Viloxazine
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
- classified Tentative
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
- classified Tentative
Aliases: Emovit, Qelbree, Vivalan, Vicilan, Vivarint
Summary
Viloxazine is a selective norepinephrine reuptake inhibitor (NRI) that also modulates serotonergic activity as a 5-HT2B antagonist and 5-HT2C agonist. Originally used as an antidepressant in Europe (1974-2002), it was repurposed and FDA-approved in 2021 for ADHD treatment in the US under the brand name Qelbree. It is generally well-tolerated but may cause insomnia, irritability, somnolence, or gastrointestinal upset.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-75mg | 75-150mg | 150mg+ | - |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 2 hrs | 2-4 hrs | 5 hrs | 12-18 hrs | 3-29 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate stimulation and euphoria
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Viloxazine there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Viloxazine Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 50-75 · common 75-150 · strong 150+ Oral duration: onset 2h · come-up 2-4h · peak 5h · offset 12-18h · total 3-29h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 112.5 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Mild stimulation
- Increased energy
- Stimulation
- Physical euphoria
- Insomnia
- Headache
- Nausea
- Fatigue
- Somnolence
- Decreased appetite
- Reduced hyperactivity
- Reduced impulsivity
- Cognitive euphoria
- Irritability
- Compulsive redosing
- Motor control loss
- Depersonalization
- Improved attention
- Increased focus
- Time distortion
- Increased music appreciation
- Perception of bodily lightness
- Tactile enhancement
- Light sensitivity
- Disinhibition
- Tactile suppression
- Spatial disorientation
- Double vision
- Spontaneous physical sensations
- Visual disconnection
Pill Identifiers
Helpful Links
Report an issue or suggest an edit
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