Pipradrol
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Meratran, Alertonic
Summary
Pipradrol was developed in the 1940s for treating depression, ADHD, narcolepsy, and obesity. Its long duration (8-12 hours) can cause severe insomnia if dosed late. Unlike amphetamines, it exhibits more selective action on higher brain centers without significantly affecting blood pressure or respiration.
Dose Information
Dose basis. Potent at low milligram doses; historical Meratran tablets were 1 mg, implying high potency. Use a calibrated 0.001 g scale and consider volumetric dosing. Numbers below are aggregated from user reports and legacy materials; start low, avoid redosing until full effects are clear. Evidence quality: low/anecdotal. Insufflation is not recommended due to long stimulation, mucosal irritation risks, and limited data. If attempted despite advice, use markedly lower-than-oral amounts and expect prolonged insomnia; avoid repeated lines. Evidence quality: anecdotal. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1mg | 2-4mg | 5-10mg | 10mg |
Onset, Duration & After-effects
| ROA | Onset | Offset | Total |
|---|---|---|---|
| Oral | 15-60 min | 4-8 hrs | 6-12 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria and anxiety/jitters with moderate focus and stimulation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Pipradrol there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Pipradrol Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 0.5 · light 1 · common 2-4 · strong 5-10 · heavy 10 Oral duration: onset 0.25-1h · offset 4-8h · total 6-12h · after-effects 6-24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 3 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
No formal human tolerance kinetics identified for pipradrol. Pattern is inferred from stimulant class: repeated frequent dosing over 1–3 days noticeably reduces effect, with partial reversal after several days abstinence; full return toward baseline typically within 1–2 weeks. Treat as anecdotal/theoretical and avoid back-to-back days to limit escalation.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Insomnia
- Tachycardia
- Increased heart rate
- Increased perspiration
- Teeth grinding
- Vasoconstriction
- Sweating
- Jaw clenching
- Wakefulness
- Focus enhancement
- Alertness enhancement
- Euphoria
- Cognitive euphoria
- Motivation enhancement
- Increased sociability
- Anxiety
- Thought acceleration
- Talkativeness
- Increased music appreciation
- Tactile enhancement
- Color enhancement
- Mild visual enhancement
- Increased libido
- Music appreciation
- Appetite suppression
- Light sensitivity
- Disinhibition
- Dehydration
Helpful Links
Report an issue or suggest an edit
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