2C-EF - Substance Search

Summary dose.wiki

Extremely limited human data exists for 2C-EF. Start with low doses and verify substance identity via reagent testing or spectroscopy. Avoid combining with serotonergic agents or lithium.

Dose Information dose.wiki Drugs.Wiki

Dose basis. Ranges are drawn from early Bluelight collation (fastandbulbous/B9) and 2024–2025 user reports; variability has been noted across batches and pressed tablets. Use a milligram scale and preferably volumetric dosing; avoid eyeballing. Start with an allergy test (≤1–2 mg) and titrate slowly in 2–3 mg steps on separate days. Evidence base: primarily user reports and forum synthesis. (Dose figures and this note are from Drugs.Wiki.)

ROA	Light	Common	Strong	Heavy
Oral	4-8mg	8-12mg	12-16mg	16mg+

Light Common Strong Heavy

Onset, Duration & After-effects dose.wiki Drugs.Wiki

ROA	Onset	Comeup	Peak	Offset	After Effects	Total
Oral	15-60 min	30-60 min	2-4 hrs	6-8 hrs	1-2 hrs	8.75-14 hrs

Effect Profile

8 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Psychedelic 5.8

Strong 6/10

Strong visuals with moderate body load, mild headspace

Visual Intensity ×3

10

visual geometry color enhancement drifting tracers pattern recognition enhancement color shifting +1 more

Headspace Depth ×3

4

introspection time distortion confusion

Auditory Effects ×1

0

⚠ Body Load / Somatic Effects ×1

6

nausea muscle tension increased heart rate

Based on reports from:

Erowid Experience Reports

Add to PsychonautWiki Journal

The PsychonautWiki Journal logging app doesn't include every substance. To track 2C-EF there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

⬇ Download import file Import this file as custom substances and you get "2C-EF (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.

Name

2C-EF

Unit

mg

Description

2C-EF
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): threshold 2-4 · light 4-8 · common 8-12 · strong 12-16 · heavy 16+

Oral duration: onset 0.25-1h · come-up 0.5-1h · peak 2-4h · offset 6-8h · total 8.75-14h · after-effects 1-2h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 10 mg (Oral).

The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

Tolerance

Build-up develops rapidly after a single use

Reset 7–14 days for baseline

Tolerance Decay

Half tolerance 7d Baseline ~14d

Pattern inferred from general 5‑HT2A psychedelic tolerance: acute near‑complete tolerance same day; partial recovery over ~3–7 days; baseline by ~1–2 weeks. Data quality: anecdotal/analogy.

Cross-Tolerances

other 2C phenethylamines

50%

tryptamine psychedelics

30%

Effects Erowid

Aggregated from 8 Erowid experience reports

Positive Effects 7

Euphoria 87.5% 70%

Color Enhancement 62.5% 70%

Empathy 62.5% 70%

Music Enhancement 62.5% 70%

Tactile Enhancement 50.0% 70%

Introspection 50.0% 70%

Stimulation 37.5% 70%

Adverse Effects 5

Muscle Tension 50.0% 70%

Confusion 37.5% 70%

Anxiety 37.5% 70%

Jaw Clenching 37.5% 70%

Nausea 37.5% 70%

Combinations

Cross-Check 2C-EF with another substance

Community Trip Reports

Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

Erowid 8 reports 6 positive 1 neutral 1 cautionary visit

Smooth as Silk and Warm Like Sunshine positive exp #113370

[Erowid Note: Two of two samples of material sold as 2C-EF and analyzed by Erowid's DrugsData service were actually other 2C- compounds.] 2C-EF - First Time - 7-4-2019 - "Smooth As Silk and Warm Like Sunshine" By Xorkoth I've been interested in 2C-EF ever since our dear fastandbulbous synthesized it and a few reports g...

A Gentle and Pleasant Ride positive exp #113665

[Erowid Note: Two of two samples of material sold as 2C-EF and analyzed by Erowid's DrugsData service were actually other 2C- compounds.] P 155lb male experienced with psychedelics (me) 15mg 2C-EF R 155lb male psychedelic naïve 15mg 2C-EF A 100lb female psychedelic naïve 15mg 2C-EF B 200lb male ps...

High Dose, Disappointment positive exp #119413

I dont usually write reviews, but since this compound has very few experience reports available, this might be useful as a guide for others. First, my background: 35 years old, male, 90 kg, I exercise regularly. Keep that in mind, because this compound feels a bit heavy on the cardiovascular side.

