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    Disclaimer
    โš  PCP and its analogues are potent dissociatives with significant risk of psychosis, violent behavior, and overdose. Effects are highly unpredictable and dose-sensitive.
    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    3-EtO-PCP Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 18 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Summary dose.wiki

    3-EtO-PCP is a novel arylcyclohexylamine with an ethoxy substituent at the 3-position of the phenyl ring, making it a heavier and more lipophilic analogue of 3-MeO-PCP. User reports suggest strong dissociation with a sedating, muddy headspace more similar to DCK than the manic clarity of 3-MeO-PCP. Insufflation causes severe nasal pain and prolonged throat irritation; oral or sublingual administration is recommended.

    Dose Information dose.wiki Drugs.Wiki

    No curated dose ladder is available for this substance. The figures below are drawn from SubstanceIndex (DoseWiki) as a fallback — often a conservative threshold only. Treat them as approximate and cross-reference before use.

    Dose basis. Community-derived; start low and titrate. Avoid redosing for at least 2 hours due to delayed cresting of effects. Use a calibrated milligram scale or volumetric dosing to prevent large missteps. Multiple user reports describe intense delayed nasal/throat burn and lingering soreness; oral administration is generally safer on mucosa. Consider avoiding this ROA. (Dose figures and this note are from Drugs.Wiki.)

    ROA Light Common Strong Heavy
    Oral 30-50mg 50-80mg 80-120mg 120mg+
    Insufflated 10-25mg 25-50mg 50-80mg 80mg+
    Vaporized / Smoked 5-15mg 15-30mg 30-50mg 50mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki Drugs.Wiki

    ROA Onset Peak Offset After Effects Total
    Oral 30-45 min 1-3 hrs 2-4 hrs 4-8 hrs 3.5-7.75 hrs
    Insufflated 10-20 min 1-3 hrs 2-4 hrs 4-8 hrs 3.17-7.33 hrs
    Vaporized / Smoked 1-5 min 1-2 hrs 2-3 hrs 4-8 hrs 3.02-5.08 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 6.0
    Strong 6/10

    Strong dissociative depth and motor impairment with mild mania, low insight

    Dissociative Depth ×3
    10
    depersonalization derealization physical disconnection visual disconnection spatial disorientation memory suppression +1 more
    Mania / Compulsion ×1
    4
    disinhibition stimulation
    Insight / Novel Thought ×2
    3
    conceptual thinking
    Motor / Sensory Impairment ×1
    10
    motor control loss physical disconnection tactile suppression numbness spatial disorientation visual disconnection +1 more

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 3-EtO-PCP there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "3-EtO-PCP (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    3-EtO-PCP
    Unit
    mg
    Description
    3-EtO-PCP
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (mg): threshold 20-30 ยท light 30-50 ยท common 50-80 ยท strong 80-120 ยท heavy 120+
    Insufflated dose (mg): threshold 10 ยท light 10-25 ยท common 25-50 ยท strong 50-80 ยท heavy 80+
    Vaporized / Smoked dose (mg): threshold 5 ยท light 5-15 ยท common 15-30 ยท strong 30-50 ยท heavy 50+
    
    Oral duration: onset 30-45m ยท peak 1-3h ยท offset 2-4h ยท total 3.5-7.75h ยท after-effects 4-8h
    Insufflated duration: onset 10-20m ยท peak 1-3h ยท offset 2-4h ยท total 3.17-7.33h ยท after-effects 4-8h
    Vaporized / Smoked duration: onset 1-5m ยท peak 1-2h ยท offset 2-3h ยท total 3.02-5.08h ยท after-effects 4-8h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 65 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2โ€“4 weeks for noticeable reduction

    Tolerance Decay

    Half tolerance 14d Baseline ~28d

    Community consensus: rapid functional tolerance after one heavy session; partial fade in several days; baseline often in 10โ€“14 days. Crossโ€‘tolerance likely with other arylcyclohexylamines (e.g., PCP, ketamine, 3โ€‘MeOโ€‘PCP) and possibly DXM.

    Effects dose.wiki

    Positive
    • Pain relief
    • Residual stimulation
    • Physical euphoria
    • Stimulation
    Negative
    • Nystagmus
    • Numbness
    • Loss of balance
    • Nausea
    Neutral
    • Sedation
    • Physical disconnection
    Positive
    • Cognitive euphoria
    • Conceptual thinking
    Negative
    • Depersonalization
    • Derealization
    • Motor control loss
    • Thought deceleration
    • Memory suppression
    • Amnesia
    Neutral
    • Dissociative anesthesia
    • Time distortion
    Positive
    • Increased music appreciation
    • Tactile enhancement
    Negative
    • Spatial disorientation
    • Tactile suppression
    • Derealization
    • Disinhibition
    • Double vision
    • Pattern recognition suppression
    Neutral
    • Visual disconnection
    • Auditory distortion

    Combinations

    Cross-Check 3-EtO-PCP with another substance

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