Psychoactive Class
Dissociative
Receptor Profile
Receptor Actions
Antagonists
NMDA receptor antagonist (noncompetitive)
Inhibitors
Dopamine reuptake inhibitor
Receptor Binding
NMDA
antagonist
History & Culture
3-Cl-PCP is a novel dissociative from the arylcyclohexylamine class that emerged as part of a wave of designer drugs in the early 2020s. It was first identified in Slovenia in December 2020, marking its initial appearance on the recreational drug market. The substance belongs to a group of novel dissociatives that were developed and marketed around the same time, reportedly designed to produce effects similar to those of MXE (methoxetamine). This cohort of related compounds includes 3-F-PCP, 3-Me-PCP, DMXE, MXPr, MXiPr, and HXE, all of which appeared on the research chemical market during this period.
Effect Profile
Curated + 1 Reports
Dissociative
6.6
Strong dissociative depth, motor impairment, and mania with moderate insight
Dissociative Depth×3
10
Mania / Compulsion×1
8
Insight / Novel Thought×2
7
Motor / Sensory Impairment×1
10
Based on reports from:
Duration Timeline
Bluelight
Onset
Comeup
Peak
Offset
After Effects
Oral
Insufflated
Intramuscular
Smoked
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Full tolerance
1d
Half tolerance
21d
Baseline
~28d
Experience Report Analysis
Erowid
1
Reports
2020–2020
Date Range
1
With Age Data
Demographics
Gender Distribution
Age Distribution
Reports Over Time
Legal Status
| Country | Status | Notes |
|---|---|---|
| Germany | Controlled (NpSG) | Controlled substance under the Neue-psychoaktive-Stoffe-Gesetz (New Psychoactive Substances Act), which prohibits the production, distribution, and import of new psychoactive substances. |
| Hungary | Illegal | Became a controlled substance in April 2021. Production, distribution, and possession are prohibited under national drug legislation. |
| Switzerland | Uncontrolled | Not listed as a controlled substance as of 2021. However, legal status may have changed since this assessment. |
| United Kingdom | Illegal | Prohibited under the Psychoactive Substances Act 2016. It is illegal to possess, produce, supply, or import this substance. |