Trazodone
Aliases: Trazon, Desyrel, Oleptro, Donaren, Raldesy
Summary
Trazodone is primarily prescribed as an antidepressant and for its anxiolytic and sedative properties, with widespread off-label use for insomnia at lower doses (25-100 mg). Common side effects include drowsiness, orthostatic hypotension, dry mouth, and dizziness. Rare but serious side effects include priapism (prolonged erection requiring immediate medical attention), serotonin syndrome when combined with other serotonergic drugs, and QT interval prolongation.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 25-50mg | 50-100mg | 100-150mg | 150mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-60 min | 1-2 hrs | 1-3 hrs | 3-6 hrs | 5.5-12 hrs |
Tolerance
Build-up
develops over 1–4 weeks of regular use
Reset
days to weeks depending on duration of use
Effects
Aggregated from 60 Erowid experience reports
Positive Effects 9
Stimulation
45.0%
70%
Sedation
38.3%
70%
Anxiety Suppression
28.3%
70%
Color Enhancement
23.3%
70%
Euphoria
13.3%
70%
Focus Enhancement
13.3%
70%
Empathy
11.7%
70%
Music Enhancement
5.0%
70%
Body High
5.0%
70%
Adverse Effects 7
Confusion
18.3%
70%
Headache
13.3%
70%
Nausea
10.0%
70%
Memory Suppression
8.3%
70%
Motor Impairment
5.0%
70%
Increased Heart Rate
5.0%
70%
Sweating
5.0%
70%
Pill Identifiers
32
known pill identifiers on record — view imprints, colors, shapes, and images
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Trazodone's nerd page
Pharmacology, chemical data, effect profiles, and more
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