2-MPPP
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: N-piperidinecathinone
Summary
2-MPPP is a little-studied research chemical first reported in 2014-2015. No formal toxicology or pharmacokinetic data exist. Users describe short-lived, 'clean' mental stimulation with mild euphoria, minimal peripheral push, and a relatively soft comedown.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 25-50mg | 50-100mg | 100-150mg | 150mg+ |
| Insufflated | 15-30mg | 30-60mg | 60-110mg | 110mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 20-30 min | 30-90 min | 1-2 hrs | 2-4 hrs |
| Insufflated | 3-7 min | 30-90 min | 1-2 hrs | 2-4 hrs |
| Rectal | 2-5 min | 30-90 min | 1-2 hrs | 2-4 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria with mild anxiety/jitters, low focus
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 2-MPPP there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
2-MPPP Source: SubstanceSearch (substancesearch.com) Oral dose (mg): light 25-50 · common 50-100 · strong 100-150 · heavy 150+ Insufflated dose (mg): light 15-30 · common 30-60 · strong 60-110 · heavy 110+ Rectal dose (mg): threshold 10 Oral duration: onset 20-30m · peak 0.5-1.5h · offset 1-2h · total 2-4h · after-effects 1-12h Insufflated duration: onset 3-7m · peak 0.5-1.5h · offset 1-2h · total 2-4h · after-effects 1-12h Rectal duration: onset 2-5m · peak 0.5-1.5h · offset 1-2h · total 2-4h · after-effects 1-12h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 75 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Anecdotal reports suggest tolerance builds rapidly with consecutive-day use (2–3 days) and partially subsides over about a week, with near‑baseline after 10–14 days. Cross‑tolerance likely with other monoaminergic stimulants (cathinones/amphetamines). Data are low quality and user‑reported.
Effects
- Mental stimulation/alertness
- Increased energy/alertness
- Bruxism and jaw tension
- Mild vasoconstriction
- Sweating
- Tachycardia and elevated blood pressure
- Insomnia
- Weight loss
- Bruxism
- Decreased need for sleep
- Decreased appetite
- Disturbed sleep patterns
- Itchiness
- Euphoria
- Mood elevation
- Increased sociability and talkativeness
- Motivation enhancement
- Increased sociability
- Mood lift
- Anxiety or irritability on comedown
- Aggressiveness
- Excessive talking
- Moodiness
- Music appreciation enhancement
- Color enhancement
- Increased music appreciation
- Brightened colour
- Appetite suppression
- Light sensitivity
- Disinhibition
- Increased sexuality
- Visual and auditory hallucinations
- Dulled perception
Combinations
Cross-Check 2-MPPP with another substanceHelpful Links
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