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    Disclaimer
    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    2C-C Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 6 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 18 combo interactions documented
    • PubChem toxicity data
    • classified Research-chemical

    Aliases: 2cc

    Summary PsychonautWiki

    4-Chloro-2,5-dimethoxyphenethylamine (commonly known as 2C-C) is a lesser-known psychedelic substance of the phenethylamine class that produces psychedelic effects when administered. It is a member of the 2C-x family of psychedelic phenethylamines, all of which were derived from the systematic modification of the mescaline molecule.

    Perspectives

    “Intranasal 2C-C features greater potency, faster comeup, shorter duration. Characterized by latent energy with bright pulsing and flashing visuals, architectural and structural and artificial in nature.”

    “This is longer lived than 2C-B, and there is a longer latency in coming on. It took an hour and a half, or even two hours to get there. It had a slight metallic overtone.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 15-30mg 30-50mg 50-90mg 90mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 19-45 min 45-90 min 2-3 hrs 1-3 hrs 4-12 hrs 4-7 hrs
    Insufflated 4-19 min 30-60 min 2-3 hrs 1-3 hrs 2-6 hrs 4-8 hrs

    Effect Profile

    135 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 99 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.8
    Intense+ 9/10

    Strong visuals, headspace, auditory effects, and body load

    Visual Intensity ×3
    10
    external hallucinations internal hallucinations color enhancement autonomous entities drifting tracers +4 more
    Headspace Depth ×3
    10
    conceptual thinking thought connectivity emotion enhancement perspective alterations personal bias suppression time distortion +1 more
    Auditory Effects ×1
    10
    auditory distortion auditory enhancement auditory hallucinations auditory hallucination
    Body Load / Somatic Effects ×1
    10
    nausea temperature regulation suppression muscle tension teeth grinding increased heart rate
    Stimulant 6.9
    Strong+ 7/10

    Strong anxiety/jitters and stimulation with moderate euphoria and focus

    Stimulation / Energy ×3
    9
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    7
    euphoria
    Focus / Productivity ×2
    7
    analysis enhancement thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety restlessness increased heart rate teeth grinding muscle tension

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7โ€“14 days for baseline

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~14d

    General psychedelic tolerance pattern: rapid tolerance after a single session, partial decay in ~3 days, nearโ€‘baseline by ~1โ€“2 weeks for most users. Data are largely anecdotal by extrapolation from 2Cโ€‘B, mescaline, and classโ€‘wide sources.

    Effects Erowid Bluelight

    Aggregated from 99 Erowid and 36 Bluelight experience reports

    Positive Effects 76

    Visual Distortions 65.2% 78%
    Color Enhancement 48.9% 86%
    Euphoria 48.9% 90%
    Stimulation 39.2% 81%
    Music Enhancement 37.8% 87%
    Tactile Enhancement 35.5% 85%
    Empathy 35.5% 84%
    Contentment 33.3% 84%
    Sedation 32.6% 82%
    Introspection 31.8% 83%
    Closed-Eye Visuals 27.4% 88%
    Geometric Imagery 25.0% 88%
    Body High 22.2% 88%
    Patterning 22.2% 89%
    Surface Breathing 22.2% 84%
    Focus Enhancement 20.7% 83%
    Auditory Effects 20.0% 80%
    Awe 19.4% 83%
    Thought Acceleration 19.4% 77%
    Libido Enhancement 19.4% 82%

    Adverse Effects 41

    Anxiety 36.3% 83%
    Body Load 36.1% 70%
    Nausea 32.6% 72%
    Confusion 26.6% 80%
    Headache 14.0% 80%
    Fear 13.9% 85%
    Tension 13.9% 83%
    Sweating 11.1% 88%
    Chills 11.1% 82%
    Motor Impairment 10.4% 75%
    Memory Suppression 8.9% 70%
    Dysphoria 8.3% 80%
    Hot Flashes 8.3% 80%
    Body Temperature Change 8.3% 82%
    Restlessness 8.3% 79%
    Thought Deceleration 8.3% 78%
    Delusion 8.3% 92%
    Jaw Clenching 7.4% 71%
    Increased Heart Rate 7.1% 70%
    Sadness 5.6% 75%

    Combinations TripSit

    Cross-Check 2C-C with another substance

    Trip Reports Effect Index

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
    Quite Pleasant positive exp #25372

    Substance - 2C-C (2,5-dimethyoxy-4-chlorophenethylamine) Experience - First time Setting - my basement Many of my past reports have shown I am favorable to 2C-I. It was the first phenethylamine I ever tried. I fell in love with 2C-I and wanted to see what other experiences the 2C family had to offer.

    Matt Himself · 36 mg oral
    An Exfoliating Mud-bath for the Soul positive exp #34841

    Dose: 2C-C powder was measured at a dose of 50mg and taken orally in a gelatin capsule. Duration: The full-blown experience lasted about 4 hours, with 3 additional hours of after effects.

    Nog · 50 mg oral
    Good Fun Trip positive exp #82208

    Tried for the first time last night. Had 125mg and me and my mate went through the lot doin 15 or 20mg lines, can't remember! Tracers looked fookin amazing, and there was loads of little particles zipping about - shiny stuff like tin foil looked cool and zippy aroundish too :-) .

