Summary
Ketoconazole is a depressant opioid. Reported effects include euphoria, anxiety suppression, muscle relaxation, and compulsive redosing. Limited data is available on its dosage and safety profile.
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk
Effects
Positive
- Physical euphoria
- Muscle relaxation
- Anxiolytic
Negative
- Motor impairment
- Nausea
- Respiratory depression
- Sedation
- Sedative
- Dystaxia
- Itchiness
Positive
- Reduced anxiety
- Anxiety suppression
- Cognitive euphoria
- Euphoria
Negative
- Dizziness
- Compulsive redosing
- Amnesia
- Thought deceleration
- Motor control loss
- Constipation
Positive
- Increased music appreciation
- Increased libido
Negative
- Disinhibition
- Appetite suppression
- Dehydration
- Light sensitivity
- Double vision
- Acuity suppression
- Dulled perception
- Internal hallucinations