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    Methaqualone Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 5 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • PubChem toxicity data

    Aliases: 714s, Sopor, Ludes, Quack, Parest, quaaludes, qualudes, mandrax

    Summary PsychonautWiki

    Methaqualone (brand name Quaalude in the US and Mandrax in the UK) is a central nervous system (CNS) depressant of the quinazolinone class that acts as a sedative and hypnotic. The sedative–hypnotic activity of methaqualone was first noted by researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s as a hypnotic, for the treatment of insomnia, and as a sedative and muscle relaxant.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 150-300mg 300-500mg 500-600mg 600mg+
    Smoked 50-100mg 100-200mg 200-300mg 300mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 20-45 min 30-60 min 2-4 hrs 2-4 hrs 6-12 hrs 5-8 hrs
    Smoked 30-45 min - - - 4-6 hrs 1-2 hrs

    Tolerance

    Build-up varies by mechanism; therapeutic tolerance may develop over weeks of regular use
    Reset typically days to weeks after discontinuation

    Tolerance Decay

    Full tolerance 2d Half tolerance 7d Baseline ~14d

    Erowid documents rapid tolerance; tolerance to euphoria rises faster than to respiratory depression, increasing overdose risk when escalating doses. Spacing doses by several days to a week is prudent. Estimates above are approximate and based on HR consensus/user reports, not controlled studies.

    Effects Erowid

    Aggregated from 21 Erowid experience reports

    Positive Effects 8

    Euphoria 57.1% 70%
    Sedation 47.6% 70%
    Body High 28.6% 70%
    Stimulation 28.6% 70%
    Empathy 23.8% 70%
    Color Enhancement 14.3% 70%
    Tactile Enhancement 14.3% 70%
    Anxiety Suppression 14.3% 70%

    Adverse Effects 3

    Motor Impairment 42.9% 70%
    Confusion 19.0% 70%
    Nausea 14.3% 70%

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 1 positive 6 neutral 1 cautionary visit
    A Pleasant Surprise, Overall Lovely Compound positive exp #115456

    A Pleasant Surprise and Glowing Experience This experience took place in my residence, where I was undisturbed. To preface I have been searching for Methaqualone for quite some time, though like many newer researchers I assumed I would never have the opportunity to try it given its production history.

    Fishy · 293 mg oral / vaporized / repeated vaporized / repeated
    Synthesis and Effects neutral exp #114521

    Methaqualone About 10 years ago I was able to acquire some ortho-toluidine from which I made a number of small batches of Methaqualone. The synthesis went basicly as described by cheapskate on the net.

    Qual · 200 - 1000 mg oral / repeated smoked
    Quaaland neutral exp #23677

    FEW QUICK NOTES I’ve noticed the last time I submitted a report for Quaaludes that I was only the second submitter. I wanted to change that. There aren’t enough reports on methaqualone. Especially, there aren’t any reports for methaqualone alone [INTRODUCTION + PART 1].

    Blazed · 300 mg oral
    I Was In Heaven neutral exp #24492

    I was home alone, looking for something to do. Since being home alone is very unusual for me, I usually do some sort of illicit substance. However, I was tapped out of every substance I usually have. I searched my brother's and sister's rooms, but, alas, I couldn't find anything.

    Name Taken · 300 mg oral / 300 mg oral
    Quaaduds Deadludes ...or Not.... neutral exp #105008

    At the time of writing this, it’s been about 5 hours since first ingesting the first capsule (300mg). My friends and I recently acquired Methaqualone powder, and were beyond excited to try out this ‘legendary’ drug.

    ImaTryItOut · 300 mg oral / 1 shot oral / 100 mg insufflated / 200 mg oral
    The Best He Had Ever Felt neutral exp #35368

    I did not have a lot of experience with Quaaludes when they were legal (1961 - 1984 or during the bootleg period of 1984 - 1988). I had taken them a few times, but in all likelyhood the ones I had taken over a decade ago were most likely large doses of Valium (diazapam).

    MobiusDick · 450 mg oral
    A Thorough Exploration neutral exp #115836

    Having a good friend of mine who is a talented organic chemist, I have had the opportunity to thoroughly experiment with Methaqualone (Quaalude) over the last 2 years. The material was LCMS tested and was in excess of 99% purity and the real deal, not some RC analogue.

    Cellophane · 150 - 400 mg oral / repeated smoked
    Smoke Of God Or Satan? cautionary exp #20671

    Where I come from, South Africa, this drug is not taken orally as it's done in the rest of the world our country has a much more interesting aproach, smoking it. Methaqualone or Mandrax as it is reffered to here is the most used drug in South Africa.

    exp · 0.5 tablets smoked
    Bluelight 2 threads 2 neutral visit
    Methaqualone First Time An Experience With Quaalude Methaqualone neutral

    I figured I'd write up a little something, because before I took my first pill last night, I struggled to find many accounts of the experience (likely due to the rarity of the drug). Thus, I figured I'd share my experience and bring some insight to the masses.

    scraped 2026-03-14

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