2-PTA
Aliases: Cumylamine, 4-methyl-2-pa, 2-(p-tolyl)acetamide
Categories
Summary
Human data remain extremely limited (โค50 self-reports). Acute adverse effects recorded include marked tachycardia (>130 bpm), vasoconstriction, jaw tension, blurred vision and short-lived chest discomfort at โฅ60 mg. Because the amide replaces the ฮฑ-methyl, potency is roughly one-quarter of amphetamine but pressor effects are still pronounced. Neurotoxicity has not been assessed; amphetamine-like oxidative stress is plausible at high temperatures or long binges - keep body temperature <38ยฐC and supplement antioxidants (e.g., 500 mg vitamin C). Always perform an allergy test โค1 mg.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-20mg | 20-40mg | 40-80mg | 80+mg+ |
| Sublingual | 10-20mg | 20-40mg | 40-80mg | 80+mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|
| Oral | 10-25 min | 45-90 min | 30-60 min | 1-6 hrs | 60-0 min |
| Insufflated | 2-8 min | 45-90 min | 30-60 min | 1-6 hrs | 60-0 min |
| Sublingual | 600-0 min | 45-90 min | 30-60 min | 1-6 hrs | 60-0 min |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3โ7 days for acute tolerance; longer for full reset
Effects
Positive
- Stimulation
Negative
- Tachycardia
- Increased blood pressure
- Vasoconstriction
- Teeth grinding
- Temperature regulation suppression
- Insomnia
- Increased heart rate
- Increased perspiration
- Difficulty urinating
Positive
- Euphoria
- Focus enhancement
- Increased sociability
- Motivation enhancement
- Enhanced focus
- Cognitive enhancement
Negative
- Anxiety
- Cognitive fatigue
- Irritability
- Time distortion
Positive
- Increased libido
- Color enhancement
- Increased music appreciation
- Tactile enhancement
Negative
- Appetite suppression
- Light sensitivity
- Dehydration
- Disinhibition
- Dulled perception
- Drifting