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    2C-IP molecular structure

    2C-IP Stats & Data

    NPS DataHub
    MW223.32
    FormulaC13H21NO2
    CAS1498978-47-4
    IUPAC2-(2,5-dimethoxy-4-propan-2-ylphenyl)ethanamine
    SMILESNCCc1cc(OC)c(C(C)C)cc1OC
    InChIKeyXUGPCRRUMVWELT-UHFFFAOYSA-N
    Phenethylamines; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Phenethylamine
    Psychoactive Class Psychedelic
    Half-Life Unknown; prolonged clinical effect suggests ≥6 h terminal half‑life

    Receptor Profile

    Receptor Actions

    Agonists
    5-HT2A receptor agonist

    History & Culture

    2C-iP, also known by the alternative name "Jelena," is a psychedelic phenethylamine first synthesized by Dmitri Ger. The compound is a structural analogue of 2C-P and has been distributed through online markets as a designer drug. Limited documentation exists regarding the precise timeline of its synthesis or initial appearance in research chemical markets.

    Effect Profile

    Curated + 1 Reports
    Psychedelic 5.8

    Strong visuals with mild auditory effects and body load, low headspace

    Visual Intensity×3
    10
    Headspace Depth×3
    2
    Auditory Effects×1
    4
    Body Load / Somatic Effects×1
    4

    Tolerance & Pharmacokinetics

    drugs.wiki
    Half-Life
    Unknown; prolonged clinical effect suggests ≥6 h terminal half‑life
    Addiction Potential
    Low; physical dependence unlikely. Psychological craving is uncommon and tempered by long duration and slow onset, consistent with 2C‑x reports.

    Tolerance Decay

    Full tolerance 2d Half tolerance 5d Baseline ~14d

    Acute tolerance appears to build rapidly after one session and decays over roughly 1–2 weeks, consistent with broad psychedelic patterns; exact kinetics for 2C‑iP are unknown. Cross‑tolerance with other serotonergic psychedelics is expected.

    Cross-Tolerances

    Other 2C‑x phenethylamines
    60% ●○○
    Classical tryptamines (LSD/psilocin)
    40% ●○○

    Experience Report Analysis

    Erowid
    1 Reports
    2017–2017 Date Range
    1 With Age Data

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Legal Status

    Country Status Notes
    Canada Schedule III (CDSA) Classified as a controlled substance under Schedule III of the Controlled Drugs and Substances Act as of October 31, 2016. Schedule III substances are subject to criminal penalties for possession, trafficking, and production without authorization, though penalties are generally less severe than those for Schedule I and II substances.

    Harm Reduction

    drugs.wiki

    Human data for 2C‑iP are extremely limited; most guidance comes from a handful of forum reports and a single curated trip report, so conservative dosing and careful titration are essential. Onsets around 2–3 hours have been reported for oral use, which increases the risk of accidental overdosing via early redosing—wait several hours before considering any additional dose. Long total durations of 12–16+ hours have been described at common to strong doses; plan set, setting, and sleep accordingly. Phenethylamine psychedelics in the 2C‑x family commonly produce mental and physical stimulation; monitor heart rate, blood pressure, temperature, and hydration, especially if physically exerting or in hot environments. Insufflation of 2C‑x compounds is widely reported to be painful and irritating to the nasal mucosa and may increase nausea on come‑up; oral routes are generally more tolerable for many. An effect‑indexed 50 mg oral report flagged possible urinary/bladder discomfort during/after the experience—frequency and mechanism are unknown; if burning, difficulty urinating, or flank pain occur, hydrate, avoid further dosing, and seek medical care if severe. Because 2C‑iP is rare in the market, mislabeling or substitution is plausible; use reagent tests and, where available, lab drug checking—do not assume a 2C‑B pill/powder contains 2C‑B or any 2C at all. If a difficult experience develops, reduce sensory load, hydrate, and consider a low, measured benzodiazepine dose only if necessary; avoid alcohol and additional stimulants. Cross‑tolerance with other serotonergic psychedelics is expected; spacing trips by at least 1–2 weeks helps reduce tolerance and psychological strain. Data here are anecdotal; individuals vary widely in sensitivity and response, so risk management should err on the side of under‑dosing and patience.

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