Meclofenoxate
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- toxicity data (PsychonautWiki)
- classified Tentative
- 4 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- toxicity data (PsychonautWiki)
- classified Tentative
Aliases: Anp 235, Acephen, Lucidril, Helfergin, Centrophenoxine
Summary
Meclofenoxate is not FDA-approved in the United States but is sold as a dietary supplement; it is a prescription medication in some countries including Japan and parts of Europe. Individuals with depression, mania, epilepsy, or convulsive disorders should avoid use entirely. The substance is prohibited for athletes under WADA regulations as a stimulant.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-200mg | 400-800mg | 800-1000mg | 1000mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 30-90 min | 2-4 hrs | 2-4 hrs | 4-8 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate stimulation and focus with mild anxiety/jitters, low euphoria
Add missing routes to PsychonautWiki Journal
The PsychonautWiki Journal app already has Meclofenoxate, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.
Meclofenoxate: routes the PsychonautWiki Journal app is missing Source: SubstanceSearch (substancesearch.com) Oral duration: onset 0.5-1.5h · peak 2-4h · offset 2-4h · total 4-8h · after-effects 12h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stamina Enhancement
- Stimulation
- Subtle Stimulation
- Increased heart rate
- Headaches
- Fatigue
- Headache
- Teeth grinding
- Gastrointestinal Distress
- Body odor alteration
- Focus Enhancement
- Memory Enhancement
- Wakefulness
- Motivation Enhancement
- Dream Potentiation
- Mindfulness
- Thought Connectivity
- Anxiety Suppression
- Addiction Suppression
- Focus intensification
- Bodily Control Enhancement
- Visual Acuity Enhancement
- Acuity Enhancement
- Auditory Acuity Enhancement
- Color Enhancement
- Light sensitivity
- Appetite Suppression
- Dehydration
- Olfactory Intensification
Helpful Links
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