Sources & Credits

Substance Search is an open-source project that stands on the shoulders of the harm-reduction communities and scientific databases below. The encyclopedia is assembled from these sources for educational and harm-reduction purposes; we are grateful to every one of them. See the Disclaimer for how to use this information safely.

Pharmacology, dosing & interactions

PsychonautWiki

The backbone of our pharmacology: dose-tier tables, durations, routes of administration, half-lives, tolerance curves and drug-interaction data.

psychonautwiki.org

TripSit

Powers the Cross-Check combination-safety ratings (combo.tripsit.me), plus concise factsheets and route references.

tripsit.me

DrugBank

Clinical pharmacology and interaction data for approved pharmaceutical drugs.

go.drugbank.com

Tripsitter

Harm-reduction knowledge-base articles, used to cross-check dosing during our audits.

tripsitter.com

The Drug Users Bible

Dominic Milton Trott’s first-hand harm-reduction reference cataloguing dosages, durations and safety notes across a wide range of substances.

drugusersbible.org

WHO ATC/DDD Index

Defined Daily Dose reference tiers for pharmaceutical substances.

whocc.no

Drugs.Wiki

Structured medical, history and legality notes per substance (community snapshot).

github.com/Di-lemma

SubstanceIndex

Cross-reference name normalisation and supplementary dose / duration data.

Chemistry & molecular identity

PubChem

Every chemistry box — molecular formula, weight, SMILES, InChIKey, IUPAC name and logP — plus toxicity and pharmacokinetic summaries.

pubchem.ncbi.nlm.nih.gov

Isomer Design

Chemical-structure and isomer-relationship data, and an online home for the Shulgin indexes.

isomerdesign.com

NPS Data Hub

Analytical identifiers and metadata for novel psychoactive substances.

nps-datahub.com

Experience reports & community

Erowid

Tens of thousands of first-hand Experience Vault reports — the bedrock of our trip-report corpus.

erowid.org

Bluelight

Forum thread excerpts and a curated per-substance reference guide from one of the oldest harm-reduction communities.

bluelight.org

Community trip reports from r/tripreports, drug-specific subreddits and trip-index archives.

reddit.com

Nervewing

Detailed substance write-ups and conclusions from the Nervewing harm-reduction blog.

nervewing.blogspot.com

Effects & qualitative writing

Effectindex

The Subjective Effect Index — the taxonomy and descriptions behind our effect profiles.

effectindex.com

PiHKAL

“Phenethylamines i Have Known And Loved” — Alexander & Ann Shulgin’s foundational work on phenethylamine chemistry and qualitative dosage commentary.

erowid.org

TiHKAL

“Tryptamines i Have Known And Loved” — the Shulgins’ companion volume on tryptamine chemistry and effects.

erowid.org

General reference

Wikipedia

General background, history and identity information.

en.wikipedia.org

U.S. FDA

US drug-approval records and labelling for pharmaceutical substances.

fda.gov

Substance Search is a free, open-source harm-reduction encyclopedia. Brand names, logos and marks belong to their respective owners and appear here only to credit the data they make available. To correct or remove a credit, reach out via GitHub — or input feedback on any individual substance page using its “Report / suggest an edit” form.