Summary
Tetrahydrocannabiphorol (THCP) is a potent phytocannabinoid that is structurally similar to delta-9-THC, the main psychoactive compound in cannabis. Like THC, THCP is a CB1 and CB2 receptor agonist with psychoactive effects. Initial in-vitro binding assay studies suggest that THCP may be up to 30 times more potent than delta-9-THC, potentially leading to more pronounced psychoactive effects. However, the full extent of THCP's psychoactivity and how it compares to THC is still being researched.
Tolerance
Build-up
develops over weeks of regular use via CB1 receptor downregulation
Reset
2–4 weeks for most users; heavy users may need longer
Effects
Positive
- Pain relief
- Anxiolysis
Negative
- Nausea
- Dry mouth
- Increased heart rate
- Tachycardia
- Nausea/vomiting
- Sedation
- Spontaneous bodily sensations
- Vasodilation
Positive
- Euphoria
- Anxiety suppression
- Thought connectivity
- Reduced anxiety
Negative
- Anxiety
- Paranoia
- Motor control loss
- Short-term memory suppression
- Psychosis
- Time distortion
Positive
- Color enhancement
- Increased music appreciation
- Appetite enhancement
- Auditory acuity enhancement
Negative
- Dehydration
- Dulled perception
- Visual distortions
- Appetite intensification
- Changes in felt gravity
- Perception of bodily heaviness