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    Disclaimer
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    ⚠ Opioids carry significant risk of respiratory depression, physical dependence, and fatal overdose. Never combine with other depressants.

    Levomethorphan

    Aliases: Lvm, Ro 1-5470/6, L-methorphan

    Depressant Research-chemical Opioid

    Summary TheDrug.Wiki

    Levomethorphan is a potent opioid analgesic that has never been marketed pharmaceutically. It is the L-stereoisomer of racemethorphan and acts as a prodrug to levorphanol, being demethylated by liver enzymes to its active form. Approximately five times more potent than morphine, levomethorphan carries significant risks of respiratory depression, addiction, and overdose.

    Dose Information TheDrug.Wiki

    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Comeup Peak Offset After Effects
    Oral 20-60 min 30-90 min 1-3 hrs 4-6 hrs 2-4 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 7.0
    Strong+ 7/10

    Strong euphoria, itching/nausea, and pain relief with low sedation

    Euphoria / Warmth ×3
    10
    physical euphoria euphoria cognitive euphoria mood lift
    Analgesia ×2
    8
    pain relief analgesia
    Sedation / Relaxation ×1
    3
    sedation
    ⚠ Itching / Nausea ×1
    10
    itching nausea constipation dry mouth
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Levomethorphan
    View methodology →

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk

    Effects TheDrug.Wiki

    Positive
    • Pain relief
    • Physical euphoria
    • Analgesia
    Negative
    • Respiratory depression
    • Itching
    • Nausea
    • Dry Mouth
    Neutral
    • Sedation
    • Itchiness
    • Relaxant
    Positive
    • Euphoria
    • Cognitive euphoria
    • Anxiety suppression
    • Mood lift
    • Cognitive Euphoria
    Negative
    • Compulsive redosing
    • Dysphoria
    • Constipation
    • Dizziness
    Neutral
    • Dissociation
    Positive
    • Visual geometry
    Negative
    • Appetite suppression
    • Decreased Libido
    • Appetite Suppression
    • Double vision
    • Spatial disorientation
    Neutral
    • Dulled perception
    • Internal hallucination
    • Internal hallucinations
    • Visual and auditory hallucinations

    Combinations TripSit

    Levomethorphan's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki