N-Acetylcysteine
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Encyclopedic
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- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
Aliases: Nac, Acetylcysteine
Summary
N-Acetylcysteine (NAC), also known as Acetylcysteine, is a medication that is used to treat paracetamol (acetaminophen) overdose, and to loosen thick mucus in individuals with chronic bronchopulmonary disorders like pneumonia, bronchitis and cystic fibrosis. It has been used to treat lactobezoar in infants. It can be taken intravenously, by mouth, or inhaled as a mist.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 400-600mg | 600-1000mg | 1000-1500mg | 1500mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 20-60 min | 1-3 hrs | 2-4 hrs | 3-6 hrs |
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Bronchodilation
- Cough Suppression
- Stimulation
- Nausea
- Headaches
- Increased Blood Pressure
- Increased heart rate
- Headache
- Itchiness
- Sedation
- Addiction Suppression
- Anxiety Suppression
- Focus Enhancement
- Motivation Enhancement
- Mindfulness
- Cognitive Clarity
- Wakefulness
- Motivation enhancement
- Focus enhancement
- Anxiety
- Increased music appreciation
- Increased libido
- Increased Music Appreciation
- Color enhancement
- Appetite Suppression
- Dehydration
- Light sensitivity
- Appetite suppression
- Dulled perception
- Spontaneous physical sensations
Helpful Links
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