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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    3-MAR Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 18 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Stimulant Research-chemical

    Summary dose.wiki

    3-MAR produces a clear, focused stimulation reminiscent of 4-MAR but with more pronounced head pressure and emotional lability. Users describe strong synergy with amphetamine yet diminishing returns when redosed in isolation. Nasal administration is sharply caustic; vaporizing the freebase yields a rapid rush but encourages compulsive re-administration.

    Dose Information dose.wiki Drugs.Wiki

    Dose basis. Ranges are compiled from scattered user reports and analog extrapolation (not clinical data). Potency may vary by isomer ratio (cis/trans) and salt vs freebase. Start low, titrate cautiously, and avoid rapid redosing. User reports describe notable causticity and mucosal irritation with aminorex analogues; dilute finely, avoid repeated back‑to‑back lines, and rinse gently with isotonic saline post‑use. (Dose figures and this note are from Drugs.Wiki.)

    ROA Light Common Strong Heavy
    Oral 5-10mg 10-20mg 20-35mg 35mg+
    Insufflated 3-7mg 7-15mg 15-25mg 25mg+
    Smoked 2-5mg 5-10mg 10-20mg 20mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki Drugs.Wiki

    ROA Onset Peak Offset After Effects Total
    Oral 20-40 min 0.5-3 hrs 2-6 hrs 4-24 hrs 2.83-9.67 hrs
    Insufflated 5-10 min 0.5-3 hrs 2-6 hrs 4-24 hrs 2.58-9.17 hrs
    Smoked <1-2 min 0.5-3 hrs 2-6 hrs 4-24 hrs 4-12 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 5.1
    Moderate+ 5/10

    Strong anxiety/jitters with moderate stimulation, mild euphoria and focus

    Stimulation / Energy ×3
    7
    stimulation increased energy wakefulness
    Euphoria / Mood Lift ×2
    5
    euphoria motivation enhancement
    Focus / Productivity ×2
    5
    focus enhancement motivation enhancement
    ⚠ Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate bruxism vasoconstriction
    View methodology →

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 3-MAR there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "3-MAR (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    3-MAR
    Unit
    mg
    Description 
    3-MAR
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): threshold 5 · light 5-10 · common 10-20 · strong 20-35 · heavy 35+
Insufflated dose (mg): threshold 3 · light 3-7 · common 7-15 · strong 15-25 · heavy 25+
Smoked dose (mg): threshold 1-2 · light 2-5 · common 5-10 · strong 10-20 · heavy 20+

Oral duration: onset 20-40m · peak 0.5-3h · offset 2-6h · total 2.83-9.67h · after-effects 4-24h
Insufflated duration: onset 5-10m · peak 0.5-3h · offset 2-6h · total 2.58-9.17h · after-effects 4-24h
Smoked duration: onset <1-2m · peak 0.5-3h · offset 2-6h · total 4-12h · after-effects 4-24h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 15 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 3d Baseline ~21d

    Anecdotal: tolerance rises rapidly during a binge and partially recovers after 3–5 days; baseline by 7–14 days if no further use. Cross‑tolerance with other aminorex derivatives and common stimulants is likely but unquantified.

    Cross-Tolerances

    4‑Methylaminorex (4‑MAR)
    70%
    Amphetamine‑like stimulants
    40%

    Effects dose.wiki

    Positive
    • Stimulation
    • Increased energy
    Negative
    • Teeth grinding
    • Vasoconstriction
    • Increased heart rate
    • Insomnia
    • Pupil dilation
    • Increased blood pressure
    • Increased perspiration
    • Bruxism
    Positive
    • Euphoria
    • Focus enhancement
    • Motivation enhancement
    • Sociability enhancement
    • Emotion enhancement
    • Thought connectivity
    • Wakefulness
    Negative
    • Anxiety
    • Compulsive redosing
    Neutral
    • Talkativeness
    Positive
    • Visual enhancement
    • Increased libido
    • Increased music appreciation
    • Tactile enhancement
    Negative
    • Light sensitivity
    • Appetite suppression
    • Dehydration
    • Disinhibition
    • Double vision
    Neutral
    • Dulled perception

    Combinations

    Cross-Check 3-MAR with another substance

    3-MAR's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 dose.wiki 📖 PsychonautWiki