This compound had long been on my bucket list, and Iยm grateful I received a sample as a gift. -->I have tried it once before today at 3mg, which was a low but pleasant dose comparable to ~15mg 2C-B HCl. It was enough to let it reveal its character a bit and I remember being impressed by the effects.
2C-TFM
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- partial dose data
- duration data present
- 27 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- partial dose data
- duration data present
- 27 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: 2c-cf3
Summary
2C-TFM is the most potent simple 2C analogue, with human active doses of 3-6 mg according to Trachsel and Shulgin. It rivals DOI and DOB in receptor binding affinity (Ki โ 75 nM at 5-HT2A/C). Because it is usually synthesized from 2C-I, retail batches from the mid-2000s were often contaminated with ~50% unreacted 2C-I, leading to mixed effects and legal complications in jurisdictions where 2C-I is prohibited.
Dose Information
| ROA | Light |
|---|---|
| Oral / Sublingual | 1mg-2mg |
| Insufflated (Intranasal) | 0.5mg-1.5mg |
Light
Sources
Oral / Sublingual
Dose ladder — DrugsPROInsufflated (Intranasal)
Dose ladder — DrugsPROOnset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral / Sublingual | 15-30 min | 30-60 min | 1-3 hrs | 2-3 hrs | 3.75-7.5 hrs |
| Insufflated (Intranasal) | 5-15 min | 15-30 min | 1-3 hrs | 2-3 hrs | 3.33-6.75 hrs |
Effect Profile
14 reportsScores (0–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
6.6
Strong+
7/10
Strong visuals with moderate auditory effects and body load, mild headspace
Visual Intensity
×3
10
color enhancement
synaesthesia
drifting
tracers
pattern recognition enhancement
color shifting
+1 more
Headspace Depth
×3
4
introspection
time distortion
confusion
Auditory Effects
×1
7
music enhancement
synaesthesia
Body Load / Somatic Effects
×1
6
nausea
muscle tension
increased heart rate
Based on reports from:
Tolerance
Build-up
develops rapidly after a single use
Reset
7โ14 days for baseline
Tolerance Decay
Full tolerance
1h
Half tolerance
10d
Baseline
~14d
Effects
Aggregated from 4 single-substance Erowid and 10 Bluelight experience reports; 2 Erowid reports where another drug was taken too are left out
Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.
Too few reports for bars: these effects come from 4 single-substance Erowid and 10 Bluelight reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?
Effect glossary — · full glossary
Positive Effects 46
7 of 10
80%
9 of 14
78%
6 of 10
88%
7 of 14
81%
7 of 14
90%
4 of 10
81%
4 of 10
85%
5 of 14
85%
3 of 10
83%
3 of 10
93%
3 of 10
73%
3 of 10
83%
2 of 10
85%
2 of 10
75%
2 of 10
82%
2 of 10
85%
2 of 10
82%
2 of 10
78%
2 of 10
78%
2 of 10
82%
Show 26 more positive effects
2 of 10
78%
2 of 10
78%
2 of 10
72%
1 of 10
90%
1 of 10
85%
1 of 10
80%
1 of 10
85%
1 of 10
90%
1 of 10
80%
1 of 10
75%
1 of 10
85%
1 of 10
75%
1 of 10
80%
1 of 10
75%
1 of 10
85%
1 of 10
90%
1 of 10
80%
1 of 10
80%
1 of 10
75%
1 of 10
80%
1 of 10
75%
1 of 10
80%
1 of 10
80%
1 of 10
75%
1 of 10
80%
1 of 10
70%
Adverse Effects 8
3 of 10
72%
2 of 10
72%
2 of 10
70%
2 of 10
80%
1 of 10
85%
1 of 10
75%
1 of 10
70%
1 of 10
65%
Combinations
Cross-Check 2C-TFM with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 6 reports 6 positive visit
Fortuitously and fortunately having been able to experience this currently still rare and almost unknown substance 2C-TFM hydrochloride, which was of high purity assessed by NMR, I wish to share a few observations and an excerpt of a report noted during a second experience with this substance.
First, Mild and Pleasant Encounter With 2C-TFM Fortuitously and fortunately having been able to experience this currently still rare and almost unknown substance 2C-TFM hydrochloride, which was of high purity assessed by NMR, I share a brief summary of the effects encountered during the first experience with 2C-TFM.
A Few Notes on the Effects of 2C-TFM I was fortunate to be gifted this rare material by a dear friend and chemist. H-NMR analysis of the material indicated that it was of high purity. Setting: Indoors, during a summer evening. No other drugs or medications were consumed within 1 week before this session.
Prompted by two previous, precious, gratuitous and gratefully appreciated experiences occasioned via, through and with 2C-TFM characterizing the effects and qualitative nature of action at lower to moderate doses, there follows a description of a third adventure evoked by 6.5 mg of this pristine powder and an evaluatio...
Set ย Not perfect but Iยve had worse. An hours sleep the night before makes me feel sleepy Setting ย My House, kids due in from school ย busy household ย Iยm used to it T+0.00 ย Drink 3mgs of dissolved drug T+ 0.10 Faint perceptual changes, continue reading my book.
Bluelight 6 threads 5 positive 1 neutral visit
2C-TFM 8mg - Fun with FANz PHENz and 2C-TFMz 2C-TFM 8mg FUN WITH FANz, PHENz and 2C-TFMz There's not much info on the web about this "newbie" phenethylamine so I thought it would be nice to write up a trip report.
I thought it was about time to post an experience with this fairly unknown new research chemical. I've tried it a few other times (with oral doses of 4 and 5mg respectively), which produced a mild ++ buzz peppered with obscene amount of laughter and slight visuals. It was shallow, but quite a bit of fun.
2C-TFM - second time - 4mg 5:50 - I eat a capsule of 4mg -tfm, i'm excited. 6:00 - Seems like I already feel something! I'm gonna hop in the shower real quick.. Its about 9pm now, friends came over, so i got off the computer. I just boosted with about 3mg held under the tongue for a while before swallowing.
I just took about 6mg of 2C-TFM at around 8PM (Central Time), and I could tell from the get go that I'd want to write a trip report. I will keep adding as the night progresses... +00:45 Went to Wal-Mart to get a TV-out cable for my friend M's computer so we could watch Futurama on my TV.
2C-TFM Set โ Not perfect but Iโve had worse. An hours sleep the night before makes me feel sleepy Setting โ My House, kids due in from school โ busy household โ Iโm used to it T+0.00 โ Drink 3mgs of dissolved drug T+ 0.10 Faint perceptual changes, continue reading my book.
I've experimented with 2c-tfm enough times (four total) to get a feel for what is a fairly unknown psychedelic, and finally found a dose which seems to show all of the charcteristics of the drug (17mg of the contaminated sample which contains 2c-i, and other PEA's) If i was to compare this to any other psychedelic drug...
2C-TFM's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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Name
2C-TFM
Unit
mg
Description
2C-TFM Source: SubstanceSearch (substancesearch.com) Oral / Sublingual dose (mg): threshold 1 ยท light 1-2 Insufflated (Intranasal) dose (mg): threshold 0.5 ยท light 0.5-1.5 Oral / Sublingual duration: onset 15-30m ยท come-up 0.5-1h ยท peak 1-3h ยท offset 2-3h ยท total 3.75-7.5h ยท after-effects 2-6h Insufflated (Intranasal) duration: onset 5-15m ยท come-up 15-30m ยท peak 1-3h ยท offset 2-3h ยท total 3.33-6.75h ยท after-effects 2-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
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