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    Methaqualone

    Aliases: 714s, Sopor, Ludes, Quack, Parest, quaaludes, qualudes, mandrax

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    Methaqualone structure

    Summary PsychonautWiki

    Methaqualone (brand name Quaalude in the US and Mandrax in the UK) is a central nervous system (CNS) depressant of the quinazolinone class that acts as a sedative and hypnotic. The sedative–hypnotic activity of methaqualone was first noted by researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s as a hypnotic, for the treatment of insomnia, and as a sedative and muscle relaxant. It is still produced and used clandestinely as a recreational drug throughout the world. The drug was popular in the 1970s with hippies and in the disco club scene, known as ludes (from "quaaludes") or disco biscuits.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 150-300mg 300-500mg 500-600mg 300mg+
    Smoked 50-100mg 100-200mg 200-300mg 300mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 20-45 min 30-60 min 2-4 hrs 2-4 hrs 6-12 hrs 300-0 min
    Smoked 1800-0 min - - - 240-0 min 3600-0 min

    Tolerance

    Build-up varies by mechanism; therapeutic tolerance may develop over weeks of regular use
    Reset typically days to weeks after discontinuation

    Effects TheDrug.Wiki TripSit

    Positive
    • Physical euphoria
    • Muscle relaxation
    • Anxiolytic
    • Muscle Relaxant
    Negative
    • Respiratory depression
    Neutral
    • Sedation
    • Impaired coordination
    • Slurred speech
    • Sedative
    • Dystaxia
    • Hypnotic
    Positive
    • Cognitive euphoria
    • Anxiety suppression
    • Dream potentiation
    Negative
    • Thought deceleration
    • Motor control loss
    • Compulsive redosing
    • Amnesia
    • Constipation
    • Dizziness
    • Information processing suppression
    Neutral
    • Subconscious communication
    Positive
    • Increased libido
    • Tactile enhancement
    Negative
    • Disinhibition
    • Acuity suppression
    • Double vision
    Neutral
    • Visual disconnection
    • Internal hallucination
    • Changes in gravity
    • Internal hallucinations
    • Dulled perception

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