Pipradrol
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 1 source
- 1 ROA with full dose ladder
- duration data present
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Meratran, Alertonic
Summary
Pipradrol was developed in the 1940s for treating depression, ADHD, narcolepsy, and obesity. Its long duration (8-12 hours) can cause severe insomnia if dosed late. Unlike amphetamines, it exhibits more selective action on higher brain centers without significantly affecting blood pressure or respiration.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1mg | 2-4mg | 5-10mg | 10mg |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 15-60 min | 1-3 hrs | 4-8 hrs | 6-12 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria and anxiety/jitters with moderate focus and stimulation
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
No formal human tolerance kinetics identified for pipradrol. Pattern is inferred from stimulant class: repeated frequent dosing over 1–3 days noticeably reduces effect, with partial reversal after several days abstinence; full return toward baseline typically within 1–2 weeks. Treat as anecdotal/theoretical and avoid back-to-back days to limit escalation.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Insomnia
- Tachycardia
- Increased heart rate
- Increased perspiration
- Teeth grinding
- Vasoconstriction
- Sweating
- Jaw clenching
- Wakefulness
- Focus enhancement
- Alertness enhancement
- Euphoria
- Cognitive euphoria
- Motivation enhancement
- Increased sociability
- Anxiety
- Thought acceleration
- Talkativeness
- Increased music appreciation
- Tactile enhancement
- Color enhancement
- Mild visual enhancement
- Increased libido
- Music appreciation
- Appetite suppression
- Light sensitivity
- Disinhibition
- Dehydration
Helpful Links
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