Summary
An analogue of GABA that does pass the brain blood barrier, which is then hydrolyzed into GABA and Niacin. In which the GABA could produce an anxiolytic effect. The Niacin as a vasodilator. And is usually used as part of a nootropic stack.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 40-80mg | 80-140mg | 140-250mg | 250mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | After Effects | Total |
|---|---|---|---|---|
| Oral | 10-45 min | 2.0-4.0 hrs | 1.0-12.0 hrs | 120-0 min |
Tolerance
Build-up
develops over weeks of regular use via CB1 receptor downregulation
Reset
2–4 weeks for most users; heavy users may need longer
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Motor impairment
- Increased heart rate
- Nausea
- Headache
- Headaches
- Insomnia
- Vasoconstriction
- Sedation
Positive
- Reduced anxiety
- Wakefulness
- Motivation enhancement
- Focus enhancement
- Memory enhancement
- Anxiety suppression
- Cognitive euphoria
- Focus Enhancement
Negative
- Anxiety
- Irritability
Positive
- Increased music appreciation
- Increased libido
- Increased Music Appreciation
- Color enhancement
Negative
- Light sensitivity
- Appetite suppression
- Dehydration
- Appetite Suppression
- Dulled perception
- Spontaneous physical sensations