I am a cosmonaut of the fifth degree. I have experience with 2c-b, 2c-p, dmt, lsd, mdma, methylone, 25b, 25c, 25d, 25e, 25i, 25n, 25p, 5-meo-dmt. I also smoke a fair amount of medical cannabis. I have came in possession of 30 mg 2C-P-NBOMe.
25P-NBOMe
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 19 combo interactions documented
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 19 combo interactions documented
- classified Tentative
- classified Research-chemical
Aliases: Nbome-2c-p
Summary
Extremely potent compound active in the low hundreds of micrograms range. Small measurement errors can create dangerous multi-fold overdoses. Reports of intense vasoconstriction, tachycardia, hypertension, agitation, and seizures at high doses, with multiple documented fatalities in the NBOMe series.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Sublingual | 250-450ug | 450-700ug | 700-1500ug | 1500µg+ |
| Oral | 250-450ug | 450-700ug | 700-1500ug | 1500ug+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Sublingual | 10-30 min | 30-60 min | 2-5 hrs | 4-8 hrs | 7-14 hrs |
| Insufflated | 2-10 min | 15-30 min | 2-5 hrs | 4-8 hrs | 7-14 hrs |
| Vaporized | 2-5 min | 10-20 min | 2-5 hrs | 4-8 hrs | 7-14 hrs |
| Oral | 25-40 min | - | 7-14 hrs | - | 7-14 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
3.8
Moderate
4/10
Moderate body load with mild visuals and headspace
Visual Intensity
×3
5
color enhancement
color shifting
brightened colour
Headspace Depth
×3
4
thought connectivity
time distortion
confusion
Auditory Effects
×1
0
Body Load / Somatic Effects
×1
7
vasoconstriction
nausea
muscle tension
Based on reports from:
Tolerance
Build-up
develops rapidly after a single use (serotonergic psychedelic)
Reset
7–14 days for baseline
Tolerance Decay
Full tolerance
1h
Half tolerance
10d
Baseline
~14d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Positive
- Stimulation
- Mental/physical stimulation
Negative
- Vasoconstriction
- Nausea
- Pupil dilation
- Restlessness
- Sweating/chills
- Muscle tension
- Insomnia
- Body temperature fluctuations
- Mouth numbing
- Decreased appetite
Positive
- Euphoria
- Thought connectivity
- Empathy
- Insight
Negative
- Mania
- Anxiety
- Paranoia
- Afterglow or fatigue
- Confusion
- Thought acceleration
- Time distortion
- Change in perception
- Ego softening
Positive
- Color enhancement
- Color shifting
- Tactile enhancement
- Brightened colour
- Enhanced tactile sensation
Negative
- Tactile suppression
- Appetite suppression
- Visual patterning
- Spatial depth distortion
- Closed/Open eye visuals
Combinations
Cross-Check 25P-NBOMe with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 1 report 1 neutral visit
25P-NBOMe's nerd page
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Helpful Links
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