2C-T-2 - Substance Search

Summary TheDrug.Wiki TripSit PsychonautWiki

2C-T-2 is a potent 5-HT2A/2B/2C partial agonist with a steep dose-response curve and pronounced gastrointestinal distress. PIHKAL identifies 12-25 mg as the active range; harm reduction consensus converges on 15-22 mg oral for full effects. Sulfur-containing 2C-T compounds produce intense, sometimes uncomfortable body load with vasospasm risk, particularly via insufflation.

Perspectives

“I don’t feel this for fully an hour, but when I do it is quite a weight. It feels good to work it through. It is OK to be with pain. You can’t eliminate it. And it is OK to contact your deep pools of anger. And all of it stems from the lack of acknowledgment. All the macho carrying on, the fights, the wars, are ways of demanding attention, and getting even for not having had it in one’s life. I am experiencing more deeply than ever before the importance of acknowledging and deeply honoring each human being. And I was able to go through and resolve some judgments with particular persons.”

— Alexander Shulgin, PiHKAL (with 12 mg)

Dose Information TheDrug.Wiki TripSit PsychonautWiki

ROA	Light	Common	Strong	Heavy
Oral	5-10mg	10-20mg	20-30mg	30mg+
Insufflated	5-10mg	10-20mg	20-25mg	25mg+

Light Common Strong Heavy

Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

ROA	Onset	Comeup	Peak	Offset	After Effects	Total
Oral	30-60 min	30-90 min	2.5-5 hrs	2-4 hrs	2-6 hrs	5-10 hrs
Insufflated	4-15 min	15-30 min	2-4 hrs	1-2 hrs	2-4 hrs	3-7 hrs
Rectal	15-30 min	30-60 min	2-4 hrs	2-3 hrs	2-4 hrs	5-8 hrs

Effect Profile

188 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Validated against 148 Erowid trip reports
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Psychedelic 8.8

Intense+ 9/10

Strong visuals, headspace, auditory effects, and body load

Visual Intensity ×3

10

visual geometry external hallucinations internal hallucinations color enhancement autonomous entities drifting +8 more

Headspace Depth ×3

10

conceptual thinking thought connectivity introspection feelings of interdependent opposites emotion enhancement perspective alterations +5 more

Auditory Effects ×1

10

auditory distortion auditory enhancement auditory hallucinations auditory hallucination

⚠ Body Load / Somatic Effects ×1

10

temperature regulation suppression vasoconstriction nausea muscle tension stomach cramps increased heart rate

Empathogen 8.1

Intense 8/10

Strong stimulation, sensory enhancement, and euphoria with moderate empathy

Empathy / Social Openness ×3

7

empathy

Euphoria / Mood Elevation ×2

8

euphoria emotion enhancement

Stimulation ×1

10

stimulation wakefulness restlessness increased heart rate

Sensory Enhancement ×1

10

enhanced tactile sensation tactile enhancement spontaneous tactile sensations color enhancement acuity enhancement visual acuity enhancement

Based on reports from:

PiHKAL PiHKAL #40: 2C-T-2 Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki 2C-T-2

Tolerance

Build-up develops rapidly after a single use

Reset 7–14 days for baseline

Tolerance Decay

Full tolerance 8h Half tolerance 3d Baseline ~7d

Rapid acute tachyphylaxis within the same session; cross-tolerance expected across serotonergic psychedelics. Data are mostly anecdotal across 2C‑x; spacing 7–14 days is commonly advised to reset.

Cross-Tolerances

classical psychedelics (LSD, psilocybin)

60%

other 2C phenethylamines

50%

Effects Erowid Bluelight

Aggregated from 148 Erowid and 40 Bluelight experience reports

Positive Effects 72

Color Enhancement 52.1% 89%

Music Enhancement 44.1% 86%

Stimulation 38.3% 81%

Euphoria 31.4% 85%

Empathy 29.8% 86%

Focus Enhancement 28.8% 77%

Tactile Enhancement 28.2% 83%

Introspection 23.9% 81%

Surface Breathing 22.5% 86%

Body High 22.3% 87%

Melting/flowing 20.0% 84%

Closed-Eye Visuals 19.7% 90%

Contentment 17.5% 81%

Visual Trails 17.5% 81%

Entity Imagery 17.5% 83%

Geometric Imagery 15.0% 84%

Emotional Openness 15.0% 80%

Sociability Enhancement 15.0% 80%

Patterning 15.0% 86%

Open-Eye Visuals 13.8% 84%

Adverse Effects 47

Nausea 50.0% 85%

Body Load 47.5% 84%

Anxiety 38.8% 87%

Vomiting 35.0% 91%

Auditory Effects 24.5% 84%

Confusion 24.0% 82%

Muscle Tension 21.8% 88%

Fear 17.5% 86%

Headache 16.5% 84%

Panic 15.0% 87%

Sadness 12.5% 77%

Memory Suppression 11.7% 80%

Jaw Clenching 10.1% 85%

Insomnia 10.0% 76%

Increased Heart Rate 8.1% 70%

Motor Impairment 7.5% 75%

Emotional Blunting 7.5% 77%

Dysphoria 7.5% 80%

Temporal Disorientation 7.5% 80%

Body Distortion 7.5% 83%

Combinations TripSit

PiHKAL / TiHKAL Shulgin

PiHKAL #40: 2C-T-2

“I don’t feel this for fully an hour, but when I do it is quite a weight. It feels good to work it through. It is OK to be with pain. You can’t eliminate it. And it is OK to contact your deep pools of anger. And all of it stems from the lack of acknowledgment. All the macho carrying on, the fights, the wars, are ways of demanding attention, and getting even for not having had it in one’s life. I am experiencing more deeply than ever before the importance of acknowledging and deeply honoring each human being. And I was able to go through and resolve some judgments with particular persons.”

— Alexander Shulgin, PiHKAL (with 12 mg)

2C-T-2's nerd page Pharmacology, chemical data, effect profiles, and more

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Helpful Links

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