Xanthines
Summary
Xanthines (also known as substituted xanthines) are a chemical class of psychoactive substances derived from xanthine, an organic compound found in most human body tissues and fluids as well as in other organisms. Examples of xanthines include caffeine and theobromine. These are commonly used for their effects as both stimulants and bronchodilators.
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
6.5
Strong
6/10
Strong euphoria and anxiety/jitters with moderate focus and stimulation
Stimulation / Energy
×3
6
stimulation
wakefulness
alertness enhancement
Euphoria / Mood Lift
×2
10
physical euphoria
euphoria
cognitive euphoria
motivation enhancement
Focus / Productivity
×2
7
focus enhancement
motivation enhancement
thought acceleration
Anxiety / Jitters
×1
10
anxiety
increased heart rate
teeth grinding
vasoconstriction
Based on reports from:
Tolerance
Build-up
develops rapidly after a single use (serotonergic psychedelic)
Reset
7–14 days for baseline
Tolerance Decay
Full tolerance
1h
Half tolerance
10d
Baseline
~14d
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Increased heart rate
- Vasoconstriction
- Insomnia
- Nausea
- Teeth grinding
- Pupil dilation
- Increased perspiration
- Decreased appetite
Positive
- Alertness enhancement
- Euphoria
- Wakefulness
- Cognitive euphoria
- Motivation enhancement
- Focus enhancement
Negative
- Anxiety
- Talkativeness
- Time distortion
- Thought acceleration
Positive
- Increased music appreciation
- Tactile enhancement
- Increased libido
- Color enhancement
Negative
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Drifting
- Dulled perception
Xanthines's nerd page
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