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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    1cP-LSD Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 5 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • 19 combo interactions documented
    • PubChem toxicity data
    • classified Tentative
    • classified Research-chemical

    Aliases: 1cp, Curie, 1-cpa-lsd, 1-cyclopropanoyl-lsd, 1cplsd

    Summary TheDrug.Wiki TripSit PsychonautWiki

    1cP-LSD (1-cyclopropionyl-lysergic acid diethylamide) is an N-1 acylated prodrug that rapidly hydrolyzes to LSD in human serum, producing essentially identical pharmacology to LSD-25. Potency is approximately equivalent to LSD by weight, with most users reporting indistinguishable effects at standard doses. Use reagent testing (Ehrlich or Hofmann) on all batches to ensure authenticity and rule out NBOMe compounds or DOx substances.

    Perspectives

    “1cP-LSD now stands as one of my favorite lysergamides, second only to LSD itself. Most notable about this compound was that it was extremely visual relative to other lysergamides while remaining very lucid and coherent. There was little body load or overwhelming stimulation.”

    “Despite the limited dose this was a good experience. I felt that it was slightly stronger than 1P, with subtle but noticeable differences throughout, and there did seem to be more clarity in parts; perhaps greater control.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 25-75Β΅g 75-150Β΅g 150-300Β΅g 300Β΅g+
    Sublingual 25-75Β΅g 75-150Β΅g 150-300Β΅g 300Β΅g+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-60 min 0.75-2 hrs 3-5 hrs 3-5 hrs 6-24 hrs 8-10 hrs
    Sublingual 19-60 min 0.75-2 hrs 3-5 hrs 3-5 hrs 6-24 hrs 8-10 hrs

    Effect Profile

    11 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 9.2
    Intense+ 9/10

    Strong visuals, headspace, and auditory effects with moderate body load

    Visual Intensity ×3
    10
    color enhancement drifting tracers synaesthesia pattern recognition enhancement scenery slicing +4 more
    Headspace Depth ×3
    10
    conceptual thinking introspection enhancement personal meaning enhancement recursion emotion enhancement personal bias suppression +1 more
    Auditory Effects ×1
    10
    auditory enhancement music enhancement auditory distortion auditory hallucination synaesthesia
    Body Load / Somatic Effects ×1
    6
    nausea vasoconstriction increased heart rate

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~14d

    Empirical user reports suggest marked tolerance next day with partial recovery over 7–14 days; values are indicative and individualized. Redosing same day extends duration more than intensity.

    Effects Erowid

    Aggregated from 11 Erowid experience reports

    Positive Effects 8

    Color Enhancement 72.7% 70%
    Music Enhancement 72.7% 70%
    Stimulation 63.6% 70%
    Euphoria 54.5% 70%
    Tactile Enhancement 45.5% 70%
    Body High 45.5% 70%
    Empathy 36.4% 70%
    Introspection 27.3% 70%

    Adverse Effects 7

    Anxiety 63.6% 70%
    Nausea 54.5% 70%
    Muscle Tension 36.4% 70%
    Jaw Clenching 27.3% 70%
    Confusion 27.3% 70%
    Pupil Dilation 27.3% 70%
    Thought Loops 27.3% 70%

    Combinations TripSit

    Cross-Check 1cP-LSD with another substance

    Trip Reports Effect Index

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 6 neutral 2 cautionary visit
    A Fire Across the Country, a Garden of Visuals neutral exp #114498

    I want to preface this report with a statement- In a country where drugs are illegal and enforcement of drug laws is largely predicated on race, doing drugs is NOT apolitical.

    nervewing · 150 ug oral / smoked
    I Felt More Grounded in the Present Moment neutral exp #114623

    Boxing the Experience After the small 25ug experiment with this substance in which I made sure that the effects were felt and that they were safe I went on and had a standard trip, some 2 weeks after the LSA one, in order to allow the tolerance to reset.

    c9 · 75 ug oral
    In Which I Become a Little Amazon Indian neutral exp #113721

    At 5:00 pm yesterday, I dropped 300ΞΌg of the new "Curie" analogue, 1cP-LSD. I didn't know what to expect, whether it would be similar to 1p-LSD. The comeup was gradual, taking about 1.5hrs, and I experienced no bodyload at all, no nausea or weirdness.

    rasputin1963
    Everything at Once neutral exp #114597

    Just recently decided to leave my old job after about 5 yrs and decided to celebrate by dropping a few tabs. I have done LSD prior and felt I was fairly well acquainted with the effects. Ate an early dinner then lounged around for a bit waiting till I was ready to dose.

    RxP · 100 ug oral / 200 ug oral / 2 oral / 1 bowl smoked
    Six Times With Different People neutral exp #115381

    A Few Experiments with 1cP-LSD IΒ’ve came to report a few experiences I have had with 1cP-LSD, a rather new lysergamide, over the past year or so. In that time period, I have Β“researchedΒ” this chemical 6 times with different people.

    Pappus · 100 ug oral
    Horrible Muscle Tension on Comedown neutral exp #113963

    So this actually happened to my gf. We were going on a psychedelic night at this club. She took quarter of one 1cp tab and I took aprox quarter of lsd gel (supposedly 400 ug, but was probably weaker).

    Filo · 25 ug oral
    Anxiety Conquered cautionary exp #119323

    Dosage: 150ΞΌg blotter, 2x75ΞΌg blotters 3 hours later. 300ΞΌg total. Intent: Lower my overall anxiety. Setting: Home alone during calm summer evening. I was in dark place during this time, so I set my mind to doing something with my anxiety, as I regularly experienced panic attacks and felt generally anxious.

    ModraVeverka · 150 ug sublingual / 75 ug sublingual / 75 ug sublingual
    For Depression cautionary exp #114243

    1cP-LSD for Depression (PLEASE NOTE: I was tapering off benzodiazepines with my doctor extremely slowly at the time of the experience. I was not on any type of antidepressant at the time, or one month+ prior to use.

    Misha · 100 ug buccal / smoked

    Bluelight Reference Guide Bluelight

    Lysergamides The Small & Handy 1cP-LSD Thread

    Starting a thread on this substance (1-cyclopropionyl-LSD), as it is available. It should be quite similar to 1p-LSD, and 1b-LSD. Anyone who has tried it, please hare your experiences here.

    Read full thread on Bluelight β†’

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