Methazolamide
Summary
Methazolamide is a depressant benzodiazepine. Reported effects include euphoria, anxiety suppression, muscle relaxation, and compulsive redosing. Limited data is available on its dosage and safety profile.
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Benzodiazepine
7.6
Intense
8/10
Strong anxiolysis and euphoria with moderate cognitive impairment, mild sedation
Anxiolysis
×3
10
anxiety suppression
anxiolytic
reduced anxiety
muscle relaxation
Sedation / Relaxation
×2
5
sedation
muscle relaxation
Motor / Cognitive Impairment
×1
7
motor control loss
amnesia
double vision
Euphoria / Mood Lift
×1
10
cognitive euphoria
euphoria
physical euphoria
disinhibition
Based on reports from:
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Tolerance Decay
Full tolerance
3d
Half tolerance
37d
Baseline
~60d
Effects
Positive
- Physical euphoria
- Muscle relaxation
- Anxiolytic
Negative
- Motor impairment
- Nausea
- Respiratory depression
- Sedation
- Sedative
- Dystaxia
- Itchiness
Positive
- Reduced anxiety
- Anxiety suppression
- Cognitive euphoria
- Euphoria
Negative
- Dizziness
- Compulsive redosing
- Amnesia
- Thought deceleration
- Motor control loss
- Constipation
Positive
- Increased music appreciation
- Increased libido
Negative
- Disinhibition
- Appetite suppression
- Dehydration
- Light sensitivity
- Double vision
- Acuity suppression
- Dulled perception
- Internal hallucinations
Combinations
Pill Identifiers
6
known pill identifiers on record — view imprints, colors, shapes, and images
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Methazolamide's nerd page
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