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    2-FEA molecular structure

    2-FEA Stats & Data

    O-fluoroethamphetamine 2-fluoroethylamphetamine Ortho-fluoroethamphetamine
    NPS DataHub
    MW181.25
    FormulaC11H16FN
    CAS3823-29-8
    IUPACN-ethyl-1-(2-fluorophenyl)propan-2-amine
    SMILESCCNC(C)Cc1ccccc1F
    InChIKeyNIWYLNFSJJLYHU-UHFFFAOYSA-N
    Phenethylamines; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Amphetamine
    Psychoactive Class Psychedelic / Stimulant
    Half-Life Unknown in humans. User reports suggest an effect window of roughly 4–8 hours with residual stimulation beyond this; do not assume duration equals safety.

    Receptor Profile

    Receptor Actions

    Inhibitors
    Serotonin-dopamine-norepinephrine reuptake inhibitor (SNDRI)
    Other
    Serotonin-dopamine-norepinephrine releasing agent (SNDRA)

    History & Culture

    2-FEA emerged as a novel psychoactive substance distributed through online research chemical vendors. Limited formal documentation exists regarding its precise origins, initial synthesis, or the circumstances of its introduction to the recreational drug market. As a fluorinated amphetamine derivative, 2-FEA follows a broader pattern of substituted amphetamine analogues appearing on the research chemical market, though specific details about when it first became commercially available remain poorly documented in the available literature.

    Effect Profile

    Curated
    Psychedelic 1.8

    Strong body load with low visuals and headspace

    Visual Intensity×3
    3
    Headspace Depth×3
    1
    Auditory Effects×1
    0
    Body Load / Somatic Effects×1
    8
    Empathogen 3.4

    Moderate stimulation and euphoria with mild sensory enhancement

    Empathy / Social Openness×3
    0
    Euphoria / Mood Elevation×2
    6
    Stimulation×1
    7
    Sensory Enhancement×1
    5
    Stimulant 6.6

    Strong anxiety/jitters and focus with moderate stimulation and euphoria

    Stimulation / Energy×3
    7
    Euphoria / Mood Lift×2
    7
    Focus / Productivity×2
    9
    Anxiety / Jitters×1
    10

    Tolerance & Pharmacokinetics

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    Half-Life
    Unknown in humans. User reports suggest an effect window of roughly 4–8 hours with residual stimulation beyond this; do not assume duration equals safety.
    Addiction Potential
    Moderate (anecdotal). As a stimulant, 2-FEA can produce compulsive redosing and psychological dependence. Pre-measuring doses and avoiding large supplies within reach can reduce this risk.

    Legal Status

    Country Status Notes
    Canada Schedule I (analogue) Considered a Schedule I controlled substance as an analogue of amphetamine under Canadian drug scheduling laws.
    France Not scheduled As of December 2024, 2-FEA is not explicitly scheduled under French drug control legislation. Possession is technically legal, though the substance exists in a regulatory gray area.
    Germany NpSG controlled Controlled under the Neue-psychoaktive-Stoffe-Gesetz (New Psychoactive Substances Act) since November 26, 2016. Production and import with intent to market, administration to others, and trading are punishable offenses. Possession is prohibited but not subject to criminal penalties.
    Netherlands Legal (pending review) Currently unscheduled and legal to possess. However, 2-FEA falls within a substance group that may be prohibited under recently passed legislation targeting new psychoactive substances.
    New Zealand Schedule 3 Classified as a Schedule 3 controlled substance due to its structural relationship to amphetamine under New Zealand's analogue provisions.
    Switzerland Controlled (Verzeichnis E) Regulated as a controlled substance under Verzeichnis E point 130 as a defined derivative of α-methylphenethylamine. Exemptions exist for legitimate scientific or industrial applications.
    United Kingdom Class A Controlled as a Class A substance under the amphetamine analogue clause of the Misuse of Drugs Act 1971. Class A classification carries the most severe penalties under UK drug law.
    United States Unscheduled Not a federally controlled substance as of 2011. However, prosecution may be possible under the Federal Analogue Act when sold or possessed with intent for human consumption, as it is structurally related to scheduled amphetamines.

    Harm Reduction

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    • Identity and purity: Mislabeling and substitutions are common in the NPS market. Where possible, use an official drug checking service (GC‑MS/FT‑IR). If no lab testing is available, test a very small dose first and wait; for oral use, wait at least 2 hours before considering more. Use your own snorting equipment to reduce infection risk.

    • Dosing discipline: Start low and go slow. Pre‑measure doses with a milligram scale. For faster routes (insufflated/rectal), pre‑plan a maximum total session amount to reduce chasing effects. TripSit provides a volumetric dosing tool and combination guidance.

    • Heat and hydration: Stimulants increase body temperature and fluid loss. Take regular cool‑down breaks if active/hot, sip fluids slowly, and avoid overhydration. A practical rule-of-thumb from clubbing harm‑reduction: about one pint (~500 mL) per hour when exerting, with breaks; do not force excessive water (risk of hyponatremia).

    • Cardiovascular risk: Like other synthetic stimulants, 2-FEA may elevate heart rate and blood pressure. Avoid combining with other stimulants, and people with cardiovascular disease should be especially cautious or avoid use.

    • Redosing/compulsion: Stimulants can promote compulsive redosing. To reduce risk, plan session limits, store the remainder out of reach/sight, and consider having a trusted person hold the supply.

    • Nasal health: If insufflating, use your own straw/tube, avoid frequent large lines, and gently rinse with saline after sessions to reduce irritation.

    • Sleep and comedown: Expect insomnia and a low mood the following day. Prioritize rest, nutrition, and rehydration. Avoid using alcohol, benzodiazepines, or opioids to force sleep due to interaction risks.

    • Evidence limits: There are no controlled human pharmacokinetic studies for 2-FEA. All typical dose/duration ranges here are from user reports; individual responses vary widely. Prefer lab confirmation and conservative titration. (General NPS preparedness guidance.)

    References

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