negative
- Appetite suppression
- Dehydration
- Light sensitivity
- Appetite Suppression
- Double vision
- Disinhibition
- Increased sexuality
- Visual and auditory hallucinations