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    2-Aminoindane molecular structure

    2-Aminoindane Stats & Data

    PubChem
    MW133.19
    FormulaC9H11N
    LogP1.7
    IUPAC2,3-dihydro-1H-inden-2-amine
    InChIKeyLMHHFZAXSANGGM-UHFFFAOYSA-N
    Psychoactive Class Stimulant

    Interaction Warnings

    stimulants

    2-AI can be potentially dangerous in combination with other stimulants as it can increase one's heart rate and blood pressure to dangerous levels.

    mdma

    The neurotoxic effects of MDMA may be increased when combined with amphetamine and other stimulants.

    cocaine

    This combination may increase strain on the heart.

    Pharmacology

    DrugBank

    History & Culture

    2-Aminoindane emerged on the research chemical market around 2003, becoming available primarily through online vendors as a designer drug. As an amphetamine analogue with stimulant properties, it attracted interest within the research chemical community despite very limited documentation of its effects or safety profile. The substance has remained relatively obscure compared to other research chemicals, with sparse information available regarding its recreational use patterns or prevalence. Its availability has been predominantly as an off-white powder marketed through grey market sources, with oral administration being the primary reported route of use.

    Subjective Effect Notes

    physical: The physical effects of 2-AI can be broken down into several components which progressively intensify proportional to dosage.

    cognitive: The general head space of 2-AI is described by many as one of mental stimulation, increased focus, and euphoria. It contains a large number of typical stimulant cognitive effects. Although negative side effects are usually mild at low to moderate doses, they become increasingly likely to manifest themselves with higher amounts or extended usage. This particularly holds true during the offset of the experience.

    Toxicity

    PsychonautWiki

    The toxicity and long-term health effects of recreational 2-AI use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because 2-AI has very little history of human usage. Anecdotal evidence from people who have tried 2-AI within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed). It is strongly recommended that one use harm reduction practices when using this drug.

    Effect Profile

    Curated
    Stimulant 5.4

    Strong focus and anxiety/jitters with mild stimulation and euphoria

    Stimulation / Energy×3
    5
    Euphoria / Mood Lift×2
    5
    Focus / Productivity×2
    8
    Anxiety / Jitters×1
    8

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Legal Status

    Country Status Notes
    Austria Illegal (NPSG) Prohibited under the Neue-Psychoaktive-Substanzen-Gesetz (New Psychoactive Substances Act). Possession, production, and sale are all illegal.
    China Controlled Classified as a controlled substance since October 2015.
    Finland Controlled Scheduled under the government decree on psychoactive substances banned from the consumer market.
    Germany Controlled (NpSG) Controlled under the Neue-psychoaktive-Stoffe-Gesetz (New Psychoactive Substances Act) since November 26, 2016. Production and import with intent to distribute, administration to others, and trading are punishable offenses. Possession is prohibited but not subject to criminal penalties.
    Russia Controlled 2-aminoindane and certain derivatives have been classified as controlled substances since June 4, 2012.
    Sweden Proposed for scheduling Sweden's public health agency recommended classifying 2-AI as a hazardous substance on June 24, 2019. Current legal status may have changed following this recommendation.
    Switzerland Controlled (Verzeichnis E) Specifically named as a controlled substance under Verzeichnis E of Swiss narcotics legislation.
    United Kingdom Illegal (Psychoactive Substances Act) Prohibited under the Psychoactive Substances Act 2016, which came into effect on May 26, 2016. Production, supply, and importation are criminal offenses.
    United States Unscheduled Not specifically controlled at the federal level, meaning possession is generally legal. However, 2-AI may be considered an analogue of amphetamine, in which case purchase, sale, or possession with intent for human consumption could potentially be prosecuted under the Federal Analog Act.
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