25C-NB3OMe
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- descriptive-only dose data
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 2 corroborating sources
- descriptive-only dose data
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: 30c-nbome, 2c-c-nb3ome, Nb3ome-2c-c, 25c-nb345ome
Summary
C30-NBOMe (also known as 30C-NBOMe or 25C-NB345OMe) is structurally distinct from typical NBOMes due to its 3,4,5-trimethoxybenzyl group (mescaline-like pattern) rather than the standard 2-methoxybenzyl group. Despite being theoretically related to active NBOMe compounds, extensive anecdotal evidence from 2013-2016 indicates this substance produces minimal to no psychoactive effects at doses ranging from micrograms to hundreds of milligrams across multiple routes of administration. Only one isolated positive report exists amid numerous reports of complete inactivity.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | - | - | - | No reliable effects at 300+ mg |
| Sublingual | - | - | - | No effects observed at 50+ mg |
| Intravenous | - | - | - | No effects reported at 20 mg |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Buccal | 20-60 min | 30-60 min | 1.5-3.5 hrs | 2-4 hrs | 4.33-9.5 hrs |
| Insufflated | 5-20 min | 15-30 min | 1.5-3.5 hrs | 2-4 hrs | 3.83-8.33 hrs |
| Oral | 30-90 min | 45-90 min | 1.5-3.5 hrs | 2-4 hrs | 4.75-10.5 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong visuals, body load, and auditory effects with mild headspace
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25C-NB3OMe Source: SubstanceSearch (substancesearch.com) Buccal dose: threshold 200-400 Insufflated dose: threshold 100-300 Oral dose: threshold No effects reported at standard doses · heavy No reliable effects at 300+ mg Sublingual dose: threshold Unknown - no reliable effects reported · heavy No effects observed at 50+ mg Intravenous dose: threshold — · heavy No effects reported at 20 mg Buccal duration: onset 0.33-1h · come-up 0.5-1h · peak 1.5-3.5h · offset 2-4h · total 4.33-9.5h · after-effects 2-6h Insufflated duration: onset 5-20m · come-up 15-30m · peak 1.5-3.5h · offset 2-4h · total 3.83-8.33h · after-effects 2-6h Oral duration: onset 0.5-1.5h · come-up 0.75-1.5h · peak 1.5-3.5h · offset 2-4h · total 4.75-10.5h · after-effects 2-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Patterns extrapolated from classical psychedelic tolerance; individual variability is high. Repeated high‑frequency use may cause prolonged after‑effects or HPPD‑like symptoms as reported anecdotally.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Peripheral vasoconstriction
- Body load
- Teeth grinding
- Nausea
- Increased heart rate
- Pupil dilation
- Dilated pupils
- Sedation
- Euphoria
- Empathy
- After-glow
- Conceptual thinking
- Anxiety
- Confusion
- Memory suppression
- Motor control loss
- Time distortion
- No consistent psychoactive effects reported
- Visual geometry
- Color enhancement
- Auditory enhancement
- Tactile enhancement
- Tracers
- Increased music appreciation
- Enhanced tactile sensation
- Visual distortions
- Drifting
- Auditory distortion
Combinations
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