Sources & Credits
Substance Search is an open-source project that stands on the shoulders of the harm-reduction communities and scientific databases below. The encyclopedia is assembled from these sources for educational and harm-reduction purposes; we are grateful to every one of them. See the Disclaimer for how to use this information safely.
Pharmacology, dosing & interactions
PsychonautWiki
The backbone of our pharmacology: dose-tier tables, durations, routes of administration, half-lives, tolerance curves and drug-interaction data.
psychonautwiki.org
TripSit
Powers the Cross-Check combination-safety ratings (combo.tripsit.me), plus concise factsheets and route references.
tripsit.meDrugBank
Clinical pharmacology and interaction data for approved pharmaceutical drugs.
go.drugbank.comTripsitter
Harm-reduction knowledge-base articles, used to cross-check dosing during our audits.
tripsitter.com
The Drug Users Bible
Dominic Milton Trott’s first-hand harm-reduction reference cataloguing dosages, durations and safety notes across a wide range of substances.
drugusersbible.orgDrugs.Wiki
Structured medical, history and legality notes per substance (community snapshot), by Dilemma.
github.com/Di-lemmadose.wiki
One of our largest contributors of dose ladders, durations and subjective-effect write-ups, released under CC0 (public domain). Its Subjective Effect Index is the work of Josie Kins; each write-up carries its own “Forked from Subjective Effect Documentation by Josie Kins” credit on the substance page. (The same body of work became PsychonautWiki’s Subjective Effect Index.)
dose.wikiGuide to PHARMACOLOGY
The IUPHAR/BPS expert-curated database of what binds what, and how tightly. Powers the Receptor pharmacology table on substance pages — 1,773 measured binding and functional records across 421 substances, each citing the paper it came from. Matched to our catalogue by chemical structure (InChIKey), never by name. Licensed CC BY-SA 4.0.
guidetopharmacology.orgChemistry & molecular identity
PubChem
Every chemistry box — molecular formula, weight, SMILES, InChIKey, IUPAC name and logP — plus toxicity and pharmacokinetic summaries.
pubchem.ncbi.nlm.nih.gov
Isomer Design
Chemical-structure and isomer-relationship data, and an online home for the Shulgin indexes.
isomerdesign.comExperience reports & community
Erowid
Tens of thousands of first-hand Experience Vault reports — the bedrock of our trip-report corpus.
erowid.orgBluelight
Forum thread excerpts and a curated per-substance reference guide from one of the oldest harm-reduction communities.
bluelight.orgCommunity trip reports from r/tripreports, drug-specific subreddits and trip-index archives.
reddit.com
Nervewing
Detailed substance write-ups and conclusions from the Nervewing harm-reduction blog.
nervewing.blogspot.comEffects & qualitative writing
Effectindex
The Subjective Effect Index — the taxonomy and descriptions behind our effect profiles.
effectindex.com
PiHKAL
“Phenethylamines i Have Known And Loved” — Alexander & Ann Shulgin’s foundational work on phenethylamine chemistry and qualitative dosage commentary.
erowid.org
TiHKAL
“Tryptamines i Have Known And Loved” — the Shulgins’ companion volume on tryptamine chemistry and effects.
erowid.orgGeneral reference
Substance Search is a free, open-source harm-reduction encyclopedia. Brand names, logos and marks belong to their respective owners and appear here only to credit the data they make available. To correct or remove a credit, reach out via GitHub — or input feedback on any individual substance page using its “Report / suggest an edit” form.