Viloxazine
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
- classified Tentative
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
- classified Tentative
Aliases: Emovit, Qelbree, Vivalan, Vicilan, Vivarint
Summary
Viloxazine is a selective norepinephrine reuptake inhibitor (NRI) that also modulates serotonergic activity as a 5-HT2B antagonist and 5-HT2C agonist. Originally used as an antidepressant in Europe (1974-2002), it was repurposed and FDA-approved in 2021 for ADHD treatment in the US under the brand name Qelbree. It is generally well-tolerated but may cause insomnia, irritability, somnolence, or gastrointestinal upset.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-75mg | 75-150mg | 150mg | 150mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 2 hrs | 2-4 hrs | 5 hrs | 12-18 hrs | 3-6 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate stimulation and euphoria
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Mild stimulation
- Increased energy
- Stimulation
- Physical euphoria
- Insomnia
- Headache
- Nausea
- Fatigue
- Somnolence
- Decreased appetite
- Reduced hyperactivity
- Reduced impulsivity
- Cognitive euphoria
- Irritability
- Compulsive redosing
- Motor control loss
- Depersonalization
- Improved attention
- Increased focus
- Time distortion
- Increased music appreciation
- Perception of bodily lightness
- Tactile enhancement
- Light sensitivity
- Disinhibition
- Tactile suppression
- Spatial disorientation
- Double vision
- Spontaneous physical sensations
- Visual disconnection
Pill Identifiers
Helpful Links
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