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    Sources & Credits

    Substance Search is an open-source project that stands on the shoulders of the harm-reduction communities and scientific databases below. The encyclopedia is assembled from these sources for educational and harm-reduction purposes; we are grateful to every one of them. See the Disclaimer for how to use this information safely.

    Pharmacology, dosing & interactions

    PsychonautWiki

    The backbone of our pharmacology: dose-tier tables, durations, routes of administration, half-lives, tolerance curves and drug-interaction data.

    psychonautwiki.org

    TripSit

    Powers the Cross-Check combination-safety ratings (combo.tripsit.me), plus concise factsheets and route references.

    tripsit.me

    DrugBank

    Clinical pharmacology and interaction data for approved pharmaceutical drugs.

    go.drugbank.com

    Tripsitter

    Harm-reduction knowledge-base articles, used to cross-check dosing during our audits.

    tripsitter.com

    The Drug Users Bible

    Dominic Milton Trott’s first-hand harm-reduction reference cataloguing dosages, durations and safety notes across a wide range of substances.

    drugusersbible.org

    WHO ATC/DDD Index

    Defined Daily Dose reference tiers for pharmaceutical substances.

    whocc.no

    Drugs.Wiki

    Structured medical, history and legality notes per substance (community snapshot), by Dilemma.

    github.com/Di-lemma

    dose.wiki

    One of our largest contributors of dose ladders, durations and subjective-effect write-ups, released under CC0 (public domain). Its Subjective Effect Index is the work of Josie Kins; each write-up carries its own “Forked from Subjective Effect Documentation by Josie Kins” credit on the substance page. (The same body of work became PsychonautWiki’s Subjective Effect Index.)

    dose.wiki

    Guide to PHARMACOLOGY

    The IUPHAR/BPS expert-curated database of what binds what, and how tightly. Powers the Receptor pharmacology table on substance pages — 1,773 measured binding and functional records across 421 substances, each citing the paper it came from. Matched to our catalogue by chemical structure (InChIKey), never by name. Licensed CC BY-SA 4.0.

    guidetopharmacology.org

    Chemistry & molecular identity

    PubChem

    Every chemistry box — molecular formula, weight, SMILES, InChIKey, IUPAC name and logP — plus toxicity and pharmacokinetic summaries.

    pubchem.ncbi.nlm.nih.gov

    Isomer Design

    Chemical-structure and isomer-relationship data, and an online home for the Shulgin indexes.

    isomerdesign.com

    NPS Data Hub

    Analytical identifiers and metadata for novel psychoactive substances.

    nps-datahub.com

    Experience reports & community

    Erowid

    Tens of thousands of first-hand Experience Vault reports — the bedrock of our trip-report corpus.

    erowid.org

    Bluelight

    Forum thread excerpts and a curated per-substance reference guide from one of the oldest harm-reduction communities.

    bluelight.org

    Reddit

    Community trip reports from r/tripreports, drug-specific subreddits and trip-index archives.

    reddit.com

    Nervewing

    Detailed substance write-ups and conclusions from the Nervewing harm-reduction blog.

    nervewing.blogspot.com

    Effects & qualitative writing

    Effectindex

    The Subjective Effect Index — the taxonomy and descriptions behind our effect profiles.

    effectindex.com

    PiHKAL

    “Phenethylamines i Have Known And Loved” — Alexander & Ann Shulgin’s foundational work on phenethylamine chemistry and qualitative dosage commentary.

    erowid.org

    TiHKAL

    “Tryptamines i Have Known And Loved” — the Shulgins’ companion volume on tryptamine chemistry and effects.

    erowid.org

    General reference

    Wikipedia

    General background, history and identity information.

    en.wikipedia.org

    U.S. FDA

    US drug-approval records and labelling for pharmaceutical substances.

    fda.gov

    Substance Search is a free, open-source harm-reduction encyclopedia. Brand names, logos and marks belong to their respective owners and appear here only to credit the data they make available. To correct or remove a credit, reach out via GitHub — or input feedback on any individual substance page using its “Report / suggest an edit” form.