    Naboo The Enigma · 50 mg insufflated
    Gorgeous and Deeply Satisfying neutral exp #111270

    A Gorgeous and Deeply Satisfying Experience This was my first experience with 2C-C. I had been putting it off for a while even though I had been really wanting to explore it and other phenethylamines more simply because my supply of them is much more limited than of the tryptamines or lysergamides, so I've been wanting...

    Kaleida · 33 mg oral / repeated smoked / 8 carts. inhaled
    First Trials neutral exp #75345

    I wanted to compare the structural activity of the lesser-known phenethylamine 2C-C to that of itย’s closely-related neighbor, 2C-B, a compound that I personally have always enjoyed. I placed an order and when my sample arrived, it appeared more or less identical to 2C-B: a fluffy, finely-textured white powder.

    LucidStudies · 20 mg oral / 30 mg oral
    Beautiful, Rewarding, and Underrated neutral exp #48532

    In this report, I try to provide a very thorough and accurate description of the nature of 2C-C. If you donย’t want to read a detailed description of the effects, then you should just skip to the second to last paragraph ย“Summery of my 2C-C experienceย” for a concise summery of its impression on me.

    Cactushead · 20 mg oral
    Tripping at Settler's Rock cautionary exp #25426

    July 16, 2003 I must begin by saying that my actions during this trip were the stupidest and most irresponsible of anything I have ever done while on a psychedelic. What I did should be an example to all of what not to do when you are tripping for the first on a high dose of an experimental substance.

    Morninggloryseed
    Set and Setting Sensitive Psychosis cautionary exp #52261

    Space and time: New York City, March 2006 A strong dose of 2C-C in a public setting resulted in an overwhelming and paranoid experience. In retrospect, guinea pigging a new drug outside of a careful and private setting was very foolish and the ultimate reason that this trip went awry.

    Trippopotamus · 40 mg oral / 30 mg oral / oral
    Bluelight 8 threads 1 positive 6 neutral 1 cautionary visit
    2c C First Time Quite Pleasant positive

    Substance โ€“ 2C-C (2,5-dimethyoxy-4-chlorophenethylamine) Experience โ€“ First time Setting โ€“ my basement Many of my past reports have shown I am favorable to 2C-I. It was the first phenethylamine I ever tried. I fell in love with 2C-I and wanted to see what other experiences the 2C family had to offer.

    scraped 2026-03-14
    2c C Second Time 36mg neutral

    2-CC, 36mg Some quick background about my experience with hallucinagens - mushrooms, LSD, 4-ACO, 5MEO-DMT, salvia, and most recently 2-CC. Approx. two weeks ago I tried 2-CC for the first time, did 33mg via pill and thoroughly enjoyed it. I dosed and then went into the woods for a day of hiking and relaxing.

    scraped 2026-03-14
    2c C Second Time Good Vibrations neutral

    Forgive the cheesy title 'good vibrations'. Not an original phrase to use in relation to psychedelia, but it seemed an appropriate one, given the focus of the peak of the experience.

    scraped 2026-03-14
    2c C 33 Mg First Time A Gorgeous And Deeply Satisfying Experience neutral

    This was my first experience with 2C-C. I had been putting it off for a while even though I had been really wanting to explore it and other phenethylamines more simply because my supply of them is much more limited than of the tryptamines or lysergamides, so I've been wanting to make sure I wait for the perfect times t...

    scraped 2026-03-14
    2c C First Time My What A Slow And Shapely Triangle But Oh My Legs neutral

    My first trip report here, this, as well as being my first time with 2C-C. I'm sure I've given too little or too much detail on various aspects. Please do ask questions, if anything needs fleshing out. Dose, substance, route I took 36 mg (+/- 1 mg) of 2C-C, orally.

    scraped 2026-03-14
    2c C First Time Tripping At Settlers Rock neutral

    July 16, 2003 Fifty-milligrams of 2,5-dimethoxy-4-chlorophenethylamine hydrochloride I must begin by saying that my actions during this trip were the stupidest and most irresponsible of anything I have ever done while on a psychedelic.

    scraped 2026-03-14
    2c C Approx 150mg 1st Trip cautionary

    Ok if you want to skip the boring preface part just got down a bit and start reading from The Trip. Preface: Ok so 150mg sounds a bit extreme and possibly foolish. It's possible I may have built up some tolerance from taking 2C-C the previous night. So I do not know if 150mg would be too much or okay for someone else.

    scraped 2026-03-14

    Bluelight Reference Guide Bluelight

    โ˜› Official โ˜š The Big & Dandy 2C-C Thread - V2: Chlory hallelujah

    External Information Links: Erowid 2C-C Vault (experience reports) PIHKAL Entry on 2C-C Wikipedia entry Link to previous thread Continue discussion, you rapscallions.

    Read full thread on Bluelight โ†’

    PiHKAL / TiHKAL Shulgin

    PiHKAL #22: 2C-C

    “This is longer lived than 2C-B, and there is a longer latency in coming on. It took an hour and a half, or even two hours to get there. It had a slight metallic overtone.”

    โ€” Alexander Shulgin, PiHKAL (with 20 mg)

    Helpful Links