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    L-Tryptophan Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 4 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • PubChem toxicity data

    Aliases: tryptophan

    Nootropic Supplement

    Summary Erowid TripSit PsychonautWiki

    L-Tryptophan is an essential amino acid, meaning the human body does not produce it naturally, but is required for the body's healthy functioning. L-Tryptophan is present in a wide range of foods including beans, nuts, milk, and poultry. L-Tryptophan is a precursor to 5-HTP (which is a precursor to serotonin) and is sold as a sleep aid and mood enhancer.

    Dose Information TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 50-100mg 100-300mg 300-500mg 500mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit PsychonautWiki

    ROA Onset Peak Total
    Oral 30-60 min 4-6 hrs 4-6 hrs

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track L-Tryptophan there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "L-Tryptophan (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    L-Tryptophan
    Unit
    mg
    Description 
    L-Tryptophan
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): threshold 25 · light 50-100 · common 100-300 · strong 300-500 · heavy 500+

Oral duration: onset 0.5-1h · peak 4-6h · total 4-6h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 200 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Effects Erowid

    Aggregated from 8 Erowid experience reports

    Positive Effects 2

    Euphoria 50.0% 70%
    Stimulation 37.5% 70%

    Adverse Effects 0

    Combinations

    Cross-Check L-Tryptophan with another substance

    L-Tryptophan's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

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