I want to preface this report with a statement- In a country where drugs are illegal and enforcement of drug laws is largely predicated on race, doing drugs is NOT apolitical.
1cP-LSD
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 19 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 5 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 19 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Aliases: 1cp, Curie, 1-cpa-lsd, 1-cyclopropanoyl-lsd, 1cplsd
Summary
1cP-LSD (1-cyclopropionyl-lysergic acid diethylamide) is an N-1 acylated prodrug that rapidly hydrolyzes to LSD in human serum, producing essentially identical pharmacology to LSD-25. Potency is approximately equivalent to LSD by weight, with most users reporting indistinguishable effects at standard doses. Use reagent testing (Ehrlich or Hofmann) on all batches to ensure authenticity and rule out NBOMe compounds or DOx substances.
Perspectives
“1cP-LSD now stands as one of my favorite lysergamides, second only to LSD itself. Most notable about this compound was that it was extremely visual relative to other lysergamides while remaining very lucid and coherent. There was little body load or overwhelming stimulation.”
“Despite the limited dose this was a good experience. I felt that it was slightly stronger than 1P, with subtle but noticeable differences throughout, and there did seem to be more clarity in parts; perhaps greater control.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 25-75Β΅g | 75-150Β΅g | 150-300Β΅g | 300Β΅g+ |
| Sublingual | 25-75Β΅g | 75-150Β΅g | 150-300Β΅g | 300Β΅g+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 19-60 min | 0.75-2 hrs | 3-5 hrs | 3-5 hrs | 8-10 hrs |
| Sublingual | 19-60 min | 0.75-2 hrs | 3-5 hrs | 3-5 hrs | 8-10 hrs |
Effect Profile
11 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
9.2
Intense+
9/10
Strong visuals, headspace, and auditory effects with moderate body load
Visual Intensity
×3
10
color enhancement
drifting
tracers
synaesthesia
pattern recognition enhancement
scenery slicing
+4 more
Headspace Depth
×3
10
conceptual thinking
introspection enhancement
personal meaning enhancement
recursion
emotion enhancement
personal bias suppression
+1 more
Auditory Effects
×1
10
auditory enhancement
music enhancement
auditory distortion
auditory hallucination
synaesthesia
Body Load / Somatic Effects
×1
6
nausea
vasoconstriction
increased heart rate
Add missing routes to PsychonautWiki Journal
The PsychonautWiki Journal app already has 1cP-LSD, but its built-in entry only covers Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.
⬇ Download import file
Import this file as custom substances
and you get "1cP-LSD (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Custom Unit doses
- Sublingualcommon ~ 112.5 Β΅g
Dose & duration (reference)
1cP-LSD: routes the PsychonautWiki Journal app is missing Source: SubstanceSearch (substancesearch.com) Sublingual dose (Β΅g): threshold 10-20 Β· light 25-75 Β· common 75-150 Β· strong 150-300 Β· heavy 300+ Sublingual duration: onset 0.32-1h Β· come-up 0.75-2h Β· peak 3-5h Β· offset 3-5h Β· total 8-10h Β· after-effects 6-24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Custom Units carry a single dose per route, so the full ranges live in the reference above. A route's suggested dose is the midpoint of its common range. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops rapidly after a single use
Reset
7β14 days for baseline
Tolerance Decay
Full tolerance
1d
Half tolerance
7d
Baseline
~14d
Acute tolerance: develops within a single session β the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Empirical user reports suggest marked tolerance next day with partial recovery over 7β14 days; values are indicative and individualized. Redosing same day extends duration more than intensity.
Cross-Tolerances
Effects
Aggregated from 11 Erowid experience reports
Positive Effects 8
Color Enhancement
72.7%
70%
Music Enhancement
72.7%
70%
Stimulation
63.6%
70%
Euphoria
54.5%
70%
Tactile Enhancement
45.5%
70%
Body High
45.5%
70%
Empathy
36.4%
70%
Introspection
27.3%
70%
Adverse Effects 7
Anxiety
63.6%
70%
Nausea
54.5%
70%
Muscle Tension
36.4%
70%
Jaw Clenching
27.3%
70%
Confusion
27.3%
70%
Pupil Dilation
27.3%
70%
Thought Loops
27.3%
70%
Combinations
Cross-Check 1cP-LSD with another substanceTrip Reports
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 8 reports 2 positive 4 neutral 2 cautionary visit
Boxing the Experience After the small 25ug experiment with this substance in which I made sure that the effects were felt and that they were safe I went on and had a standard trip, some 2 weeks after the LSA one, in order to allow the tolerance to reset.
At 5:00 pm yesterday, I dropped 300ΞΌg of the new "Curie" analogue, 1cP-LSD. I didn't know what to expect, whether it would be similar to 1p-LSD. The comeup was gradual, taking about 1.5hrs, and I experienced no bodyload at all, no nausea or weirdness.
Just recently decided to leave my old job after about 5 yrs and decided to celebrate by dropping a few tabs. I have done LSD prior and felt I was fairly well acquainted with the effects. Ate an early dinner then lounged around for a bit waiting till I was ready to dose.
A Few Experiments with 1cP-LSD IΒve came to report a few experiences I have had with 1cP-LSD, a rather new lysergamide, over the past year or so. In that time period, I have ΒresearchedΒ this chemical 6 times with different people.
So this actually happened to my gf. We were going on a psychedelic night at this club. She took quarter of one 1cp tab and I took aprox quarter of lsd gel (supposedly 400 ug, but was probably weaker).
Dosage: 150ΞΌg blotter, 2x75ΞΌg blotters 3 hours later. 300ΞΌg total. Intent: Lower my overall anxiety. Setting: Home alone during calm summer evening. I was in dark place during this time, so I set my mind to doing something with my anxiety, as I regularly experienced panic attacks and felt generally anxious.
1cP-LSD for Depression (PLEASE NOTE: I was tapering off benzodiazepines with my doctor extremely slowly at the time of the experience. I was not on any type of antidepressant at the time, or one month+ prior to use.
Bluelight Reference Guide
Lysergamides The Small & Handy 1cP-LSD Thread
Starting a thread on this substance (1-cyclopropionyl-LSD), as it is available. It should be quite similar to 1p-LSD, and 1b-LSD. Anyone who has tried it, please hare your experiences here.
Read full thread on Bluelight β
1cP-LSD's nerd page
Pharmacology, chemical data, effect profiles, and more
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