2-Aminoindane Stats & Data
LMHHFZAXSANGGM-UHFFFAOYSA-NInteraction Warnings
2-AI can be potentially dangerous in combination with other stimulants as it can increase one's heart rate and blood pressure to dangerous levels.
The neurotoxic effects of MDMA may be increased when combined with amphetamine and other stimulants.
This combination may increase strain on the heart.
History & Culture
2-Aminoindane emerged on the research chemical market around 2003, becoming available primarily through online vendors as a designer drug. As an amphetamine analogue with stimulant properties, it attracted interest within the research chemical community despite very limited documentation of its effects or safety profile. The substance has remained relatively obscure compared to other research chemicals, with sparse information available regarding its recreational use patterns or prevalence. Its availability has been predominantly as an off-white powder marketed through grey market sources, with oral administration being the primary reported route of use.
Subjective Effects
Physical
The physical effects of 2-AI can be broken down into several components which progressively intensify proportional to dosage.
- Stimulation: In terms of its effects on the physical energy levels of the user, 2-AI is usually considered to be energetic and stimulating in a fashion that is similar to that of amphetamine but stronger than that of modafinil or caffeine. It is similar yet distinct from the stimulation experienced on MDMA, encouraging physical activities such as dancing, socializing, running, or cleaning. The particular style of stimulation which 2-AI presents can be described as forced. This means that at higher doses, it becomes difficult or impossible to keep still as jaw clenching, involuntarily bodily shakes and vibrations become present, resulting in extreme shaking of the entire body, unsteadiness of the hands, and a general lack of motor control.
- Pain relief: Many anecdotal reports suggest that this compound may suppress pain in a fashion somewhat similar to opioids without the distinct physical euphoria.
- Increased heart rate
- Dehydration
- Appetite suppression
- Nausea
- Temporary erectile dysfunction
- Increased perspiration
Cognitive
The general head space of 2-AI is described by many as one of mental stimulation, increased focus, and euphoria. It contains a large number of typical stimulant cognitive effects. Although negative side effects are usually mild at low to moderate doses, they become increasingly likely to manifest themselves with higher amounts or extended usage. This particularly holds true during the offset of the experience.
- Focus enhancement: This component is most effective at low to moderate doses as anything higher will usually impair concentration.
- Thought acceleration
- Analysis enhancement
- Wakefulness
- Memory enhancement
- Motivation enhancement
- Euphoria
- Compulsive redosing
- Cognitive fatigue
- Anxiety
- Depression
Sensory
- Acuity enhancement
Forked from Subjective Effect Documentation by Josie Kins, September 2015. Via dose.wiki (CC0).
Toxicity
PsychonautWikiThe toxicity and long-term health effects of recreational 2-AI use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because 2-AI has very little history of human usage. Anecdotal evidence from people who have tried 2-AI within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed). It is strongly recommended that one use harm reduction practices when using this drug.
Effect Profile
CuratedStrong focus and anxiety/jitters with mild stimulation and euphoria
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Legal Status
| Country | Status | Notes |
|---|---|---|
| Austria | Illegal (NPSG) | Prohibited under the Neue-Psychoaktive-Substanzen-Gesetz (New Psychoactive Substances Act). Possession, production, and sale are all illegal. |
| China | Controlled | Classified as a controlled substance since October 2015. |
| Finland | Controlled | Scheduled under the government decree on psychoactive substances banned from the consumer market. |
| Germany | Controlled (NpSG) | Controlled under the Neue-psychoaktive-Stoffe-Gesetz (New Psychoactive Substances Act) since November 26, 2016. Production and import with intent to distribute, administration to others, and trading are punishable offenses. Possession is prohibited but not subject to criminal penalties. |
| Russia | Controlled | 2-aminoindane and certain derivatives have been classified as controlled substances since June 4, 2012. |
| Sweden | Proposed for scheduling | Sweden's public health agency recommended classifying 2-AI as a hazardous substance on June 24, 2019. Current legal status may have changed following this recommendation. |
| Switzerland | Controlled (Verzeichnis E) | Specifically named as a controlled substance under Verzeichnis E of Swiss narcotics legislation. |
| United Kingdom | Illegal (Psychoactive Substances Act) | Prohibited under the Psychoactive Substances Act 2016, which came into effect on May 26, 2016. Production, supply, and importation are criminal offenses. |
| United States | Unscheduled | Not specifically controlled at the federal level, meaning possession is generally legal. However, 2-AI may be considered an analogue of amphetamine, in which case purchase, sale, or possession with intent for human consumption could potentially be prosecuted under the Federal Analog Act. |