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    Viloxazine

    Aliases: Emovit, Qelbree, Vivalan, Vicilan, Vivarint

    Stimulant Nootropic

    Summary TheDrug.Wiki TripSit

    Viloxazine is a selective norepinephrine reuptake inhibitor (NRI) that also modulates serotonergic activity as a 5-HT2B antagonist and 5-HT2C agonist. Originally used as an antidepressant in Europe (1974-2002), it was repurposed and FDA-approved in 2021 for ADHD treatment in the US under the brand name Qelbree. It is generally well-tolerated but may cause insomnia, irritability, somnolence, or gastrointestinal upset.

    Dose Information TheDrug.Wiki TripSit

    ROA Light Common Strong Heavy
    Oral 50-75mg 75-150mg 150mg 150mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit

    ROA Onset Comeup Peak Offset Total
    Oral 2-2 hrs 2-4 hrs 5-5 hrs 12-18 hrs 21-29 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 5.4
    Moderate+ 5/10

    Moderate stimulation and euphoria

    Stimulation / Energy ×3
    7
    increased energy stimulation mild stimulation
    Euphoria / Mood Lift ×2
    6
    physical euphoria cognitive euphoria
    Focus / Productivity ×2
    0
    ⚠ Anxiety / Jitters ×1
    0
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Viloxazine
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Effects TheDrug.Wiki

    Positive
    • Mild stimulation
    • Increased energy
    • Stimulation
    • Physical euphoria
    Negative
    • Insomnia
    • Headache
    • Nausea
    • Fatigue
    Neutral
    • Somnolence
    • Decreased appetite
    Positive
    • Reduced hyperactivity
    • Reduced impulsivity
    • Cognitive euphoria
    Negative
    • Irritability
    • Compulsive redosing
    • Motor control loss
    • Depersonalization
    Neutral
    • Improved attention
    • Increased focus
    • Time distortion
    Positive
    • Increased music appreciation
    • Perception of bodily lightness
    • Tactile enhancement
    Negative
    • Light sensitivity
    • Disinhibition
    • Tactile suppression
    • Spatial disorientation
    • Double vision
    Neutral
    • Spontaneous physical sensations
    • Visual disconnection

    Pill Identifiers

    2 known pill identifiers on record — view imprints, colors, shapes, and images
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    Viloxazine's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    💊 Pill Identifier 📘 Experience Reports 📖 TheDrug.Wiki 📖 TripSit 📖 PsychonautWiki