It's a Wonderful Night positive exp #91746

[Erowid Note: Two of two samples of material sold as 2C-EF and analyzed by Erowid's DrugsData service were actually other 2C- compounds.] A footnote in Pihkal reckons that 2C EF would be a winner if anyone ever made it & the dosage would likely be between 12 and 24 mgs.

Fun and Trippy, but Not for an Indoor Rave neutral exp #118500

Erowid Note: Two of two samples of material sold as 2C-EF and analyzed by Erowid's DrugsData service were actually other 2C- compounds.] So yesterday me and my gf went to a club and wanted to try those 2c-ef 10mg pellets from a famous clearnet vendor.

An Obscure and Beautiful Phenethylamine positive exp #112521

[Erowid Note: Two of two samples of material sold as 2C-EF and analyzed by Erowid's DrugsData service were actually other 2C- compounds.] 8/12/18 6:30: 3mg 2c-ef dosed orally 6:45: actually feeling slightly drowsy.

Pronounced Visuals, Time Distortion positive exp #118300

I reviewed several reports on lower doses of this substance, which coincided with its recent appearance in the research chemical market. Users experimented with smaller amounts but generally agreed that 20 mg would be suitable. Shulgin also speculated on a dosage range of 20-40 mg for 2C-EF.

The Frequency Inside Me cautionary exp #119372

T+0:00 - Dose 20 mg 2C-EF, same batch as before. I expected something intense but manageable like last time, even though this is far beyond the typical dosing range for this psychedelic, in the back of my head I had my concerns about the safety, but since I've done this before I felt some confidence.

Bluelight 6 threads 6 neutral visit

2c Ef First Time Smooth As Silk And Warm Like Sunshine neutral

2C-EF - First Time - 7-4-2019 - "Smooth As Silk and Warm Like Sunshine" By Xorkoth **NOTE: I later discovered via GC/MS confirmation that this was actually a blend of 2C-C, 2C-T-2, and 2C-T-7, being sold as 2C-EF by an unscrupulous longtime vendor.

2c Ef 7mg Seasoned Tripper Clear Serenity neutral

My first trial with 2C-EF, as best as I can trust. Has not been sent off for testing yet but vendor has a long standing reputation spanning near a decade. Some intro stuff, if you'd like to skip, find the cat...

2c Ef 10 Mg New Experience Its A Wonderful Night neutral

A footnote in Pihkal reckons that 2C ?€“ EF would be a winner if anyone ever made it & the dosage would likely be between 12 and 24 mgs. I was told the dosage ought to be between 6 and 12 mgs which is probably about right T +O.OO 10mgs dosed in juice for me and my friend whom we?€™ll call Kevin.

2c Ef 14mg Experienced The Balance Of Profundity And Sensuality neutral

2C-EF ~14 mg 12:30 Took with juice. 12:45 Some of the normal stirrings that something is going to happen. 1:00 Starting to feel some intense pleasure/body high. Head is feeling fuzzy. Very aphrodiasiac-like. 1:15 Some breathing of curtains happening. Still very pleasurable and smooth come up. No anxiety at all.

2c Ef First Time Another Wonderful Drug Experience neutral

Well the Autumn equinox came and I had a yearning to try a new psychedelic. Originally it was to be 4-allyloxy-3,5-dimethoxthyphenethylamine, bute fate conspired to make it not so. In the end I went with 2C-EF and lordy was it a good decision (nobody mention the sychrononicity word!~).

2c Ef 28 Mgs 2c Ef You Up neutral

I tried 28 mgs of 2c-ef recently, which had been lab tested and verified, and...wow! What a powerful substance! I decided on 28 mgs based off of reports and comparsons to 2c-e.

2C-EF's nerd page Pharmacology, chemical data, effect profiles, and more

→

Helpful Links

📘 Experience Reports 📖 dose.wiki 📖 PsychonautWiki

Report an issue or suggest an edit

Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 2C-EF? Let us know. Reports are reviewed by moderators — this is not posted publicly.

2C-EF Encyclopedic Encyclopedic Typical encyclopedia coverage. Cross-reference for important decisions. 2 corroborating sources 1 ROA with full dose ladder duration data present 18 combo interactions documented classified Research-chemical dose data not in PW/TripSit (unverifiable)