Summary
Myristicin is a naturally-occurring deliriant substance of the phenylpropene class. It is present in small amounts in the essential oil of nutmeg and, to a lesser extent, in other spices such as parsley and dill. It has been shown to act on the endocannabinoid system.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-200mg | 200-500mg | 500-800mg | 800mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 3-8 hrs | 1-4 hrs | 9-12 hrs | 12-48 hrs | 24-72 hrs |
Tolerance
Build-up
develops over weeks of regular use via CB1 receptor downregulation
Reset
2–4 weeks for most users; heavy users may need longer
Effects
Positive
- Pain relief
- Anxiolysis
Negative
- Nausea
- Dry mouth
- Increased heart rate
- Tachycardia
- Nausea/vomiting
- Sedation
- Spontaneous bodily sensations
- Vasodilation
Positive
- Euphoria
- Anxiety suppression
- Thought connectivity
- Reduced anxiety
Negative
- Anxiety
- Paranoia
- Motor control loss
- Short-term memory suppression
- Psychosis
- Time distortion
Positive
- Color enhancement
- Increased music appreciation
- Appetite enhancement
- Auditory acuity enhancement
Negative
- Dehydration
- Dulled perception
- Visual distortions
- Appetite intensification
- Changes in felt gravity
- Perception of bodily heaviness