3-Hydroxyphenazepam
Aliases: Hpnz, 3-hop, 3-oh-p, 3ohphenazepam, 3-ho-phenazepam, 3hophenazepam, 3-ho-p, 3hop, 3ohp, 3-oh-phenazepam
Categories
Summary
3-Hydroxyphenazepam is a potent designer benzodiazepine and active metabolite of phenazepam and cinazepam. It is 5-10 times more potent than diazepam and has diminished muscle relaxant properties compared to phenazepam while retaining strong sedative and anxiolytic effects. Recreational doses carry high risk of blackouts, amnesia, and respiratory depression, especially when combined with other CNS depressants. Due to its long half-life and potency, volumetric dosing is strongly recommended. Tolerance and dependence develop rapidly with repeated use, and abrupt cessation can cause life-threatening withdrawal seizures.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 0.5-1mg | 1-2mg | - | 2-4mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 10-60 min | 30-90 min | 2-6 hrs | 4-8 hrs | 1-36 hrs | 600-0 min |
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Effects
Positive
- Muscle relaxation
- Anxiolytic
- Muscle Relaxant
- Physical euphoria
Negative
- Motor impairment
- Respiratory depression
- Sedation
- Sedative
- Dystaxia
- Hypnotic
Positive
- Anxiety suppression
- Cognitive euphoria
Negative
- Amnesia
- Motor control loss
- Emotion suppression
- Thought deceleration
- Analysis suppression
- Compulsive redosing
- Dizziness
- Delusions of sobriety
Positive
- Increased music appreciation
- Increased libido
- Appetite enhancement
Negative
- Disinhibition
- Visual acuity suppression
- Acuity suppression
- Dehydration
- Light sensitivity
- Dulled perception
- Perception of bodily heaviness